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NCT ID: NCT05309070 Recruiting - Clinical trials for Burning Mouth Syndrome

The Efficacy of N-acetyl-cysteine in the Treatment of Burning Mouth Syndrome

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study was to examine the efficacy of N-acetyl cysteine in the treatment of burning mouth syndrome. A control group of patients with burning mouth syndrome will receive a placebo. The effect of the therapy will be monitored with the help of the visual-analogue scale (VAS) and the oral health-related quality of life questionnaire (OHIP-14).

NCT ID: NCT05308264 Recruiting - Clinical trials for Low Risk Myelodysplastic Syndromes

Study of R289 in Participants With Lower-risk Myelodysplastic Syndromes (LR MDS)

Start date: September 12, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Phase 1b Study of R289 in Participants with Lower-risk Myelodysplastic Syndromes (LR MDS)

NCT ID: NCT05306548 Recruiting - Clinical trials for Carpal Tunnel Syndrome

A Norwegian Trial Comparing Treatment Strategies for Carpal Tunnel Syndrome

NOR-CACTUS
Start date: April 8, 2022
Phase: Phase 4
Study type: Interventional

Carpal tunnel syndrome (CTS) causes numbness and pain in the hand and arm, and is an important cause of work absence and disability. The aim of the NOR-CACTUS Trial is to compare outcomes of a treatment strategy where the initial treatment is up to two ultrasound-guided corticosteroid injections, followed by scheduled clinical assessment of treatment effect, and subsequent surgery if needed, to a treatment strategy where surgery is the first-line treatment. Participants will be randomized to one of the treatment strategies, and followed up for two years after start of the study intervention. Outcomes will include patient-reported, clinical, functional and neurophysiological measures, and health-economic aspects. The hypothesis of the study is that there is no difference between the two treatment groups in the percentage of patients with a satisfactory symptom relief (treatment success) one year after the initial therapeutic intervention.

NCT ID: NCT05306080 Recruiting - HLH Clinical Trials

Tadekinig Alfa (IL-18BP) Rescue Therapy for CAR T Cell Related Cytokine Release Syndrome (CRS) and HLH-like Syndrome

Start date: April 17, 2022
Phase: Early Phase 1
Study type: Interventional

This is a pilot, open-label study to assess the safety and feasibility of using investigational drug(s) as rescue therapies for CAR T cell related CRS and HLH-like syndrome (CRHLS).

NCT ID: NCT05305898 Recruiting - Clinical trials for Acute Coronary Syndrome

"MetCool ACS"- Metformin "Cooling" Effect on Metformin-naive Patients Treated With PCI Because of Acute Coronary Syndrome

Start date: February 8, 2022
Phase: Phase 3
Study type: Interventional

The aim of the study is the evaluation of the effect of metformin among the patients without diabetes, on the incidence of reintervention, unplanned revascularization, after full percutaneous coronary revascularization as a result of the first episode of the acute coronary syndrome (ACS).

NCT ID: NCT05305677 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Effect of NMN (Nicotinamide Mononucleotide) on Polycystic Ovary Syndrome

NMN
Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to understand the effect of Nicotinamide mononucleotide (NMN) on patients with polycystic ovary syndrome.

NCT ID: NCT05305482 Recruiting - Clinical trials for Acute Coronary Syndrome

DCS Versus DES for One-month DAPT in Patients With ACS: ONE-PASS Trial

ONE-PASS
Start date: August 10, 2022
Phase: N/A
Study type: Interventional

To test whether the polymer-free drug-coated stent (DCS) BioFreedom is noninferior to the biodegradable polymer drug-eluting stent (DES) Ultimaster in terms of 1-year patient-oriented composite endpoint (POCE, composite of all-cause mortality, any MI, or any revascularization) in a setting of 1-month dual-antiplatelet therapy (DAPT) strategy (1-month DAPT followed ticagrelor monotherapy) after acute coronary syndrome.

NCT ID: NCT05302531 Recruiting - Clinical trials for Short Bowel Syndrome

Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome

GRAAL
Start date: December 9, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the drug absorption of oral antibiotics in patients with short bowel syndrome.

NCT ID: NCT05293769 Recruiting - Clinical trials for Irritable Bowel Syndrome

Reliability of a Food Frequency Questionnaire in the Assessment of Dietary Intake Including FODMAPs in Different Populations, and Relationship With IBS Symptoms and the Degree of Self-assessed Physical Activity

Start date: October 15, 2022
Phase:
Study type: Observational

During an online assessment participants will fill in questionnaires evaluating demographic data, psychological variables, the degree of self-assessed physical activity and symptoms of irritable bowel. Dietary intake will be assessed by a newly developed food frequency questionnaire (FFQ) and a 4 days food diary. In order to validate the FFQ in different populations, participants will be recruited from university students, staff of UZ Brussel and VUB, and from the community by advertisement (including social media). IBS patients will be recruited from the gastro-enterology outpatient clinic.

NCT ID: NCT05293184 Recruiting - Angelman Syndrome Clinical Trials

The Global Angelman Syndrome Registry

GASR
Start date: September 28, 2016
Phase:
Study type: Observational [Patient Registry]

The Global Angelman Syndrome Registry is an online patient organisation driven registry to collect information about the natural history of children and adults with Angelman Syndrome. The registry will facilitate 1) recruitment for clinical trials into therapies and interventions to benefit participants with Angelman Syndrome and their families, and 2) advancement of research and best standards of care for Angelman Syndrome. The registry is currently available in English, Spanish, Traditional Chinese, Italian, Polish, Hindi, and Brazilian Portuguese.