Prospective Recurrent Pregnancy Loss Registry

Status Recruiting

Clinical Trial Summary

The purpose of this Registry is to prospectively collect data of Recurrent Pregnancy Loss (RPL) patients attending the specialized care centre at the BC Women's Hospital, in order to evaluate investigation practices, treatment options, and outcomes for this patient population over time.

Clinical Trial Description

The Recurrent Pregnancy Loss Program at the BC Women's Centre for Reproductive Health is the only tertiary care centre of its kind in British Columbia, and has provided specialized and comprehensive care to RPL patients for the past 15 years. Using a team-based collaborative model, the program provides point-of-care investigations, surgical treatment, clinical management, education, and grief counselling. All RPL patients are asked to complete the intake questionnaire prior to their initial visit at the clinic. If the patient provides their consent to take part in research, their data will be copied from the clinical database to the research database. The questionnaire includes information regarding patient demographics, obstetric history, gynecological history, personal and medical history, family history and partner information. Additionally, data will also be collected from patient charts, follow-up questionnaires sent once a year for the next 5 years following the patient's initial visit, and medical records from fertility clinics and general practitioners when available. The online data registry is housed in the Research Electronic Data Capture (REDCap) platform located at BC Children's Hospital (BCCH). As an optional component of this study, patients invited to join the registry will also be presented with the option to register with the BCCH BioBank to store their tissue samples collected in the RPL clinic for clinical & diagnostic purposes. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05989178
Study type	Observational [Patient Registry]
Source	University of British Columbia
Contact	Mohamed A. Bedaiwy, MD, PhD
Phone	604-875-2000
Email	mohamed.bedaiwy@cw.bc.ca
Status	Recruiting
Phase
Start date	July 12, 2022
Completion date	December 31, 2032

View Details

See also
Status	Clinical Trial	Phase
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Recruiting	`NCT01946945` - Comparison of Standard ART Practice vs. Trophectoderm Biopsy and Whole Chromosome Analysis	Phase 2
Completed	`NCT02572154` - Sperm DNA Fragmentation in Recurrent Pregnancy Loss	N/A
Completed	`NCT03174951` - Immunomodulatory Effects of IVIg on Pregnancy Rate of Patient With Recurrent Pregnancy Loss	Phase 2
Recruiting	`NCT05444283` - Genomic Predictors of Recurrent Pregnancy Loss
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Recruiting	`NCT02990403` - The Novel Immunomodulatory and Anticoagulant Therapies for Recurrent Pregnancy Loss	Phase 4
Recruiting	`NCT02990390` - The Epidemiology of Recurrent Spontaneous Abortion Associated With Thrombophilla	N/A
Not yet recruiting	`NCT05612620` - Elucidating the Microbiome in Patients With Recurrent Pregnancy Loss
Not yet recruiting	`NCT05520112` - Treatment of Recurrent Pregnancy Loss Using Mesenchymal Stem Cells	Phase 1/Phase 2
Suspended	`NCT04397042` - SCUBE-1 and Carotid Intima Media Thickness in Recurrent Pregnancy Loss
Not yet recruiting	`NCT05341856` - Uterine Artery Doppler Changes After Vaginal Administration of Isosorbide Mononitrate In Patients With URPL	Early Phase 1
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Completed	`NCT02386384` - TNFα and MFG-E8: Novel Biomarkers to Predict Implantation Failure	N/A
Recruiting	`NCT01635426` - Aspirin Versus Clopidogrel Effect on Uterine Blood Flow in Women With Unexplained Recurrent Miscarriages	Phase 2/Phase 3
Suspended	`NCT01546350` - Preimplantation Genetic Diagnosis Using Blastocyst Biopsy and Array CGH	Phase 2
Completed	`NCT00721591` - Pharmacokinetics of Low Molecular Weight and Unfractionated Heparin in Pregnancy	N/A
Terminated	`NCT00564174` - Low Molecular Weight Heparin and Aspirin in the Treatment of Recurrent Pregnancy Loss: A RCT	N/A
Completed	`NCT04455256` - Evaluation of Endoplasmic Reticulum Stress in Patients With Recurrent Pregnancy Loss
Not yet recruiting	`NCT05237843` - Hydroxychloroquine in Unexplained Recurrent Pregnancy Loss	Phase 1