Schizophrenia Clinical Trial
Official title:
The Assessment of the Safety, Efficacy, and Practicality of an Algorithm Including Amantadine, Metformin and Zonisamide for the Prevention of Olanzapine-Associated Weight Gain in Outpatients With Schizophrenia
The goal of this study is to answer the following questions:
- Whether treatment with amantadine, metformin or zonisamide can prevent or reverse the
weight gain that is associated with olanzapine
- Whether taking amantadine, metformin or zonisamide can help patients decrease or
eliminate some of the changes in body that occur with weight gain
- How weight gain associated with olanzapine can affect people
- Whether treatment with amantadine, metformin or zonisamide can help eliminate weight
gain associated with olanzapine and not interfere with the positive effects of
olanzapine on functioning of people with schizophrenia and other diseases
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
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