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Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease

Stroke Clinical Trial

Official title:
Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease

Clinical Trial Summary

The investigators hypothesize that inflammation in carotid plaque is predictive of the extent of ischemic lesion burden on the brain and will add to risk stratification for individuals with carotid disease.

Clinical Trial Description

Objectives:

1. To investigate the relationship of carotid inflammation, as measured by FDG positron emission tomography (PET) to standardized uptake value in atherosclerotic plaque, with the number of covert brain infarcts.

2. To investigate the relationship of FDG PET standardized uptake value with the relative volume of white matter hyperintensity.

3. To correlate vascular inflammation in the entire aorta and aortoiliac vessels to carotid inflammation and cerebral infarcts and white matter disease. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01236508
Study type Interventional
Source Ottawa Heart Institute Research Corporation
Contact
Status Terminated
Phase Phase 4
Start date November 2010
Completion date October 27, 2016
View Details
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