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Syndrome clinical trials

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NCT ID: NCT02374775 Active, not recruiting - Clinical trials for Myocardial Infarction

Exploring the MEchanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and computationaL Fluid Dynamic

EMERALD
Start date: September 2014
Phase: N/A
Study type: Observational

The EMERALD trial is a multinational, multicenter study. The patients presented with AMI/definite evidence of plaque rupture and had underwent coronary CT angiography from 1 month to 2 year prior to the event will be retrospectively searched. Plaques in the non-culprit vessels will be regarded as internal control to the ruptured plaque in the culprit vessel.

NCT ID: NCT02374125 Recruiting - Clinical trials for Subacromial Impingement Syndrome

Teres Major Muscle and Subacromial Impingement Syndrome

Start date: November 2014
Phase: N/A
Study type: Interventional

There is not a clear understanding of the origin of symptoms perceived by patients with impingement of the soft tissue structures of the subacromial space. Tendinopathy, tendon rupture or other pathologies, are present in asymptomatic subjects and subjects with symptoms and structural integrity can also be found. Patients diagnosed with subacromial impingement syndrome frequently have myofascial trigger points in the teres major muscle. Travell and Simons reported that the symptoms caused by trigger points in this muscle are similar to those experienced by patients diagnosed with impingement syndrome, but a literature search provides few results regarding relationship between subacromial impingement syndrome and presence of myofascial trigger points in the teres major muscle. This study aims to provide evidence of the results that can be obtained with a specific approach of teres mayor muscle by two manual techniques, Trigger Point Pressure Release and Diacutaneous Fibrolysis, in subjects with subacromial impingement syndrome, a condition that still representing both a diagnostic and therapeutic challenge. Secondary objective is to compare the outcomes between both techniques to select for each patient the most appropriate to their needs and characteristics.

NCT ID: NCT02374112 Active, not recruiting - Clinical trials for Chronic Fatigue Syndrome

Creatine Supplementation in Chronic Fatigue Syndrome

CREFAS
Start date: January 2016
Phase: N/A
Study type: Interventional

This study evaluates the effectiveness of medium-term supplementation with creatine to improve clinical outcomes in well-defined adult CFS population. Half of the participants will receive creatine while the other half will receive placebo.

NCT ID: NCT02371499 Completed - Clinical trials for Irritable Bowel Syndrome

Effect of Lactobacillus Casei DG (Enterolactis Plus®) in Patient With Irritable Bowel Syndrome: a Pilot Study

Start date: December 2014
Phase: N/A
Study type: Interventional

The aim of the study is to collect data for the assessment of the Lactobacillus casei DG (Enterolactis plus®) effect on overall abdominal pain/discomfort, symptoms and gut microbiota composition in patients with Irritable Bowel Syndrome.

NCT ID: NCT02371135 Active, not recruiting - Lynch Syndrome Clinical Trials

Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes

Start date: February 2015
Phase:
Study type: Observational

The purpose of this study is to understand the role bacteria that normally live in the colon may play in colorectal cancer risk, in addition to the hereditary risk to colorectal cancer. The investigators will collect stool specimens as well as additional colon biopsy specimens during the patient's scheduled colonoscopy procedure. The investigators will also collect a questionnaire about diet and lifestyle. The samples will be used to study the impact of diet on naturally-occurring oral and gut bacteria and their influences on human health including risk of cancer.

NCT ID: NCT02370888 Terminated - Clinical trials for Myelodysplastic Syndromes

Lenalidomide After Allo-Hematopoietic Cell Transplant (HCT) in Acute Myelogenous Leukemia (AML) and Myelodysplastic Syndromes (MDS) Subjects With Minimal Residual Disease

UF-BMT-MRD-101
Start date: May 16, 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the maximum tolerated dose, dose limiting side effects, and the safety of increasing doses of lenalidomide in patients with AML and MDS who have a small amount of detectable disease after allogeneic stem cell transplant.

NCT ID: NCT02370550 Recruiting - Sjogren's Syndrome Clinical Trials

Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome

CTRIPS
Start date: March 2015
Phase: Phase 4
Study type: Interventional

The purpose of this large multicenter, randomized, double-blinded, controlled clinical study is to investigate the efficacy and safety of Cyclosporin A for primary Sjogren's syndrome associated pneumonitis(pSS-IP), which has important implications for the establishment of standardized diagnosis and treatment of pSS-IP.

NCT ID: NCT02370225 Completed - Sjogren's Syndrome Clinical Trials

Aerobic Exercise in Primary Sjögren's Syndrome

AEPSS
Start date: March 2015
Phase: N/A
Study type: Interventional

The purpose of this sudy is to investigate the effects of a regular aerobic exercise on aerobic capacity, fatigue, depression, quality of life, perception of symptoms and disease activity in women with pSS.

NCT ID: NCT02370121 Completed - Metabolic Syndrome Clinical Trials

Effect of Gymnema Sylvestre on Metabolic Syndrome and Insulin

Start date: February 2013
Phase: Phase 2
Study type: Interventional

Gymnema sylvestre has demonstrated promising effects in the treatment of obesity, dyslipidemia, hypertension, insulin secretion, among others. The above mentioned findings show that Gymnema sylvestre has an excellent potential for the prevention and treatment of metabolic syndrome.

NCT ID: NCT02368379 Completed - Clinical trials for Adrenal Insufficiency

Diagnosis of Central Adrenal Insufficiency in Patients With Prader-Willi Syndrome

Start date: March 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine presence of central adrenal insufficiency in children with Prader Willi Syndrome using low dose (1 mcg) ACTH stimulation test compared to results of overnight metyrapone test.