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Thoracic Surgery clinical trials

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NCT ID: NCT06310785 Not yet recruiting - General Anesthesia Clinical Trials

Esketamine Anesthesia in Thoracic Surgery

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Esketamine group was induced with esketamine 0.5 mg/kg, propofol 2 mg/kg, and rocuronium bromide 0.9 mg/kg. Anesthesia is maintained with propofol 5 mg/kg/h and esketamine 0.5 mg/kg/h. Anesthesia induction in the opioid group Sufentanil 0.5 ug/kg, propofol 2 mg/kg, rocuronium bromide 0.9 mg/kg. Anesthesia is maintained with propofol 5 mg/kg/h and remifentanil 1 ug/kg/h.

NCT ID: NCT05901389 Not yet recruiting - Pain, Postoperative Clinical Trials

Continuous Lidocaine Infusion Via Closed Chest Drainage Tube for Pain Control After Thoracoscopic Partial Lung Resection

Start date: June 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the effects on postoperative analgesia of continuous lidocaine infusion via closed chest drainage tube for patients undergoing thoracoscopic partial lung resection. The main questions it aims to answer are: - To explore whether continuous lidocaine pumping via closed chest drainage tube has good analgesic and anti-inflammatory effects for patients undergoing partial thoracoscopic pneumonectomy. - Whether the multimodal analgesia combined with continuous lidocaine pump can reduce the postoperative application of opioids, reduce the occurrence of postoperative complications, and promote the recovery of postoperative lung function and accelerate recovery. For participants who undergoing the thoracoscopic partial lung resection with postoperative indwelling drainage tube, the epidural tube fixed in the drainage tube is connected to the completed infusion pump (marking the chest drain for analgesia). The comparison group only accept the intravenous analgesia after surgery.

NCT ID: NCT05525923 Not yet recruiting - Thoracic Surgery Clinical Trials

OpalGenix (TS) - Personalized Postoperative Pain Management Following Thoracic Surgery in Adults

Start date: October 1, 2023
Phase:
Study type: Observational

The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone, in adults following thoracic surgery. Major inpatient thoracic surgeries (TS) for lung disease are common and extremely painful surgeries and are associated with sever post-surgical pain, high incidence of chronic post-surgical pain (CPSP), excess opioid use, costly immediate postoperative opioid adverse events (AEs), and long hospital stays. This study is aiming to develop proactive risk prediction algorithms for precision surgical pain relief in adult TS patients through comparison of actual clinical outcomes with standard of care to predicted outcomes based on personalized risk assessments.

NCT ID: NCT05482230 Not yet recruiting - Anesthesia Clinical Trials

Application of Tracheal Intubation in Lateral Position in Thoracic Surgery

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

This study is a pilot study of DLT or BB intubation using a visual laryngoscope in lateral position,To investigate the feasibility of DLT and BB intubation in lateral position,To compare the influence of four endotracheal intubation methods on intrapulmonary shunt,It provides safety guarantee for chest operation under spontaneous breathing anesthesia.

NCT ID: NCT05204043 Not yet recruiting - Pain Clinical Trials

Peter Hess® Sound Massage for Reducing Anxiety and Pain in Cardiac Surgery

MuSoCa
Start date: January 2022
Phase: N/A
Study type: Interventional

Cardiac surgery patients often undergo anxiousness and pain. Before surgery, anxiety is often caused by the idea of sternotomy, extracorporeal circulation, fear of post-operative pain, and even death. After surgery anxiety and pain can be the consequences of operative and peri-operative procedures. The investigators believe that reducing stress and pain by a relaxation therapy would lead to better stay in hospital and a better recovery after surgery. Music Care® relaxation technique consists into listening to an audio relaxing soundtrack chosen by the patient. This technique has already proven with several clinical studies its efficiency for reducing pain and anxiety in hospital. The research consists of comparing this technique to Peter Hess® sound massage for reducing pain and anxiety. The Peter Hess® sound massage is a holistic relaxation technique that uses sound vibrations generated by therapeutic singing bowls. Patients will be randomized in one of the two groups (Music Care® or Peter Hess®).

NCT ID: NCT04190966 Not yet recruiting - Smoking Cessation Clinical Trials

Smoking Cessation in the Surgical Pathway Before Major Lung Surgery

MURRAY
Start date: January 31, 2020
Phase: N/A
Study type: Interventional

This is a feasibility study of a personalised, integrated smoking cessation in the surgical pathway in patients undergoing major elective thoracic surgery when compared to usual care of standard community/hospital based NHS smoking cessation. Half the patients will receive the intervention and half the patients will receive usual care.

NCT ID: NCT04167046 Not yet recruiting - Thoracic Surgery Clinical Trials

Erector Spinae Block in First Rib Resection: a Monocentric Before-after Study

MERCOTE
Start date: November 2019
Phase:
Study type: Observational

First rib resection surgery for thoracic outlet syndrome is associated with an intense postoperative pain. It leads to significant consumption of nonsteroidal anti-inflammatory drugs and opioids, and hospitalization for several days. In our center, first rib resection surgery was usually performed under general anesthesia combined with diffuse local infiltration of the axillary fossa. Erector spinae block is an interfascial block where a local anesthetic is injected between the erector spinae muscle and the transverse process, in order to obtain a multimetameric analgesia. It has now shown its efficacy and its safety in thoracic and abdominal surgeries by decreasing the morphine consumption and pain scores. Since November 2018, this erector spinae block is systematically performed preoperatively for first rib resection in our center, in association with a general anesthesia. Patient satisfaction seems important but remains to be assessed objectively. In a before-after study, our goal is to assess the impact of the use of erector spinae block on postoperative pain in the first rib resection surgery.

NCT ID: NCT04159077 Not yet recruiting - Thoracic Surgery Clinical Trials

REduction of Post-Operative Urinary Retention With Tamsulosin Versus Placebo (REPOURT- P) Trial

REPOURT-P
Start date: July 30, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study are to determine the efficacy of tamsulosin compared to placebo in reducing post-operative urinary retention and improving other clinical outcomes in people undergoing thoracic surgery.

NCT ID: NCT03734276 Not yet recruiting - Physical Activity Clinical Trials

Effect of High-intensity Training on the Level of Physical Activity After Thoracoscopy Surgery: a Pilot Study

HITAT
Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Goal of this study is to evaluate management with high intensity re-entrainment during the postoperative hospital phase. This type of early treatment with as little intervention time has so far never been done. The investigators therefore want to carry out this feasibility study in order to collect the data needed to calculate the number of randomized control trial. Investigators will also evaluate the feasibility of this project concerning recruitment, intervention in the hospital phase and data collection once the return home. The evaluation of the activity will be done one month after the return to home by means of a actigraphy of one week.

NCT ID: NCT03628040 Not yet recruiting - Analgesia Clinical Trials

Erector Spinae Plane Block for Video-assisted Thoracoscopic Surgery

Start date: September 1, 2019
Phase: Phase 3
Study type: Interventional

Video-Assisted Thoracoscopic Surgery (VATS) is a minimally invasive surgery that utilizes camera based scopes and specialized instruments through keyhole sized ports to remove lesions in the thoracic cavity. Despite reduced surgical trauma compared to the traditional thoracotomy approach, patients continued to experience moderate to severe postoperative pain. Pain medication such as opioids is commonly utilized for postoperative pain control but is associated with side effects. The use of nerve blocks, such as the recently described erector spinae plane block (ESPB) has been shown in case reports to reduce pain and thus has the potential to improve patient recovery and decrease the risk of pulmonary complication. This study aims to investigate the analgesic effect of ESPB in managing pain following VATS.