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Syndrome clinical trials

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NCT ID: NCT01192672 Completed - Clinical trials for Irritable Bowel Syndrome

Use of Expressive Writing in Irritable Bowel Syndrome (IBS)

Start date: September 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to test whether disease-related expressive writing is effective in the treatment of Irritable Bowel Syndrome (IBS).

NCT ID: NCT01192503 Terminated - Clinical trials for Restless Legs Syndrome

Safety and Efficacy of Rasagiline in Restless Legs Syndrome

RAS-RLS
Start date: September 2010
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to find out if rasagiline improves RLS symptoms. We also want to make sure rasagiline is safe to give people with RLS.

NCT ID: NCT01191177 Withdrawn - Liver Disease Clinical Trials

Investigational Study of Oral Fish Oil in Treating Parenteral Nutrition Associated Liver Disease

Start date: January 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate the usefulness of oral fish oil(Lovaza)in normalizing liver function in patients who have parenteral nutrition associated liver disease. The investigators believe that patients who take oral fish oil will normalize liver function faster than those who do not

NCT ID: NCT01190891 Active, not recruiting - Clinical trials for Shoulder Impingement Syndrome

Physical Therapy Versus Steroid Injection for Shoulder Impingement Syndrome

Start date: May 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate and compare the short and long-term effectiveness of two common interventions, manual physical therapy versus corticosteroid injection, for the treatment of shoulder impingement syndrome.

NCT ID: NCT01190358 Completed - Metabolic Syndrome Clinical Trials

Grape Seed Extract and Postprandial Oxidation and Inflammation

GSEMetS
Start date: August 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether taking grape seed extract prior to eating a high fat meal will reduce the inflammatory response in people with the metabolic syndrome.

NCT ID: NCT01189994 Recruiting - Fibromyalgia Clinical Trials

Trial of Acupuncture in the Treatment of Fibromyalgia

Start date: September 2010
Phase: N/A
Study type: Interventional

Fibromyalgia is a medical condition characterized by musculoskeletal pain, fatigue, sleep disturbances and depression. It affects population at a socioeconomically active age and represents a burden for the patients and the health care system due to its personal and functional implications. At this moment, there is no completely effective treatment for fibromyalgia, and acupuncture has been a promising alternative. This trial aims to evaluate if addition of acupuncture to standard care represents an improvement in comparison with standard care only. Thus, patients enrolled in this trial will be randomly allocated into one of two groups: group A, who besides standard treatment will receive 12 sessions of acupuncture; and group B, who will receive standard care with monthly orientation sessions for the same period. Patients will be evaluated at baseline, after completion of acupuncture treatment or orientation, and after an additional 12-week follow up. Evaluation will be based on diaries of pain and medication, and standard scales of pain, quality of life and disability.

NCT ID: NCT01189669 Completed - Clinical trials for Polycystic Ovary Syndrome

n-3 Polyunsaturated Fatty Acids (PUFA) Supplementation in Young Women With Polycystic Ovary Syndrome (PCOS)

Start date: September 2007
Phase: N/A
Study type: Interventional

This is a dietary intervention study designed to assess the impact of long chain (LC) n-3 polyunsaturated fatty acids (PUFA) in young women with polycystic ovary syndrome (PCOS). Considering that LC n-3 PUFA have been reported to have a beneficial affect on many of the adverse metabolic and hormonal aspects of PCOS, it was hypothesised that dietary supplementation with LC n-3 PUFA would have a beneficial therapeutic impact.

NCT ID: NCT01189162 Recruiting - Clinical trials for Respiratory Distress Syndrome

High Flow Nasal Cannula (HFNC) Versus Nasal Intermittent Mandatory Ventilation (NIMV)for Respiratory Distress Syndrome (RDS): a Randomized, Controlled, Prospective Study

Start date: January 2010
Phase: N/A
Study type: Interventional

The investigators hypothesize that while the extremely low birthweight (ELBW) infants (<1000 g) may need NIMV for the treatment of RDS, larger infants or the smaller ones post extubation may enjoy the comfort benefits associated with HFNC while getting coparable respiratory support to NIMV.

NCT ID: NCT01188291 Completed - Clinical trials for Obstructive Sleep Apnea

Retinal Nerve Fiber Layer Thickness Measurements in Patients With Sleep Apnea Syndrome

Start date: September 2007
Phase: N/A
Study type: Observational

The purpose of this study was to measure the retinal nerve fiber layer (RNFL) thickness in eyes of Obstructive Sleep Apnea/hypopnea syndrome (OSAHS) using optical coherence tomography (OCT), and assess whether it is decreased. The investigators then compared the results with healthy subjects database of RNFL thickness from another retrospective study.

NCT ID: NCT01188005 Recruiting - Clinical trials for Obstructive Sleep Apnea Syndrome

Inflammatory Mediators in Obstructive Sleep Apnoea Syndrome; Mechanisms of Production and the Effect of Long Term Antioxidants Administration

Start date: August 2010
Phase: N/A
Study type: Interventional

Obstructive Sleep Apnea Syndrome (OSAS) is associated with elevated plasma levels of IL-6 and TNF-α, which cannot be accounted for by obesity (Vgontzas et al Sleep Med Rev 2005;9:211-24, Ciftci et al Cytokine 2004;28:87-91]. Obstructive apneas-hypopneas are accompanied by strenuous diaphragmatic contractions before the ensuing arousals and re-establishment of airway patency. We have shown that strenuous diaphragmatic contractions induced by resistive loading lead to elevated plasma levels of IL-6, TNF-α, and IL-1β (Vassi-lakopoulos et al AJRCCM 2002;166:1572-8) with concomitant up-regulation of the cytokines within the diaphragmatic myofibers (Vassilakopoulos et al AJRCCM 2004;170:154-61). OSAS patients exhibit frequent episodes of hypoxemia during the night. Loaded breathing is a form exercise for the respiratory muscles, and both acute and chronic hypoxia lead to an augmented plasma IL-6 response to exercise compared to normoxia (Lundby et al Eur J Appl Physiol 2004;91:88-93). In OSAS, monocytes have oxidative stress (Dyugovskaya et al AJRCCM 2002;165:934-9) and produce more cytokines (TNF-α) in vitro (Minoguchi et al Chest 204;126:1473-9). Hypothesis #1: plasma levels of IL-6 and TNF-α are increased during the night in OSAS patients secondary to the intermittent strenuous diaphragmatic contractions and the episodes of hypoxia-reoxygenation associated with the obstructive apneas-hypopneas. Hypothesis #2: monocytes from sleep apnea patients, exhibit augmented intracellular expression of IL-6 and TNF-α during the night. Hypothesis #3: Oxidative stress is a stimulus for cytokine upregulation in OSAS.