Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Social Functioning Scale |
The Social Functioning Scale (SFS) is an interview-based measure administered to an informant and assesses domains of social engagement, interpersonal communication, independence, recreation, prosocial behavior, and vocational activities. Items have various scales and ways to interpret them since this is a longer, interview-based measure. |
Change between baseline assessment and 18-month assessment |
|
Secondary |
World Health Organization Quality of Life Scale Brief Version (WHOQOL-BREF) |
Quality of Life will be assessed using the World Health Organization Quality of Life Scale Brief Version (WHOQOL-BREF), which contains 26 items assessing 4 domains: physical health, psychological, social relationships, and environment. The WHOQOL-BREF is reliable and valid in schizophrenia. |
Change between baseline assessment and 18-month assessment |
|
Secondary |
Questionnaire About the Process of Recovery |
Personal Recovery will be assessed using the Questionnaire About the Process of Recovery, a 15-item self-report measure collaboratively developed with service-users experiencing psychosis. |
Change between baseline assessment and 18-month assessment |
|
Secondary |
Positive and Negative Syndrome Scale (PANSS) |
Psychiatric Symptoms will be assessed with the Positive and Negative Syndrome Scale (PANSS), the gold standard symptom interview for schizophrenia. The PANSS assesses positive, negative, and general symptoms, and a 15-point change on the PANSS is associated with clinically meaningful change. |
Change between baseline assessment and 18-month assessment |
|
Secondary |
Psychotic Symptom Rating Scale (PSYRATS) |
The Psychotic Symptom Rating Scale (PSYRATS) is an interview assessing dimensions of hallucination and delusion severity that members of our team validated. |
Change between baseline assessment and 18-month assessment |
|
Secondary |
MATRICS Consensus Cognitive Battery (MCCB) |
Neurocognition will be assessed using the MATRICS Consensus Cognitive Battery (MCCB), the gold standard assessment of cognitive functions for schizophrenia. The MCCB assesses domains of processing speed, sustained attention, verbal learning, visual learning, working memory, and reasoning / problem solving. Extensive normative data will be used to generate a global neurocognitive composite score. |
Change between baseline assessment and 18-month assessment |
|
Secondary |
Beliefs About Paranoia Scale (BAPS) |
Assesses cognitive content. Each item was scored on a 4-point scale to measure conviction (1 = not at all, 2 = somewhat, 3 = moderately so, 4 = very much). |
Change between baseline assessment and 18-month assessment |
|
Secondary |
Interpretations of Voices Inventory (IVI) |
Assesses cognitive content. |
Change between baseline assessment and 18-month assessment |
|
Secondary |
Brief Core Schema Scale (BCSS) |
Assesses cognitive content. Participants indicate whether they hold each of the beliefs using No or Yes, and if they do hold the belief, they indicate how strongly they hold it by circling the numbers 1 to 4 (believe it slightly, believe it moderately, believe it very much, believe it totally). |
Change between baseline assessment and 18-month assessment |
|
Secondary |
Defeatist Beliefs Scale (from Dysfunctional Attitudes Scale, DAS) |
Assesses cognitive content. The rating format for the 80 Dysfunctional Attitudes Scale items is a 7-point Likert scale ranging from totally agree to totally disagree. Possible responses are scored from 1 to 7, with the direction depending on whether agreement or disagreement with a particular belief is judged to be a maladaptive response, and with higher scores indicating more distorted thinking. |
Change between baseline assessment and 18-month assessment |
|
Secondary |
Questionnaire on Healthcare Consumption and Productivity Losses for Patients with a Psychiatric Disorder (TiC-P) |
The TiC-P is a self-report measure that has been validated against objective health data. |
Change between baseline assessment and 18-month assessment |
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