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Syndrome clinical trials

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NCT ID: NCT01348087 Completed - Fragile X Syndrome Clinical Trials

Long-term, Safety, Tolerability and Efficacy Study of AFQ056 in Adult Patients With Fragile X Syndrome

Start date: August 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to generate long-term safety, tolerability and efficacy data for AFQ056 in eligible adult patients with FXS who have participated in the CAFQ056A2212 core study and patients who have participated in the previous proof-of-concept study CAFQ056A2204.

NCT ID: NCT01347944 Completed - Clinical trials for Myelodysplastic Syndrome

MORE - Monitoring Revlimid - Collecting of Patient Information From Myelodysplastic Syndrome (MDS) Italian National Registry

MORE
Start date: January 1, 2011
Phase:
Study type: Observational

The purpose of this study is to collect clinical and laboratory data for patients affected by intermediate 1 and low risk Myelodysplastic Syndrome (MDS) associated by deletion 5q who were prescribed Revlimid from 31October 2008 to present. Revlimid is available in Italy for these patients since October 2008 based on a local disposition of the Italian Drug Agency (AIFA) issued according to a National law named 648/96.

NCT ID: NCT01347346 Completed - Clinical trials for Wiskott-Aldrich Syndrome

Gene Therapy for WAS

Start date: May 2011
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase I/II study to evaluate the safety and efficacy of Hematopoietic Stem Cell genetherapy for the Wiskott-Aldrich Syndrome.

NCT ID: NCT01347242 Completed - Clinical trials for Wiskott-Aldrich Syndrome

Gene Therapy for Wiskott-Aldrich Syndrome (WAS)

Start date: March 2011
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase I/II study to evaluate the safety and efficacy of Hematopoietic Stem Cell genetherapy for the Wiskott-Aldrich Syndrome.

NCT ID: NCT01346007 Active, not recruiting - Clinical trials for Idiopathic Nephrotic Syndrome

Study of 7-valent Pneumococcal Conjugate Vaccine in Children With Idiopathic Nephrotic Syndrome

Start date: January 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether 7-valent pneumococcal conjugate vaccine safely induces immune responses and immunological memory in children with idiopathic nephrotic syndrome in remission.

NCT ID: NCT01345305 Completed - Clinical trials for Sturge-Weber Syndrome

Biomarker Development in Sturge-Weber Syndrome

Pilot
Start date: July 2010
Phase:
Study type: Observational

This is a study of 40 individuals with Sturge-Weber Syndrome (SWS) brain and/or eye involvement. It will examine the test-retest reliability of the following clinical tests: 1. Quantitative EEG 2. Transcranial Doppler 3. Medical Rehabilitation Scales 4. Optical Coherence Tomography

NCT ID: NCT01344811 Completed - Obesity Clinical Trials

Effects of Telemonitoring Service for Obesity Care

Smart-OB
Start date: January 2011
Phase: N/A
Study type: Interventional

A randomized, open, parallel, multi-center trial to evaluate weight loss efficacy of Smart Care Service in obese patients with metabolic syndrome.

NCT ID: NCT01342744 Recruiting - Metabolic Syndrome Clinical Trials

Metformin in Postmenopausal Women With Metabolic Syndrome

Start date: April 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the effects of metformin on cardiovascular risk factors in postmenopausal women with metabolic syndrome.

NCT ID: NCT01342718 Completed - Clinical trials for Irritable Bowel Syndrome

Effect of Herbal Extract Granules Combined With Probiotics on Irritable Bowel Syndrome With Diarrhea

Start date: April 2011
Phase: N/A
Study type: Interventional

The aims of this study are to investigate the effect of famous herbal formula extract and probiotics on irritable bowel syndrome with diarrhea, and to determine whether these two experimental items affect intestinal permeability and the composition of intestinal microbiota.

NCT ID: NCT01342068 Completed - Clinical trials for Thoracic Outlet Syndrome

The Effectiveness of Diagnosis and Treatment of Thoracic Outlet Syndrome

Start date: June 2011
Phase: N/A
Study type: Observational

Thoracic Outlet Syndrome (TOS) is a condition causing numbness, tingling and weakness in patient's upper limbs. Symptoms are due to compression and restriction of the nerves and blood vessels (neurovascular bundle) that extend from the neck into the upper limb exerted by a patient's various anatomical structures. Neurovascular bundle compression can result in decreased nerve conduction and blood flow through the arteries supplying structures downstream from the restricted site. These anatomical restrictions include tight scalene muscles in the neck, tightened pectorialis minor muscle in the chest and extra ribs growing from the C7 vertebra. TOS can be diagnosed by using special tests designed to re-elicit neurovascular bundle compression. Upon obtaining a positive test, the patient can undergo osteopathic manipulative treatments (OMT) to change the anatomical restrictions allowing for a decrease of symptoms and even eradication of the syndrome altogether. Although diagnosis and treatment of TOS is common in osteopathic medicine, the effectiveness of the diagnostic special tests and treatment has not been thoroughly investigated. This study aims to examine the effectiveness of the special tests (Adson's, Wright's hyperabduction and Halstead maneuver) in diagnosing a change in blood flow through the arteries of the upper arm compared to evaluation with Doppler ultrasound to measure blood flow while the tests are performed. Patients with positive tests will be treated with OMT including myofascial release, soft tissue, and articulation to relieve restricting structures. Upon completion of treatment, the special tests will be performed again along with the Doppler ultrasound to measure blood flow through blood vessels. Results then are analyzed statistically for significance of the ability correctly diagnose and treat TOS symptoms. Results from this study will contribute towards the validity of teaching special tests in osteopathic medical schools and allow for a non-invasive treatment protocol for patients with TOS.