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Syndrome clinical trials

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NCT ID: NCT04255537 Recruiting - Clinical trials for Acute Coronary Syndrome

Clinical Governance of Patients With Acute Coronary Syndrome in Italy

Start date: January 1, 2018
Phase:
Study type: Observational [Patient Registry]

This is a prospective, observational, multicenter study that enroll consecutive and all-comers patients hospitalized with a diagnosis of Acute Coronary Syndrome (ACS) at admission.

NCT ID: NCT04255186 Completed - Clinical trials for Shoulder Impingement Syndrome

Treatment Using 448 kHz CRMRF in Subacromial Syndrome.

CRMRF
Start date: February 3, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effectiveness of 448 kHz capacitive resistive monopolar radiofrequency in the treatment of subacromial syndrome.

NCT ID: NCT04252703 Terminated - Clinical trials for Cardiovascular Diseases

'MInimalist' or 'MOre Complete' Strategies for Revascularization in Octogenarians

Start date: May 13, 2020
Phase: N/A
Study type: Interventional

Older patients with co-morbidity are increasingly represented in interventional cardiology practice. They have been historically excluded from studies regarding the optimal management of NSTEACS. Though there are associated risks with invasive treatment, such patients likely derive the greatest absolute benefit from PCI. Small, though highly selective, studies suggest a routine invasive strategy may reduce the risk of recurrent myocardial infarction. The study aims to include, as far as possible, an 'all-comers' population of patients aged 80 and above to define the optimum amount of revascularization required to achieve good outcomes and satisfactory symptom relief for this challenging cohort of patients.

NCT ID: NCT04252586 Terminated - Rett Syndrome Clinical Trials

A Long-term Safety Study of Cannabidiol Oral Solution (GWP42003-P, CBD-OS) in Patients With Rett Syndrome

Start date: February 28, 2020
Phase: Phase 3
Study type: Interventional

This study will be conducted to evaluate the long-term safety of cannabidiol oral solution (GWP42003-P, CBD-OS) in participants with Rett syndrome.

NCT ID: NCT04252209 Completed - Sjogren's Syndrome Clinical Trials

the Effect of Mixture of Natural Products As Salivary Substitutes in Treatment Of Xerostomia

RCT
Start date: March 22, 2021
Phase: Phase 3
Study type: Interventional

evaluate the efficacy of natural herbal mixture of aloe vera gel, coconut oil and peppermint in comparison to the carboxy methyl cellulose on xerostomia in a sample of patients with Sjogren's syndrome.

NCT ID: NCT04252001 Not yet recruiting - Clinical trials for Growth Hormone Deficiency

Growing up With the Young Endocrine Support System (YESS!)

YESS
Start date: December 1, 2024
Phase: N/A
Study type: Interventional

Transition from paediatric to adult endocrinology is a challenge for adolescents, families and doctors. Up to 25% of young adults with chronic endocrine disorders are lost to follow-up ('drop-out') once the young adult moves out of paediatric care. Non-attendance and sub-optimal medical self-management can lead to serious and expensive medical complications. In a pilot study, adolescents suggested the use of e-technology to become more involved in the transition process. The investigators have designed and developed the YESS! game, a tool to help improve medical self-management in adolescents with chronic endocrine disorders. The hypothesis is that adolescents playing the YESS! game will show a larger increase in self-management score during the first year of transition and will have a lower drop-out rate at the adult endocrine outpatient clinic (OPC), compared to adolescents who do not play the game.

NCT ID: NCT04250051 Recruiting - Clinical trials for Refractory Acute Myeloid Leukemia

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

Start date: December 21, 2020
Phase: Phase 1
Study type: Interventional

This phase I trial studies the side effects and best dose of ivosidenib when given together with combination chemotherapy for the treatment of 1DH1 mutant acute myeloid leukemia that has come back (relapsed) or does not respond to treatment (refractory). Ivosidenib may stop the growth of cancer cells by blocking the IDH1 mutation and some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as fludarabine phosphate, cytarabine, and filgrastim, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving ivosidenib with combination chemotherapy may work better in treating patients with acute myeloid leukemia compared to chemotherapy alone.

NCT ID: NCT04250025 Recruiting - Clinical trials for Post Thrombotic Syndrome

Angioplasty-stenting vs Optimal Medical Treatment on Post-thrombotic Syndrome Reduction

EndoPTS
Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The project will highlight the potential benefit of endovascular therapy on post thrombotic syndrome reduction after proximal iliac DVT. There is actually not real standard of care for the treatment of this pathology. A clear evidence of efficacy of endovascular therapy will be of great benefit for both the patients and the healthcare system, and will provide new data for further international guidelines

NCT ID: NCT04247477 Completed - Acute Lung Injury Clinical Trials

Comparison of Different PEEP Titration Strategies Using Electrical Impedance Tomography in Patients With ARDS

DELTA
Start date: September 22, 2020
Phase: N/A
Study type: Interventional

The aim of the this study is to assess the short term physiological effects of 3 ventilation strategies for adult patients with ARDS admitted to intensive care unit. Two of those strategies are based on electrical impedance tomography (EIT) monitoring.

NCT ID: NCT04246775 Completed - Clinical trials for Anterior Resection Syndrome

Low Anterior Resection Syndrome and Rectal Irrigation Study

LARRIS
Start date: April 2015
Phase: N/A
Study type: Interventional

Prospective study assessing treatment acceptability and the impact of rectal irrigation on patients with low anterior resection syndrome (LARS) in terms of quality of life and bowel function.