Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment

Stroke Clinical Trial

— PANGEA  

Official title:

Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02381977
• Other study ID #: PANGEA
• Status: Completed
• Phase: N/A
• First received: February 16, 2015
• Last updated: March 2, 2015
• Start date: November 2011
• Est. completion date: September 2014

Study information

• Verified date: March 2015
• Source: University of Pittsburgh
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

PANGEA is an international prospective point prevalence study to describe the epidemiology, interventions, and outcomes in children with acute critical brain disease.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 922
• Est. completion date: September 2014
• Est. primary completion date: October 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A to 17 Years

Eligibility

Inclusion Criteria:

1. Children aged 7 days to 17 years inclusively and admitted to an ICU (ICU can be classified as general, cardiac, trauma, etc).

2. Children with acute or acute on chronic neurologic disease that occurred just prior to hospital admission or occurred during the hospital admission.

3. Acute neurologic disease is secondary to TBI, stroke, brain mass, hydrocephalus, cardiac arrest, status epilepticus, CNS infection/inflammation, or spinal cord injury.

Exclusion Criteria:

1. Children with acute perinatal neurologic disease.

2. Children with isolated chronic brain injury and no acute neurologic disease.

Study Design

Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Brain Mass
• Cardiac Arrest
• Heart Arrest
• Hydrocephalus
• Nervous System Diseases
• Spinal Cord Disease
• Spinal Cord Diseases
• Status Epilepticus
• Stroke
• Traumatic Brain Injury

Intervention

Other:
• No intervention

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
University of Pittsburgh	Laerdal Medical

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence of acute brain insult		4 days over a 1 year period	No
Secondary	Mortality		Hospital discharge or 3 months	No