Schizophrenia Clinical Trial
Official title:
Integration of Illness Management and Recovery Within ACT
Integrating Illness Management and Recovery (IMR) into Assertive Community Treatment (ACT) has great promise for improving the symptomatic, functional, and recovery outcomes for people with Serious Mental Illness (SMI), especially those individuals who have the greatest needs. In addition to these positive consumer outcomes, system benefits may also accrue due to more rapid graduation of consumers from ACT (with IMR) programs to less intensive levels of care. However, before these benefits can be realized, research and development are needed to design and pilot test a treatment manual that is feasible and acceptable to consumers and staff for integrating IMR and ACT.
Despite significant advances in pharmacological treatments, many individuals with severe
mental illnesses (SMI) such as schizophrenia and bipolar disorder continue to experience
significant impairments in crucial life areas such as employment, housing, social
functioning, and daily living skills. In addition, many of these individuals have
significant levels of psychotic, mood, or negative symptoms, and are prone to frequent
relapses and re-hospitalizations. Psychosocial treatments are needed to improve illness
management and functioning beyond the limited effects of medication. However, relatively few
psychosocial evidence-based practices (EBPs) exist for people with SMI and only a small
percentage of people who could benefit from these treatments actually receive them. At the
federal level, the implementation and dissemination of EBPs for people with SMI is a major
policy priority and research objective.
Assertive Community Treatment (ACT) Overview. ACT is one of five psychosocial treatments for
people with SMI designated as an EBP by SAMHSA. Since its inception, ACT has grown from a
single, experimental research treatment program to an essential element within the service
continuum of most public mental health systems for people with SMI. ACT programs typically
serve consumers with the most severe symptoms who have the greatest disability and support
needs (e.g., high rates of homelessness and hospitalizations), and who are most difficult to
engage and retain in standard outpatient programs.
Research on ACT is extensive, with more than 25 RCTs. Literature reviews consistently
conclude that ACT is more effective than standard community mental health services with
demonstrated effectiveness in reducing psychiatric hospitalizations, and improving community
tenure, retention in treatment, and high consumer and family satisfaction with services.
However, ACT is less effective at improving symptom management, social functioning, and
other functional outcomes, and needs to be adapted to better facilitate recovery. ACT is
cost-effective compared to standard case management and has been widely disseminated with
more than 300 ACT programs in at least 41 states.
Illness Management and Recovery (IMR) Overview. The Illness Management and Recovery (IMR)
program is well-suited for enhancing outcomes in those areas less effectively addressed by
ACT: symptom management and community functioning. IMR is also one of five psychosocial EBPs
identified by SAMHSA for adults with SMI. IMR programs have been widely implemented across
the U.S. and other countries, and researchers have conducted a number of open clinical
trials and quasi-experimental studies. Recently, three RCTs were conducted, supporting the
effectiveness of group-based IMR implemented in outpatient mental health clinics and
supported housing. These studies show significant positive outcomes with IMR, including
symptom reduction, improved functioning, increased knowledge about mental illness, and
progress toward personal recovery goals.
Although these positive results support the effectiveness of IMR, several gaps and
limitations are apparent in this growing area of practice and research. First, although IMR
has been implemented clinically with very symptomatic consumers, such as inpatient and
residential settings, controlled research on IMR has focused on outpatient settings,
involving consumers who tend to be less symptomatic and higher functioning than those
typically served on ACT teams. Second, providing IMR in outpatient clinics restricts the
ability of clinicians to teach consumers skills in more natural community venues, which
could improve the acquisition of new skills and related functional gains. Third, research on
IMR has been mainly limited to the group modality, and hence, little is known about the
effects of IMR provided in both individual and group formats.
Integrating IMR with ACT. Several characteristics of ACT suggest it will be an excellent
platform for integrating and implementing the IMR program. By design, ACT programs serve
people with the greatest needs who tend to drop out of standard outpatient programs; thus,
integrating IMR into ACT has the potential to improve illness self-management in those
consumers who need it most. The individualized and assertive outreach nature of ACT services
will also allow IMR to be delivered in both individual and group modalities, and the in vivo
practice of ACT will empower consumers to learn and practice IMR skills in their natural
settings. Finally, the ACT principle of working with families and natural supports will
facilitate the involvement of those supports in helping consumers to better manage their SMI
and to achieve their recovery goals.
IMR also serves as an important potential service partner for ACT. ACT has been criticized
by some as not being recovery-oriented. The integration of IMR may further enhance the
growing recovery philosophy of ACT teams by providing a specific approach to promoting
illness self-management and recovery that can be integrated into routine services. IMR can
also improve the limited effectiveness of ACT teams at reducing symptoms and improving
social and independent functioning. We also speculate (and plan to test in the subsequent,
larger R01 research program) that providing IMR will accelerate the graduation of consumers
from ACT, thereby increasing the number of slots available for new consumers in need of this
scarce resource, further enhancing its cost-effectiveness. Thus, the integration of ACT and
IMR has the potential to significantly benefit consumers with SMI, and increase the
efficiency of the ACT model.
Despite these potential benefits, there are substantial challenges to integrating IMR into
ACT teams. IMR has been developed and used primarily in traditional treatment settings, not
in mobile community treatment approaches (e.g. ACT). In practice, many ACT clinicians find
that their time is devoted to responding to daily crises and acute case management needs;
ACT staff members often have difficulty making time and learning how to implement more
learning-based and recovery-oriented interventions. Most critically, there are no
standardized guidelines for implementing IMR within ACT, making the integration of the two
EBPs even more challenging.
A few ACT teams, however, have foreseen the promise of integrating IMR into ACT. Using a
nonequivalent group design, Garfinkle and Storch found that ACT consumers in IMR treatment
showed a number of positive outcomes compared to ACT consumers without IMR services over 11
months, including lower hospitalization rates, improved retention of housing and competitive
employment, and more work toward personal recovery goals. Salyers and colleagues conducted a
small single group, pre-post pilot study to evaluate the feasibility of using peer
specialists trained in IMR on ACT teams, and found that consumers who received IMR improved
significantly on a measure of recovery, with a trend toward increased knowledge of mental
illness, and consumer and staff satisfaction with IMR services. In a second study, Salyers
and colleagues randomly assigned two of four ACT teams to IMR training and services (using
only peer and mental health specialist staff for IMR service delivery). They reported that
over the two-year period, ACT+IMR teams achieved moderate fidelity to IMR, but that rates of
penetration were low, with only 25% of consumers having any exposure to IMR. However,
secondary analyses found that ACT consumers who received IMR showed significant reductions
in hospitalizations and incarcerations, and improvements in illness self-management.
The lack of well developed guidelines for implementing IMR undoubtedly limited the
effectiveness of the program in the Salyers' project. Fortunately, lessons learned from this
study, as well as the SAMHSA EBP study on IMR and the present project team's practice and
research experience with both ACT and IMR, suggest that with a number of adaptations IMR can
be successfully integrated into ACT services. We plan to develop and implement the following
promising strategies for integrating these two EBPs in this project: (1) develop an adapted
manual, training resources, and fidelity scale specific to implementing IMR within ACT, (2)
provide intensive initial and follow-up booster clinician training, (3) provide regularly
scheduled clinical supervision of IMR within the ACT team, in addition to regularly
scheduled outside consultation by IMR+ACT experts during project startup, (4) create an
organizational culture that supports and champions the integration of IMR within ACT, (5)
cross-train all ACT staff to support the consumer's participation in IMR, and (6) create
several specific, strategic adaptations to ACT team operations and protocol to facilitate
the practice of IMR within daily ACT service activities. We expect these implementation
strategies to result in an integrated IMR+ACT program that yields positive outcomes both to
consumers and mental health service delivery systems.
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