Stroke, Ischemic Clinical Trial
Official title:
The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Observational)
The study is aimed at the investigation of the association of biomarkers of circadian rhythms with sleep characteristics and stroke outcome in acute stroke patients. It is designed as an observational cohort study with the retrospective and prospective longitudinal arms.
In the retrospective arm of the study, the routinely collected data of patients admitted to the stroke unit with acute ischemic stroke (from 2018 till 2022) will be evaluated. In the prospective longitudinal arm, about 200-250 patients admitted to the Stroke Unit of one participating center will undergo examination including the assessment of medical records, stroke characteristics, sleep characteristics and blood sampling for the evaluation of genetic biomarkers of circadian rhythms within the first 2-3 days after admission.The assessment of stroke severity and functional deficit will be repeated at 10-14 days after stroke. The following associations will be assessed: - the association of genetic biomarkers of circadian rhythms with stroke outcome (the difference in neurological and functional deficit from admission to 14th day after stroke), with stroke characteristics (stroke subtype and neuroimaging stroke parameters) and with sleep characteristics. - the association of sleep characteristics with stroke outcome (the difference in neurological and functional deficit from admission to 14th day after stroke) and with stroke characteristics (stroke subtype and neuroimaging stroke parameters). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03993236 -
Study on Rosuvastatin+Ezetimibe and Rosuvastatin for LDL-C Goal in Patients With Recent Ischemic Stroke
|
Phase 4 | |
| Completed |
NCT04069767 -
Innovative Physiotherapy in Stroke Rehabilitation
|
N/A | |
| Recruiting |
NCT06342206 -
The Assessment of Acute /Chronic Phase in Patients With Ischemic Cerebral Stroke Using TCM Diagnostic Tools
|
||
| Recruiting |
NCT03605381 -
MORbidity PRevalence Estimate In StrokE
|
||
| Enrolling by invitation |
NCT04956211 -
Periodontal Treatment and Ischemic Stroke
|
N/A | |
| Active, not recruiting |
NCT05098236 -
Effect of Visual Retraining on Visual Loss Following Visual Cortical Damage
|
N/A | |
| Completed |
NCT03942588 -
High-intensity Interval Training After Stroke
|
N/A | |
| Recruiting |
NCT04949334 -
Effects of Respiratory Muscle Training in Patients With Acute Ischemic Stroke
|
N/A | |
| Terminated |
NCT04095767 -
Assessing Safety and Performance of the ANA Catheter System, Combined With a Stent Retriever in Acute Ischemic Stroke
|
N/A | |
| Not yet recruiting |
NCT06352086 -
Understanding Visual Processing After Occipital Stroke
|
||
| Withdrawn |
NCT04991038 -
Clinical Investigation to Compare Safety and Efficacy of DAISE and Stent Retrievers for Thrombectomy In Acute Ischemic Stroke Patients
|
N/A | |
| Completed |
NCT01937182 -
The Efficacy of Citalopram Treatment in Acute Stroke
|
Phase 2 | |
| Completed |
NCT03649295 -
Combined Conventional Speech Therapy and Functional Electrical Stimulation in Dysphagia Following Stroke
|
N/A | |
| Recruiting |
NCT05303649 -
Effects of Neuronavigated Theta Burst Stimulation in Therapy of Post-stroke Aphasia
|
N/A | |
| Completed |
NCT04233515 -
Use of Oral Anticoagulants and Symptoms in Patients With Atrial Fibrillation in Örebro County
|
||
| Completed |
NCT05102877 -
Sensory Versus Motor Level Neuromuscular Electrical Stimulation
|
N/A | |
| Completed |
NCT04089917 -
A Study of the Use of the Q Aspiration Catheter to Remove Clot in Stroke Patients
|
||
| Completed |
NCT05221112 -
Effects of PNF Patterns Training on Trunk Balance, and Gait in Chronic Stroke Patients
|
N/A | |
| Not yet recruiting |
NCT05035953 -
Thrombolysis Combined With Edaravone Dexborneol on Hemorrhagic Transformation for Acute Ischemic Stroke
|
Phase 2 | |
| Completed |
NCT06326801 -
Resistive Diaphragmatic Breathing Exercise With Pursed Lips Breathing Exercise in Sub-acute Stroke Patients
|
N/A |