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Syndrome clinical trials

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NCT ID: NCT04412395 Not yet recruiting - COVID-19 Clinical Trials

Clinical Assessment of Oral Lactoferrin as a Safe Antiviral and Immunoregulatory in Treating COVID-19 Disease

COVID-19_LF
Start date: February 1, 2022
Phase: Phase 2
Study type: Interventional

The aim of the study is to clinically use bovine Lf as a safe antiviral adjuvant for treatment and to assess the potential in reducing mortality and morbidity rates in COVID-19 patients. The study was approved by the ethical committee of the Egyptian Center for Research and Regenerative Medicine in 11-5-2020.

NCT ID: NCT04409600 Active, not recruiting - Clinical trials for Chronic Exertional Compartment Syndrome

Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)

Start date: November 5, 2020
Phase: Phase 2
Study type: Interventional

Chronic Exertional Compartment Syndrome (CECS) in the lower leg is a debilitating condition in highly active individuals. Pain occurs in 1 or several leg compartments upon an exertional activity, typically running, that quickly dissipates once the activity stopped. Surgical fasciotomy is the standard for treating lower leg CECS, but success is variable. Complications may occur post-surgery and there is a potential for a repeat procedure. Recovery times post-surgery also vary greatly. Conservative treatments, such as gait retraining and botulinum toxin injections, are emerging as non-surgical options for the treatment of CECS with success through published case reports and case series. This study aims to evaluate the use of these non-surgical treatment options for CECS in the anterior and lateral leg compartments with a follow up for at least 2 years across multiple study sites.

NCT ID: NCT04408326 Recruiting - Clinical trials for Acute Respiratory Distress Syndrome

Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome

ACES
Start date: June 1, 2020
Phase:
Study type: Observational

This study aims to find out whether the use of angiotensin II, which is a drug to raise blood pressure has been approved by European Medical Agency in August 2019, as an add-on medication to increase blood pressure in patients with COVID-19, acute severe lung injury, inflammation and severe shock, compared with standard medication. In addition, the investigators will collect the data of Anakinra, another drug which is frequently used in this condition to reduce inflammation. The investigators will collect clinical data and outcomes from critical care patients. The investigators will analyse for whom these drugs are most beneficial and explore whether there are any patients who don't benefit or have side effects.

NCT ID: NCT04407936 Completed - Clinical trials for Coronary Artery Disease

Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention

Start date: June 1, 2007
Phase:
Study type: Observational

As a single center, retrospective observation study in Guangdong Institute of Cardiovascular Diseases, this study included the main study population of patients who underwent coronary angiography and / or coronary intervention from January 2007 to Decemeber 2018. The hospitalization information was collected in the form of direct derivation of the case, and cardiac and renal adverse events were collected through outpatient recorder system. All-cause death information was obtained from the Public Security and matched to the electronic Clinical Management System of the Guangdong Provincial People's Hospital records.

NCT ID: NCT04407754 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Myo-Inositol for Infertility in PCOS

Start date: December 19, 2020
Phase: N/A
Study type: Interventional

This will be a prospective, double-blind randomized clinical trial of letrozole and placebo versus letrozole and inositols for up to 5 treatment cycles of ovulation induction or until pregnancy is achieved. All participants and members of the research team will be blinded to the treatment arms. Placebo and inositol supplement will be packaged to appear the same, tested, and packaged by a commercial supply company. The inositols will be a 40:1 blend of myo-inositol and D-chiro inositol.

NCT ID: NCT04405856 Recruiting - Clinical trials for Coronary Artery Disease

Outcome of Patients Treated With IABP

Start date: February 1, 2012
Phase:
Study type: Observational

Intra-Aortic Balloon Pumps (IABP) is a widely used and effective left ventricular adjuvant therapy. IABP is an inflatable device placed in the aorta that inflates with diastole and deflates with systole. The aim of this study is to investigate the outcome of patients treated With IABP, and to evaluate the short-term and long-term outcomes of patients with IABP.

NCT ID: NCT04405648 Completed - Clinical trials for Computer Vision Syndrome

Computer Vision Syndrome Prevalence Among University Students

Start date: May 28, 2020
Phase:
Study type: Observational

CVS-F3 questionnaire will be used as an instrument to survey CVS prevalence and severity among medical students

NCT ID: NCT04404816 Completed - Clinical trials for Respiratory Distress Syndrome

Effects of Non-invasive Ventilation With Helium-oxygen Mixture in Premature Infants With Respiratory Distress Syndrome

Start date: January 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The use of a mixture of helium with oxygen (heliox) as a breathing gas may be beneficial due to its unique physical properties, such as low density and high carbon dioxide (CO2) diffusion coefficient. In previous studies in neonates with respiratory failure, conventional ventilation with heliox was associated with improved oxygenation and selected respiratory parameters. The use of heliox may increase the effectiveness of intermittent nasal positive pressure ventilation (NIPPV), but knowledge about the effects of such therapy on newborns is limited.The use of non- invasive neurally adjusted ventilatory assist (NIV-NAVA) allows synchronization and assessment of electrical activity of the diaphragm (EaDI) during heliox administration in premature babies with respiratory failure.

NCT ID: NCT04403854 Not yet recruiting - Clinical trials for Chronic Fatigue Syndrome

Structural Problems in Brainstem and Cervical Spine Cord in ME/CFS

Start date: April 1, 2021
Phase:
Study type: Observational

A case control study on patients with ME/CFS and healthy controls on prevalence of cervical obstructions, Cerebro spinal fluid (CSF) pressure and laboratory findings.

NCT ID: NCT04402957 Completed - Acute Kidney Injury Clinical Trials

LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19)

Start date: October 14, 2020
Phase: Phase 2
Study type: Interventional

To evaluate the proportion of subjects alive and free of respiratory failure (e.g. need for non-invasive or invasive mechanical ventilation, high flow oxygen, or ECMO) and free of the need for continued renal replacement therapy (RRT) on Day 28. The need for continued RRT at Day 28 will be defined as either dialysis in the past 3 days (Day 26, 27, or 28) or an eGFR on Day 28 <10 mL/min/1.73 m2.