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Syndrome clinical trials

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NCT ID: NCT05626634 Active, not recruiting - Dravet Syndrome Clinical Trials

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Start date: November 8, 2022
Phase: Phase 2
Study type: Interventional

The objective of this study is to assess the long-term safety, tolerability, and efficacy of adjunctive therapy of LP352 in subjects with developmental and epileptic encephalopathies who completed participation in Study LP352-201.

NCT ID: NCT05625568 Not yet recruiting - Rett Syndrome Clinical Trials

Study of VYNT-0126 in the Treatment of Rett Syndrome in Adult Patients

Start date: March 2023
Phase: Phase 2
Study type: Interventional

This is an exploratory, Phase 2, multicenter, double-blind, parallel-group, placebo-controlled study to assess the safety, tolerability, and efficacy of oral treatment with VYNT-0126 in female subjects 18-45 years of age with Rett syndrome.

NCT ID: NCT05624866 Recruiting - Clinical trials for Carpal Tunnel Syndrome

Dexmedetomidine Versus Triamcinolone Treatment in Carpal Tunnel Syndrome

Start date: October 10, 2022
Phase: N/A
Study type: Interventional

Carpal tunnel syndrome (CTS) is a common mononeuropathy due to entrapment of the median nerve in the carpal tunnel. a lot of modalities are available for treatment of mild to moderate CTS.

NCT ID: NCT05623033 Recruiting - Infections Clinical Trials

The Predictive Value of Dynamic Changes of CD4+T Lymphocytes in Primary Nephrotic Syndrome With Infection

Start date: November 16, 2022
Phase:
Study type: Observational

The goal of this observational study is to test whether the dynamic changes of CD4+T lymphocytes can predict infections in patients with primary nephrotic syndrome . The main questions it aims to answer are: - whether the dynamic changes of CD4+T lymphocytes can predict infections in patients with primary nephrotic syndrome - effect of different immunosuppressive therapy on the number and function of T lymphocyte subsets in patients with primary nephrotic syndrome Participants will be divided into infection group and non-infection group according to whether they are infected

NCT ID: NCT05622292 Recruiting - Clinical trials for Acute Coronary Syndrome

The Effectivity of the Mobile App "HARKIT I-Care" in Secondary Prevention in Post-ACS Patients

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

HARKIT I-Care is a mobile application developed by the National Cardiovascular Center Harapan Kita (NCCHK) to leverage patients in achieving their targets for the secondary prevention of cardiovascular diseases. The application contains various features, including exercise tracking and reminder, medication reminder, and updated educational content on cardiovascular health. Additionally, patients can log and record their blood pressure, heart rate, smoking behavior, Quality of Life, and laboratory parameters such as blood sugar and cholesterol. Our research aims to investigate whether implementing this app in post-acute coronary syndrome patients could improve their survival rate, hospitalization rate, medication adherence, and Quality of Life, along with improving their laboratory parameters to be within desirable targets.

NCT ID: NCT05618470 Recruiting - Dry Eye Syndromes Clinical Trials

Wumeiwan Jiawei Fang Use in Patients With Blepharospasm

Start date: January 12, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

To evaluate the efficacy and safety of Jing Fang Wu Mei Wan Jiawei Fang in the treatment of idiopathic blepharospasm using a clinical randomized controlled trial method.

NCT ID: NCT05618106 Completed - Clinical trials for Irritable Bowel Syndrome

Low FODMAP Diet in Patients With IBS

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

The aim was aimed to investigate if all carbohydrate groups eliminated in the Low FODMAP diet are equally important in relieving gastrointestinal symptoms in IBS. in a randomized cross-over design to three different carbohydrate-modified diets: A) Low Polyol diet, B) Low FOS+GOS diet, and C) Low FODMAP diet for three months without wash-out-periods. Gastrointestinal symptoms, Quality of life was measured at baseline and after each intervention diet.

NCT ID: NCT05617911 Terminated - Clinical trials for Patellofemoral Pain Syndrome

Clinical Comparison of Patellofemoral Pain Syndrome Outcomes After Blood Flow Restriction Therapy

Start date: November 15, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if Blood Flow Restriction therapy improves patient related outcomes in those diagnosed with Patellofemoral Pain Syndrome compared to those in the sham comparator control group.

NCT ID: NCT05617625 Suspended - Clinical trials for Myelodysplastic Syndromes

CD34+ Enriched Transplants to Treat Myelodysplastic Syndrome

Start date: June 2024
Phase: Phase 2
Study type: Interventional

This study will evaluate whether processing blood stem cell transplants using an investigational device (the CliniMACS system) results in fewer complications for patients who undergo transplant to treat a blood malignancy (cancer) or blood disorder. The CliniMACS system will be used to remove immune T-cells from the transplant donor's blood. Immune T-cells contribute to graft versus host disease (GVHD) - a serious complication that can happen after transplant. GVHD occurs when a patient's immune system attacks the donor's cells. The study aims to reduce the number of the donor immune T-cells thereby preventing or reducing the severity of GVHD.

NCT ID: NCT05617118 Recruiting - Chronic Pain Clinical Trials

BTA vs Baclofen for Pelvic Myofascial Pain Syndrome

BvsB
Start date: December 1, 2022
Phase:
Study type: Observational

The aim of the study is to test the hypothesis that oral taking of baclofen in therapeutic dosage for 60 days is equally effective as injection of botulinum toxin type "A" in the area of trigger points of the pelvic muscles.