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Syndrome clinical trials

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NCT ID: NCT01578005 Completed - Clinical trials for Acute Coronary Syndrome

IVUS Assessment of Atheroma Burden After Acute Coronary Syndrome

OPTIVUS
Start date: March 2011
Phase:
Study type: Observational

Coronary angioplasty is rather frequently performed in such situations, presumably because, changes in the atherosclerotic plaque under drug treatment, have remained poorly described so far. Intravascular ultrasound (IVUS) enables a precise description of coronary atheroma, better than the one provided by coronary angiography.

NCT ID: NCT01577017 Completed - Clinical trials for Polycystic Ovarian Syndrome

The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)

Start date: May 2008
Phase: Phase 3
Study type: Interventional

As both medications i.e. CC and letrozole have been shown to be effective in inducing ovulation in PCOS patients, this study was performed in order to evaluate which regime (whether CC or letrozole) is the best to be used as the first line treatment for PCOS patients with infertility for local population. The best regime will therefore could be included in the protocol of management of infertility patients with PCOS so that the quality of patients' care could be improved.

NCT ID: NCT01576705 Completed - Down Syndrome Clinical Trials

Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children

ACTHYF
Start date: April 2, 2012
Phase: Phase 3
Study type: Interventional

Evaluation of the following in very young children with Down syndrome: - the efficacy of systematic treatment with L-thyroxine at controlled doses (clinically and by ultrasensitive thyreostimulating hormone (TSH) assay), - the efficacy of systematic folinic acid treatment at a dose of 1 mg/kg/o.i.d, - any interaction between these two treatments.

NCT ID: NCT01576367 Completed - Clinical trials for Familial Cold Autoinflammatory Syndrome

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Start date: January 16, 2012
Phase: Phase 3
Study type: Interventional

This trial will provide long-term safety, efficacy and tolerability of ACZ885 in CAPS patients that completed the CACZ885D2307 study

NCT ID: NCT01576003 Completed - Nutrition Clinical Trials

Enteral Glutamine in Reducing Bloodstream Infections in Short Bowel Syndrome Infants

Start date: April 2012
Phase: N/A
Study type: Interventional

The purpose of this research study is to evaluate the effects (good and bad) of supplementation with Glutamine to that of a placebo (L-alanine), on your child and their Short Bowel Syndrome. Researchers are doing this study to see if the addition of Glutamine to oral/tube feeding (nutrition therapy) will work better by preventing bloodstream infections, improving growth, and/or changing the make-up of bacteria in your child's intestine. Glutamine is approved by the FDA for use in adults with Short Bowel Syndrome. In this study, the investigators will be assessing how well Glutamine affects Short Bowel Syndrome in children.

NCT ID: NCT01573858 Completed - Infertility Clinical Trials

Acupuncture and Clomiphene Citrate on Live Birth in Anovulatory Women With Polycystic Ovary Syndrome

PCOSAct
Start date: July 6, 2012
Phase: N/A
Study type: Interventional

The objectives of the present trial are to test the following three hypotheses in anovulatory women with PCOS: 1. Acupuncture protocol 1 plus CC (Arm A) is more likely to result in live birth than acupuncture protocol 2 combined with CC (Arm B), 2. Acupuncture protocol 2 plus CC (Arm B) is more likely to result in live birth than acupuncture protocol 1 plus placebo (Arm C), 3. Acupuncture protocol 1 plus placebo (Arm C) is more likely to result in live birth than acupuncture protocol 2 plus placebo (Arm D).

NCT ID: NCT01572636 Terminated - Hurler Syndrome Clinical Trials

Laronidase (Aldurazyme TM) Enzyme Replacement Therapy With Hematopoietic Stem Cell Transplant for Hurler Syndrome

Start date: March 28, 2012
Phase:
Study type: Observational

This is a standard of care treatment guideline for patients with the diagnosis of mucopolysaccharidosis type IH (MPS I, Hurler syndrome) who are being considered as candidates for first hematopoietic stem cell transplantation (HSCT) according to a University of Minnesota myeloablative HSCT protocol.

NCT ID: NCT01571947 Completed - Metabolic Syndrome Clinical Trials

Acute Effects of Dietary Fats and Carbohydrate in Subjects With Metabolic Syndrome

Start date: November 2011
Phase: N/A
Study type: Interventional

There is increasing evidence suggests that elevated levels of postprandial triacylglycerol (TAG)-rich lipoproteins may promote the development of cardiovascular diseases (CVD). A prolonged and elevated postprandial lipemia is associated with increased risk of CVD by a variety of mechanisms such as insulin resistance, inflammation, endothelial dysfunction and oxidative stress. However, current evidence on the acute effects of type of fats on postprandial insulinaemia, gastrointestinal peptide secretion, inflammatory response, as well as satiation are limited and inconsistent, in particular in metabolic syndrome population in Asian. Hence, this study aimed to investigate the postprandial effects of high fat meals enriched with i) palm olein, ii) high oleic sunflower oil, and iii) high linoleic sunflower oil, compared with a low fat/high carbohydrate meal, in 30 subjects with metabolic syndrome.

NCT ID: NCT01571648 Completed - Clinical trials for Myelodysplastic Syndromes

A Phase 1 Study to Evaluate the Pharmacokinetics and Tolerability of Oral Azacitidine in Japanese Patients With Myelodysplastic Syndromes

Start date: April 1, 2012
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the tolerability of oral azacitidine in the treatment of patients with Myelodysplastic Syndromes (MDS).

NCT ID: NCT01570153 Completed - Clinical trials for Acute Decompensated Heart Failure

Biomonitoring and Cardiorenal Syndrome in Heart Failure(BIONICS-HF) Trial

BIONICS-HF
Start date: March 2012
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the ability of a non-invasive monitor that measures how much fluid is in the body as well as various blood tests for their ability to predict worsening kidney function in patients with heart failure.