Schizophrenia Clinical Trial
Official title:
Mindfulness Group-based Intervention for Early Psychosis: A Pilot Study
Recent research has suggested that mindfulness-based interventions for psychosis may be
effective in reducing the negative symptoms of schizophrenia (e.g., social withdrawal, lack
of motivation) and the distress associated with psychotic symptoms (e.g., hearing voices) and
could lead to improvements in functioning and quality of life. However these findings are
based on small studies that largely consist of patients with chronic illness. Little is yet
known about the use of mindfulness interventions for young people recovering from their first
episode of psychosis.
The purpose of this study is to determine whether the Mindfulness Ambassador Council (MAC), a
12-week facilitated group intervention promoting mindfulness skills and the development of
emotional and social competencies, is an effective, feasible, and acceptable means of
treating youth in the early stages of psychotic illnesses. Although the current study is
hypothesis generating in nature, based on previous investigations of Mindfulness Based
Interventions for psychoses (Chadwick, 2014), we are expecting that participating in the MAC
intervention will result in improvements in clinical, cognitive, functional, and health
service utilization parameters. Additionally, we expect that the MAC intervention will prove
to be acceptable to participants and a feasible intervention for early psychotic disorders.
The purpose of this study is to determine whether the Mindfulness Ambassador Council (MAC), a
12-week facilitated group mindfulness based intervention specifically designed to promote
mindfulness skills and the development of emotional and social competencies in youth, is an
effective, feasible, and acceptable means of treating people in the early stages of psychotic
illnesses.
We intend to randomly assign 30 patients being treated for psychotic illnesses in an early
intervention program to an immediate treatment intervention or a delayed treatment
intervention. Participants assigned to the immediate treatment intervention will receive the
MAC intervention at the onset of the study whereas those assigned to the delay treatment
intervention will receive the MAC intervention after approximately 3 months in a treatment as
usual control group.
Participants will be evaluated at baseline, immediately post-intervention and at 3-month
post-intervention on a number measures. MAC acceptability will be assessed through the Client
Satisfaction Questionnaire and qualitative interviews, MAC feasibility will be assessed
through recruitment, consent and completion rates, and MAC efficacy will be assessed with a
number of clinical, social, cognitive, and mindfulness skill assessment tools as well as
through changes in healthcare utilization before and after administration of the MAC
intervention.
Although the current study is hypothesis generating in nature, based on previous findings of
Mindfulness Based Interventions for psychoses, we are expecting that participation in the MAC
intervention will result in improvements on clinical, cognitive, functional, and health
service utilization parameters. Additionally, we expect that the MAC intervention will be
acceptable to participants and a feasible intervention for early psychotic disorders.
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