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Syndrome clinical trials

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NCT ID: NCT02896270 Recruiting - Clinical trials for Focal Segmental Glomerulosclerosis

Valproic Acid for Idiopathic Nephrotic Syndrome

VAIN
Start date: October 2016
Phase: Phase 2/Phase 3
Study type: Interventional

The trial investigates the use of VPA (Valproic Acid) for the treatment of adult patients with biopsy proven idiopathic focal segmentel glomerulosclerosis (FSGS) or minimal change disease (MCD). VPA used as an add-on to steroids might induce clinical remission in a first category of patients and potentially reduce the dose of maintenance immunosuppression required to maintain remission thereafter. In a second category of patients VPA might allow the reduction or even cessation of immunosuppression while clinical remission is maintained.

NCT ID: NCT02895906 Completed - Clinical trials for 22q11.2 Deletion Syndrome

Safety and Efficacy Study of NFC-1 in Subjects Aged 12-17 Years With 22q11.2DS & Associated Neuropsychiatric Conditions

Start date: November 28, 2016
Phase: Phase 1
Study type: Interventional

This is a 5-week, multi-center, open-label, dose optimization trial in subjects aged 12-17 years with 22q11DS who have a diagnosis of anxiety disorder, and/or ADHD, and/or ASD. Approximately 12 subjects will be initiated, dose optimized, and maintained on NFC-1 over a period of 5 weeks.

NCT ID: NCT02895802 Completed - Down Syndrome Clinical Trials

Assessing the Feasibility of the Use of Visual Aids in Patient Education in Adults With Down Syndrome (DS)

Start date: August 2016
Phase: N/A
Study type: Interventional

Purpose: To assess the feasibility of using videos depicting people with DS to teach other adults with DS to perform healthy behaviors. Hypothesis: Videos of adults with DS performing healthy behaviors is a more effective way to promote healthy behaviors by adults with DS than other methods tested. This project will study whether videos showing a person with DS washing his hands correctly can improve hand washing by other adults with DS.

NCT ID: NCT02895191 Enrolling by invitation - Clinical trials for Acute Respiratory Distress Syndrome

The Safety and Dose Response Relationship of Ulinastatin for Acute Respiratory Distress Syndrome(ARDS)

Start date: August 2016
Phase: Phase 2
Study type: Interventional

Compared with placebo, evaluate the effects and safety of Ulinastatin(UTI) added to conventional treatment for ARDS; Evaluate the dose response relationship of Ulinastatin for ARDS.

NCT ID: NCT02893865 Completed - Clinical trials for Coronary Artery Disease

Evolution of Oxidative Stress in Coronary Patients With Moderate Sleep Apnea Syndrome After Treatment With Continuous Positive Airway Pressure

CardioX SAS
Start date: May 2016
Phase: N/A
Study type: Interventional

Published data indicate that obstructive sleep apnea syndrome (OSAS) worse the prognosis of coronary artery disease (CAD) and that oxidative stress can link this 2 diseases. Investigators hypothesise that oxidative stress decrease after 3 months of continuous positive airway pressure (CPAP) in this specific population. The results may have major implication in the comprehension of physiopathologic processes linking OSAS and CAD and in the treatment of OSAS in this specific population.

NCT ID: NCT02893280 Withdrawn - Clinical trials for Acute Coronary Syndrome

Acute Coronary Syndrome Sri Lanka Audit Project

ACSSLAP
Start date: April 2015
Phase: N/A
Study type: Observational

ACSSLAP is the first island wide audit project in Sri Lanka on ACS.

NCT ID: NCT02892903 Active, not recruiting - Clinical trials for Acute Coronary Syndrome

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment at the Time of Coronary Angiography Affect Management Strategy, Hospital Costs and Outcomes?

RIPCORD 2
Start date: September 2016
Phase: N/A
Study type: Interventional

A randomised controlled trial to compare two strategies for the investigation of coronary artery disease at the time of angiography. Patients will be randomised to conventional angiography or additional, routine pressure wire assessment - measuring fractional flow reserve (FFR) - in all main vessels judged as being of sufficient vessel calibre to allow percutaneous coronary intervention (PCI) (experimental arm).

NCT ID: NCT02891694 Completed - Clinical trials for Recurrent Corneal Erosion Syndrome

Metalloproteinases and Recurrent Corneal Erosion Syndrome

MERCURE
Start date: December 2, 2016
Phase:
Study type: Observational

Recurrent corneal erosion (RCE) syndrome can be observed either in the context of a dystrophy of the basement membrane or following corneal trauma. This syndrome is characterized by recurrent episodes of ocular pain more or less associated with localized separations between the outer epithelium and the epithelial basal lamina (basement membrane) because of anchorage abnormalities between these two corneal layers. This could be the result of an increased expression of metalloproteinases cleaving the hemidesmosomes which anchor epithelium to the basement membrane. The investigators hypothesis is that episodes of RCEs are favored by a hyper- expression of matricial metalloprotease 9 (MMP-9) induced by EMMPRIN and Galectin-3. The identification of such induction could lead to development of therapeutics inhibiting EMMPRIN and Galectin- 3 in the RCE syndrome.

NCT ID: NCT02891512 Completed - Clinical trials for Carpal Tunnel Syndrome

Very Low Frequency Magnetic Fields Versus the Supplement "Xinepa" in the Treatment of the Carpal Tunnel Syndrome

Start date: July 2015
Phase: N/A
Study type: Interventional

The purpose of the study is to determine the effectiveness of the treatment with very low frequency magnetic fields (ELF) on the reduction of pain and the relief of the associated signs such as sensitivity disorders that affect the first three fingers and half of the fourth finger of the hand in patients with carpal tunnel syndrome versus the supplement (= Xinepa).

NCT ID: NCT02891330 Completed - Dumping Syndrome Clinical Trials

Impact of an Educational Personalized Clinical Support Device Preventive and a Referent Nurse in Surgery for Obesity

IRCO
Start date: March 2, 2017
Phase: N/A
Study type: Interventional

The postprandial dumping syndrome is a frequent consequence of Roux-en-Y Gastric ByPass due to the rapid emptying of the stomach remnant in to the intestinal lumen. Dumping-related symptoms occur very early after eating (within 30 minutes), are not associated with concurrent hypoglycemia, and are most prominent in the early postoperative period. This syndrome very debilitating for the patient can be improved by dietary and nutritional recommendations. We hypothesize that a personalized approach based on dietary and nutritional recommendations conducted by a nurse would likely to decrease the frequency of dumping syndrome and improve the postoperative quality of life of patients in the early postoperative period.