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NCT ID: NCT04602104 Recruiting - Clinical trials for Acute Respiratory Distress Syndrome

A Clinical Study of Mesenchymal Stem Cell Exosomes Nebulizer for the Treatment of ARDS

Start date: November 30, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate allogeneic human mesenchymal stem cell exosomes (hMSC-Exos) in the treatment of acute respiratory distress syndrome (ARDS)

NCT ID: NCT04601467 Recruiting - Clinical trials for Acute Coronary Syndrome

PASSIvation of Vulnerable Plaque With AZD5718 in AcuTe Coronary syndromE

PASSIVATE
Start date: July 12, 2021
Phase: Phase 2
Study type: Interventional

This is a multi-center study conducted at 13 sites in 3 countries (Singapore, New Zealand, and the Australia). Approximately 260 patients with an acute myocardial infarction (AMI) will be randomized in a ratio of 1:1 ratio to receive AZD5718 125 mg or placebo for 12 months.

NCT ID: NCT04601090 Completed - Covid19 Clinical Trials

Survival Rates and Longterm Outcomes After COVID-19

Start date: September 16, 2020
Phase:
Study type: Observational [Patient Registry]

The study 'Survival rates and long-term outcomes for patients with COVID-19 admitted to Norwegian ICUs' is a national observational study, including patients admitted to a Norwegian ICU between March 2020 and March 2021. The study will describe survival rates, clinical characteristics and health challenges experienced by survivors the first year after ICU admission caused by COVID-19 disease.

NCT ID: NCT04600986 Completed - Clinical trials for Polycystic Ovary Syndrome

Repeated Doses of GnRH Agonist as Oocyte Triggering in Antagonist Protocol for Patients With Polycystic Ovary Syndrome

Start date: May 30, 2020
Phase: N/A
Study type: Interventional

This is a prospective, randomized, proof-of-concept study, designed to compare the IVF results in patients diagnosed with polycystic ovarian syndrome (PCOS) defined as per the ESHRE/ASRM Rotterdam criteria (2003) undergoing in-vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI) in antagonist protocol. Patients were randomized into two groups. Group A: single dose of GnRHa 0.2 mg, 35 h prior to oocyte retrieval, and Group B: 0.2 mg GnRHa 35 h prior to oocyte retrieval + a repeat dose of 0.1 mg 12 h following the 1st dose. 12 h post-trigger, luteinizing hormone (LH), progesterone (P4) values will be estimated.

NCT ID: NCT04600427 Withdrawn - Ogilvie Syndrome Clinical Trials

Epidural for Ogilvie's Syndrome

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Epidural anesthesia may represent a safe and effective pharmacological tool in the management of Ogilvie's Syndrome. This pilot study aims to demonstrate feasibility, safety, and efficacy of epidural anesthesia to set the stage for adequately powered future randomized controlled trials (RCTs) in order to assess the efficacy of epidural anesthetic as a pharmacological treatment strategy for Ogilvie's Syndrome. Ultimately, this research may prompt further investigation and establish standardized criteria for managing Ogilvie's Syndrome patients with epidural anesthesia.

NCT ID: NCT04600037 Completed - Clinical trials for Myofascial Pain Syndrome

Pregabalin Treatment for Trigger Points

Start date: April 26, 2014
Phase: N/A
Study type: Interventional

Myofascial pain syndrome (MPS) is a common problem in the general population. MPS should not be a local/peripheral painful syndrome and considered to be a syndrome of central sensitivity. We aimed to investigate the effect of pregabalin in patients with MPS in this study

NCT ID: NCT04600024 Completed - Anthropometry Clinical Trials

Pelvic and Hip Morphometry in Piriformis Syndrome

Start date: April 20, 2018
Phase:
Study type: Observational

In this case-control study, 23 patients diagnosed as PS by diagnostic injection with ultrasound guidance were selected as the study group. 22 patients who were excluded from the diagnosis of PS and had anteroposterior (AP) direct radiographic imaging were evaluated as the control group. On the AP Pelvic graph, the femoral neck-shaft angle, the distances between predetermined bony landmarks were measured blindly without knowing the diagnosis, and the findings were compared statistically. This study aims to evaluate whether the anatomical structure of the pelvis predisposes to the etiopathogenesis of the piriformis syndrome.

NCT ID: NCT04599400 Completed - Clinical trials for Myofascial Pain Syndrome, Diffuse

Online Information on Myofascial Pain Syndrome

Start date: April 1, 2020
Phase:
Study type: Observational

The investigators aim in this study is to evaluate myofascial pain syndrome (MPS) related websites in terms of the quality and the readability of the information. Also, to identify the typologies of websites that provide high-quality information about MPS.

NCT ID: NCT04599296 Completed - Clinical trials for Femoroacetabular Impingement Syndrome

Postoperative Hip Bracing After Hip Arthroscopy

Start date: November 1, 2020
Phase: N/A
Study type: Interventional

Hip arthroscopy for treatment of femoroacetabular impingement syndrome (FAIS) involves reshaping of the osseous sources of impingement ("osteoplasty") and treatment of impingement-associated labral tears with labral repair. Postoperative hip braces are advocated to decrease postoperative pain by offloading hip musculature. However there are no studies looking at efficacy of hip braces after hip arthroscopy, and on average 50% of high-volume hip arthroscopists use bracing. The objective of this study is to use a randomized controlled trial to test the cited benefits of postoperative hip bracing on short term patient reported pain scores, validated hip-specific pain scores, and physical exam findings of hip flexor tendonitis.

NCT ID: NCT04599127 Completed - Clinical trials for Shoulder Impingement Syndrome

The Effect of Mobilization With Movement in Individuals With Shoulder Impingement Syndrome

SIS
Start date: August 12, 2019
Phase: N/A
Study type: Interventional

This study conducted to see the effect of adding mobilization with movement to conventional physical therapy to the subject with shoulder impingement syndrome. The shoulder impingement syndrome is often described as anterior lateral shoulder pain that provoked during shoulder elevation. The pain occurs during shoulder elevation and causes limited range of motion. Moreover, the patients with shoulder impingement syndrome commonly had a forward head posture and slouching shoulder. There is a theory that illustrates the mechanical factors lead to the injury of the bursa or rotator cuff tendons below the subacromial space which is highly related to the posture and scapular movement. Various treatments for shoulder impingement syndrome including medical treatments such as anti-inflammatory drugs, subacromial decompression, and acromion resection surgery. Conventional physical therapy treatments for shoulder impingement syndrome included modalities, exercises and manual therapy. Exercise has been showed to give a significant effect to decrease the pain intensity, increasing the range of motion and shoulder function. There is evidence that supports the use of manual therapy on shoulder impingement, the recent technique introduced by Brian Mulligan is mobilization with movement. Mobilization with movement is a manual therapy technique that uses the active movement while the physical therapist applies an accessory force to align the positional fault of the joint. A previous study investigated the effect of mobilization with movement that uses the mobilization with movement in shoulder impingement syndrome showed different outcomes in the measurement of pain intensity and shoulder range of motion. As the posture may be related to shoulder impingement syndrome, this research will measure the cervical posture, shoulder posture, and muscle strength. Therefore, the purposes of this study will be to compare the effects of conventional physical therapy treatments and the conventional therapy treatments plus the mobilization with movement on pain intensity, shoulder range of motion, cervical and shoulder posture, shoulder muscle strength and shoulder function. The study hypothesis was that mobilization with movement is more effective in improving the investigated outcomes in individuals with shoulder impingement syndrome than the conventional physical therapy.