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Stress clinical trials

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NCT ID: NCT03869749 Terminated - Anxiety Clinical Trials

The Moving 2 Mindful (M2M) Study: Mindfulness Group + Ecological Momentary Intervention

M2M
Start date: February 17, 2021
Phase: N/A
Study type: Interventional

This study will evaluate the feasibility and acceptability of Learning to BREATHE (a mindfulness intervention for adolescents) plus an ecological momentary intervention (Learning to Breathe Plus), and will examine the extent to which mindfulness reduces dysregulated stress physiology, perceived stress, and anxiety in adolescents from high conflict homes.

NCT ID: NCT03587896 Terminated - Stress Clinical Trials

Implementation of Self Help Plus in Adult Syrian Refugees in Turkey (RE-DEFINE)

RE-DEFINE
Start date: September 1, 2018
Phase: N/A
Study type: Interventional

This study evaluates the effectiveness and cost-effectiveness of the SH+ in Arabic speaking people including Syrians under the temporary protection of Republic of Turkey and other Arabic speaking immigrants and asylum seekers with psychological distress in Turkey. Half of participants will receive Self Help Plus (SH+), while the other half will receive enhanced treatment as usual.

NCT ID: NCT03413969 Terminated - Stress Clinical Trials

Building Physician Resiliency Through CREATION Health: A Research Study

Start date: March 20, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a standardized application of a physician-oriented CREATION Health curriculum is associated with reductions in burnout and perceived stress and improvements in well-being and empathy

NCT ID: NCT02813447 Terminated - Depression Clinical Trials

Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD)

SAD-COPD
Start date: August 2016
Phase: N/A
Study type: Interventional

Objective: Determine whether treatment of perceived stress, anxiety, and depression with anti-depressant therapy improves dyspnea scores, 6-minute walk (6MW) distance and quality of life (QoL) in patients with Chronic Obstructive Pulmonary Disease (COPD) and ILD (Interstitial Lung Disease) undergoing pulmonary rehab. The study is a prospective, randomized, double-blinded, placebo-controlled study to assess the effect of an SSRI on 6MW, dyspnea scores, and QoL in COPD and ILD patients undergoing pulmonary rehab. Thirty subjects that carry an ICD-9 code diagnosis of COPD and/or ILD and CES-D (Center for Epidemiologic Studies Depression) score of > 16 will be recruited from Duke Pulmonary Rehab. Multivariable regression models will be constructed to evaluate the relationship between perceived stress, anxiety, and depression with adjustments by race, gender, age, BMI and GOLD score. A multivariable regression model will be constructed to assess whether treatment of perceived stress, depression, and anxiety with antidepressant therapy (sertraline) is an effect modifier on 6MW distance and dyspnea scores in patients with COPD or ILD who are enrolled in pulmonary rehab. Descriptive statistics will be used to examine the socio-demographic characteristic data. Student t-tests will be performed to assess group differences in continuous data. Categorical variables will be examined using the Pearson's Chi-Squared test.

NCT ID: NCT01763736 Terminated - Anxiety Clinical Trials

Medical Use of Song In Critical Care (MUSIC)

MUSIC
Start date: December 2012
Phase: N/A
Study type: Interventional

The objective of this research study is to assess the effects of music on patients' experience in the Intensive Care Unit (ICU). The hypothesis of this study is that patients who receive music therapy will report a reduction in negative recollections and experiences while on mechanical ventilation and will require fewer pharmacologic agents to maintain their sedation.

NCT ID: NCT01736280 Terminated - Obesity Clinical Trials

Evaluating and Treating Potential Research Participants With Digestive Disorders

Start date: September 17, 2012
Phase: N/A
Study type: Interventional

Background: - Some research studies focus on digestive disorders, such as nutritional, gastrointestinal, and liver disorders. Researchers want to examine and treat people with digestive disorders in order to learn more about these disorders. They also want to study how digestive disorders run in some families. To do so, they will provide standard care to people with digestive disorders. They will also look at relatives of people with digestive disorders, such as parents, children, and siblings. Objectives: - To examine and treat people with digestive disorders. - To evaluate people with digestive disorders for research studies. Eligibility: - Individuals of any age who have digestive disorders. - Individuals at least 2 years of age who are first-degree relatives of the people with digestive disorders. Design: - Participants will have at least one outpatient visit to the National Institutes of Health. The visit will last about 2 hours. - All participants will be screened with a physical exam and medical history. They will also provide different samples for study. Samples may include blood, urine, and stool samples. Saliva and hair samples may also be taken. Skin biopsies and rectal swabs may be collected from adult participants. - Participants with digestive disorders may be able to receive treatment through this study.

NCT ID: NCT00859066 Terminated - Anxiety Clinical Trials

Evaluation of Radiology Resident Anxiety When Beginning Emergency Room (ER) Call

Start date: January 2009
Phase: N/A
Study type: Observational

The purpose of this study is to quantify levels of resident anxiety under the current system (take call alone) and compare results to a modified system.

NCT ID: NCT00824941 Terminated - Obesity Clinical Trials

Brain-Gut Interactions in Overweight and Normal Weight Patients With Chronic Abdominal Pain

Start date: February 6, 2009
Phase:
Study type: Observational

About 15 to 20 percent of individuals living in the United States have chronic abdominal pain, often of unknown origin, which is often difficult to diagnose and treat. One possible cause of chronic abdominal pain is an inflammation of the intestines, but it is not known whether the two are related. Furthermore, although overweight people tend to be more likely to have increased inflammation, it is not known whether there is a connection between increased body weight and chronic abdominal pain. This study will examine the relationship between symptoms of chronic abdominal pain and intestinal inflammation by comparing the medical test results of normal weight and overweight patients who have a history of chronic abdominal pain. This study will include 224 subjects, who must be men and women between the ages of 13 and 45. Half the subjects will be healthy participants, and half will have had chronic abdominal pain of unknown origin for longer than 6 months. Female participants must take a urine pregnancy test before starting the study, and will not be allowed to participate if the test is positive. During the study, patients will visit the NIH Clinical Center on two occasions for testing. On the first visit, patients will provide a medical history, including information about current medications or natural remedies and tobacco and alcohol use, and will also fill out questionnaires to provide information about symptoms, current levels of gastrointestinal pain, and general quality of life. The study researchers will conduct a physical examination, measure patients height and weight, and draw blood for testing. Patients will be asked to not eat or drink anything for 8 hours before the second visit, and will be asked to bring a bathing suit and a swim cap to the Clinical Center. On the day of the visit, patients will fill out questionnaires to provide information about symptoms, current levels of gastrointestinal pain, and general quality of life. Patients will also provide a blood sample for testing. Researchers will measure patients blood pressure and heart rate, height, weight, waist/hip circumference, and intra-abdominal measurement. Patients will also be asked to put on the bathing suit and swim cap to have their body fat measured using a machine called the BOD POD. To test the gastrointestinal system, patients will then be asked to drink a sugar-based test solution, and researchers will collect all voided urine for the next 5 to 6 hours. (Patients may drink water during this time.) On either Day 1 or Day 2 of the study, patients will sip, swish and spit an additional sweet taste solution. Patients will sip, swish, and spit different concentrations of this sweet taste solution, for a total of 25 tastings of this solution. Subjects will then complete questionnaires about their sweetness preferences related to these 25 tastings.

NCT ID: NCT00624520 Terminated - Stress Clinical Trials

Mental Stress Reduction in Defibrillator Patients

Start date: September 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the effectiveness of a 10 week program of Stress Management versus control Patient Education sessions on cardiac responses to mental stress in veterans with Implantable Cardioverter-Defibrillators