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Syndrome clinical trials

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NCT ID: NCT05977179 Not yet recruiting - Fatigue Clinical Trials

Dietary Intervention to Mitigate Post-Acute COVID-19 Syndrome

Long-COVIDiet
Start date: September 1, 2024
Phase: N/A
Study type: Interventional

The primary objective of this study is to conduct a 16-week randomized controlled trial aimed at investigating the effectiveness of the Whole-Diet Approach when following a healthy US-style diet rich in anti-inflammatory properties. The study will focus on evaluating its impact on reducing symptoms related to Post-Acute Sequelae of SARS-CoV-2 Infection (PACS) in adults aged 50 years and older. The main research questions this study aims to answer are: 1. Does adhering to a healthy US-style diet, which is abundant in anti-inflammatory properties, effectively mitigate fatigue symptoms in adults with PACS? 2. Does adhering to a healthy US-style diet, which is abundant in anti-inflammatory properties, effectively mitigate declines in muscle function and physical performance in adults with PACS? At the beginning of the study, eligible participants will be randomly assigned to either the Dietary Intervention Group, where they will receive personalized dietary plans and weekly sessions, or the Attention Control Group, where they will attend general health sessions on a weekly basis as well. This research intends to shed light on the potential benefits of the Whole-Diet Approach and its role in ameliorating PACS-related symptoms among older adults. By comparing the outcomes of the two groups, we hope to gain valuable insights into the effectiveness of this dietary intervention in improving the quality of life for individuals dealing with PACS.

NCT ID: NCT05976841 Recruiting - Clinical trials for Ehlers-Danlos Syndrome, Vascular Type

SEDVasc (RaDiCo Cohort) (RaDiCo-SEDVasc)

Start date: December 5, 2016
Phase:
Study type: Observational

The goal of this observational study is to describe the natural course of vascular Ehlers-Danlos syndrome, in particular the order of appearance of different types of complications (arterial, digestive, pulmonary and uterine).

NCT ID: NCT05976308 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Efficacy of Bushen Huatan Decoction in the Treatment of Polycystic Ovary Syndrome

Start date: September 1, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Polycystic ovary syndrome (PCOS) is a common reproductive disease associated with endocrine and metabolic disorders. Some studies have shown that Chinese herbal medicine is beneficial for PCOS, but the efficacy of Chinese herbal medicine in the treatment of PCOS is not clear, because the quantity of pre-clinical data was limited and the quality of clinical evidence was variable. Therefore, this randomized double-blind placebo-controlled trial aim to evaluate the efficacy of Chinese herbal medicine (Bushen Huatan Decoction) in women with PCOS.

NCT ID: NCT05976295 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Efficacy of Jianpi Qushi Huatan Decoction in the Treatment of Polycystic Ovary Syndrome

Start date: August 31, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Polycystic ovary syndrome (PCOS) is a common reproductive disease associated with endocrine and metabolic disorders. Some studies have shown that Chinese herbal medicine is beneficial for PCOS, but the efficacy of Chinese herbal medicine in the treatment of PCOS is not clear, because the quantity of pre-clinical data was limited and the quality of clinical evidence was variable. Therefore, this randomized double-blind placebo-controlled trial aim to evaluate the efficacy of Chinese herbal medicine (Jianpi Qushi Huatan Decoction) in women with PCOS.

NCT ID: NCT05975684 Recruiting - Rumination Syndrome Clinical Trials

Baclofen for Children With Rumination Syndrome

Start date: January 31, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to learn about baclofen in pediatric patients with rumination syndrome. The main question it aims to answer is whether baclofen is effective in treating children with rumination syndrome. Participants will be asked to take baclofen or placebo for 4 weeks and fill out surveys regarding symptoms.

NCT ID: NCT05973708 Completed - Clinical trials for Iliotibial Band Syndrome

Comparative Effects of Clamshells and Frog Pump Exercises

Start date: October 5, 2023
Phase: N/A
Study type: Interventional

Iliotibial band syndrome is where a tendon called iliotibial band gets irritated or swollen from rubbing against hip or knee when it gets too tensed. Iliotibial band (ITB) syndrome (ITBS) is the most common cause of lateral knee pain among athletes who are involved in sports that require continuous running or repetitive knee flexion and extension. The incidence ranges from 1.6% to 12% in runners. The aim of the study is to compare the effects of clamshells and frog pump exercises on gluteus medius strengthening and lower extremity function in runners with iliotibial band syndrome.

NCT ID: NCT05973682 Completed - Clinical trials for Upper Cross Syndrome

Effects of Post Isometric Relaxation With Scapular Stabilization Exercises

Start date: October 5, 2023
Phase: N/A
Study type: Interventional

The levator scapulae is an important postural muscle that tends to shorten or become tight because of overactivity and bad posture, leading to neck and shoulder pain. Levator scapulae syndrome is usually caused by the poor shoulders posture as rounded shoulders as sitting at a computer hunched. It is exacerbated by sustained neck postures, neck movements or levator scapulae muscle palpation. The aim of study will be to determine the effects of post isometric relaxation with scapular stabilization exercises on pain, disability and range of motion in patients with levator scapulae syndrome.

NCT ID: NCT05973175 Recruiting - Clinical trials for Polycystic Ovary Syndrome

REFUEL PCOS Study 1

REFUEL-PCOS
Start date: August 1, 2023
Phase:
Study type: Observational

Polycystic Ovary Syndrome (PCOS) affects 10% of all women, and it usually co-exists with high levels of male pattern hormones (also termed androgens). Women with PCOS are at increased risk of metabolic complications such as diabetes, non-alcoholic fatty liver disease, high blood pressure and heart disease. However, very little is understood about how androgen excess results in increased metabolic complications observed in women with PCOS. The main aims of the REFUEL PCOS study are to compare markers of energy metabolism in women with PCOS to those without PCOS. This will allow the investigators to better understand metabolic risk by examining the relationship between androgen excess and energy metabolism. Skeletal muscle is an important site of energy metabolism, and emerging theories are that androgen excess impairs skeletal muscle energy balance and increases the risk of complications. Based on these emerging theories, the investigators want to investigate the effects of androgens on muscle energy metabolism. The investigators will also examine whether certain blood and urine result patterns can help identify differences in muscles energy metabolism and which women are at the highest risk of metabolic complications. This research will give insight into the metabolic risk associated with PCOS and treat and, where possible, prevent the development of metabolic disease in affected women.

NCT ID: NCT05972928 Not yet recruiting - Clinical trials for Polycystic Ovary Syndrome

Effect of Sitagliptin on Polycystic Ovarian Syndrome Patients

Start date: July 30, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The Study aims to determine the proposed positive influence of Sitagliptin in manipulating hormonal , metabolic and inflammatory parameters in the treatment of Polycystic ovary syndrome and subsequent infertility

NCT ID: NCT05972837 Recruiting - Clinical trials for Myofascial Pain Syndrome of Neck

Effects of Home-based Surface Electrical Stimulation for Patients With Cervical Myofascial Pain Syndrome

Start date: August 4, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the developed home-based surface electrical stimulation program to the controls in computer office workers with MPS.