Schizophrenia Clinical Trial
— CBT-EOfficial title:
Comparison of Emotion-focused Cognitive Behavior Therapy for Patients With Schizophrenia With Standard Treatment: Effects on Psychological Parameters and Rehospitalisation
Verified date | March 2020 |
Source | Philipps University Marburg Medical Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The present study is a pilot single-blind randomized controlled therapy study. Its aim is to assess the efficacy of an emotion-focussed form of Cognitive behavior Therapy that focusses on emotional processes that are involved in the formation and maintenance of delusions such as emotional stability, emotion regulation and self-esteem.
Status | Completed |
Enrollment | 64 |
Est. completion date | December 31, 2017 |
Est. primary completion date | December 31, 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - Diagnosis of schizophrenia, schizoaffective disorder, delusional disorder or brief psychotic disorder - Positive and Negative Syndrome Scale score in item P1 (delusions) of at least two - fluent in German language - agree to participate - estimated general intelligence of at least 70 (assessed with the German Wortschatztest (MWT-B) - no present suicidality Exclusion Criteria: - acute suicidality - comorbid diagnosis of borderline personality disorder and/or substance use disorder in the last six month - intake of Benzodiazepines |
Country | Name | City | State |
---|---|---|---|
Germany | University of Hamburg, Faculty of Clinical Psychology and Psychotherapy | Hamburg | |
Germany | University of Marburg, Faculty of Clinical Psychology and Psychotherapy | Marburg | Hessen |
Lead Sponsor | Collaborator |
---|---|
Philipps University Marburg Medical Center | University of Hamburg |
Germany,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Change in Reactions to paranoid thoughts Scale (REPT) | Assessment of cognitive and emotional reactions on paranoid thoughts | Change between assessment pre-therapy and assessment after six month of therapy | |
Other | Change in Symptom Checklist 9 (SCL-9) | Assessment of severity of self-reported symptoms of different mental disorders (depression, anxiety, phobia, obsessive-compulsive symptoms, etc.) | Change between assessment pre-therapy and assessment after six month of therapy | |
Other | Change in Satisfaction With Life Scale (SWLS) | Assessment of life satisfaction | Change between assessment pre-therapy and assessment after six month of therapy | |
Other | Change in Pittsburg Sleep Quality Inventory (PSQI) | Assessment of objective sleep quality and sleep problems | Change between assessment pre-therapy and assessment after six month of therapy | |
Other | Change in number of social contacts (SozE) | Assessment of number of social contacts in the last week | Change between assessment pre-therapy and assessment after six month of therapy | |
Other | Change in Perseverative Thinking Questionnaire (PTQ) | Assessment of self-reported perseverative thinking and worrying | Change between assessment pre-therapy and assessment after six month of therapy | |
Other | Change in Scale of Emotion Regulation Competencies (SEK-27) | Assessment of self-reported habitual use of different emotion regulation strategies | Change between assessment pre-therapy and assessment after six month of therapy | |
Other | Change in Self-Compassion Scale (SCS) | Assessment of self-reported self-compassion | Change between assessment pre-therapy and assessment after six month of therapy | |
Other | Change in Brief Core Schema Scale (BCSS) | Assessment of positive and negative self-schemas and positive and negative schemas of other persons | Change between assessment pre-therapy and assessment after six month of therapy | |
Primary | Change in Psychotic Rating Scale (PSYRATS) delusions scale | Assessment of delusion frequency, delusion distress, conviction and loss of quality of life | Change between assessment pre-therapy and assessment after six month of therapy | |
Secondary | Change in Positive and Negative Syndrome Scale (PANSS) | Assessment of positive, negative and general symptoms of schizophrenia | Change between assessment pre-therapy and assessment after six month of therapy | |
Secondary | Change in Calgary Depression Rating Scale for Schizophrenia (CDSS) | Assessment of depressive symptoms in patients with schizophrenia | Change between assessment pre-therapy and assessment after six month of therapy | |
Secondary | Change in Role Functioning Scale (RFS) | Assessment of social functioning | Change between assessment pre-therapy and assessment after six month of therapy | |
Secondary | Change in Paranoia Checklist (PCL) | Assessment of self-reported paranoid delusion frequency, distress and conviction | Change between assessment pre-therapy and assessment after six month of therapy | |
Secondary | Change in Beck Depression Inventory-II | Assessment of self-reported depressive symptoms | Change between assessment pre-therapy and assessment after six month of therapy | |
Secondary | Change in Peters et al. Delusions Inventory | Assessment of self-rated delusion frequency, delusional distress and delusional | Change between assessment pre-therapy and assessment after six month of therapy |
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