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NCT00178932 Clinical Trial

Improving Outcome in Schizophrenia Through Identification of Genetic Risk Factors

Schizophrenia Clinical Trial

Official title:
Improving Outcome in Schizophrenia Through Identification of Genetic Risk Factors

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00178932
Other study ID # 9132
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date November 1998
Est. completion date December 2023

Study information
Verified date April 2023
Source Northwestern University
Contact Barrett Share, M.A.
Phone 615-936-6796
Email daniel.b.share@vanderbilt.edu
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The goals of this study are to replicate previous findings of genetic predictors of response to clozapine and other antipsychotic drugs.

Recruitment information / eligibility
Status Recruiting
Enrollment 1000
Est. completion date December 2023
Est. primary completion date December 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria: Patients with the diagnoses of schizophrenia or schizoaffective disorder, and bipolar disorder or major depression with psychotic features, or volunteers with no history of a psychotic disorder. Exclusion Criteria: Patients with DSM-IV diagnoses other than schizophrenia or schizoaffective disorder, and bipolar disorder or major depression with psychotic features.

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• genetic analysis
genetic assay of blood sample drawn with patient's consent
• genetic assay
genetic assay of blood sample drawn with patient's consent

Locations
Country Name City State
United States Psychiatric Hospital at Vanderbilt Nashville Tennessee

Sponsors (1)
Lead Sponsor Collaborator
Northwestern University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary We plan to compare the polymorphisms across schizophrenic patients and adults who do not have a diagnosed major mental illness. . single visit
Secondary We will also evaluate relationships between the polymorphism and past and current mental health among the non-diagnosed sample single visit
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