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Abortion, Spontaneous clinical trials

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NCT ID: NCT03358940 Completed - Clinical trials for Threatened Miscarriage

Assessment of Non-medical Use of Misoprostol in Case of Miscarriage or Threatened Miscarriage.

MISO
Start date: March 29, 2016
Phase: N/A
Study type: Interventional

Non-medical used of misoprostol for abortion is a growing concern in Guadeloupe. Such situation is reasonable for countries in which abortion is not easy to obtain or prohibited. However regarding the risk of complications, it is less understandable in region like Guadeloupe where legal abortion with medical assistance is accessible for all and free. The aim of the study is to investigate on the amount of misoprostol taken by women in Guadeloupe, by doing an analytical measurement. The aim is to evaluate batter this practice in Guadeloupe, when the main objective of the study is to detect the presence or the absence of misoprostol in the urine sample of the woman coming at hospital for threatened miscarriage or miscarriage complications. Moreover, these abortions can be more important than spontaneous miscarriage.

NCT ID: NCT03354780 Completed - Endometriosis Clinical Trials

Endometriosis and Risk of Miscarriage

Start date: January 15, 2016
Phase: N/A
Study type: Observational

The aim of this study is to compare the rate of miscarriage at first spontaneous pregnancy among women with endometriosis with the rate of miscarriage at first spontaneous pregnancy among women without endometriosis.

NCT ID: NCT03336463 Completed - Clinical trials for Miscarriage, Recurrent

Prediction of Recurrent Pregnancy Loss by a New Thrombophilia Based Genetic Risk Score

TiC-RPL
Start date: February 2015
Phase: N/A
Study type: Observational

Recurrent pregnancy loss (RPL) is a clinical problem affecting 1-5% of couples of reproductive age. The contribution of thrombophilia to RPL is disputed. This controversy is partly due to low sensitivity of the genetic variants currently used to evaluate hereditary thrombophilia: the Leiden mutation (identified as rs6025) in the coagulation factor 5 (F5L) gene and mutation G20210A (identified as rs1799963) in the prothrombin (PT) gene. Our objective was to determine whether a wider algorithm that includes clinic and genetic variants associated with thrombophilia could be more useful in the prediction for RPL than FVL and PT alone.

NCT ID: NCT03332706 Recruiting - Clinical trials for Spontaneous Abortion

the Association Between Blood's and Urinary Heavy Metal Level in Pregnant Women and the Spontaneous Abortion

HMLandSA
Start date: October 10, 2017
Phase: N/A
Study type: Observational

The aim of the study was to define the possible association between heavy iron level and the consequence of pregnancy especially spontaneous abortion and missed abortion. The study population will comprised the first-trimester pregnant women in the PUMCH (Peking Union Medicine College Hospital) during 2017 October to 2018 November. We categorised the patients into two groups, the study group where the patients suffered from spontaneous abortion or missed abortion, and the control group where the patients carry the normal live fetal for at least 8 weeks and ask for artificial abortion. All the cases included in the study were examined with respect to 6 kinds of heavy iron level in venous blood and urine, then correlation analysis was applied to define heavy iron level between two groups.

NCT ID: NCT03327766 Not yet recruiting - Clinical trials for vitD3 Level in Cases of Recuurent Pregnancy Loss

Assesment of Vit D3 Level in Cases of Unexplaind Pregnancy Loss in Assiut

vitDinRPL
Start date: November 1, 2017
Phase: N/A
Study type: Observational

Assesment of Vit D3 leve in cases of unexplained recurrent pregnancy loss in assiut

NCT ID: NCT03320213 Completed - Clinical trials for Threatened Miscarriage in First Trimester

Value of CA125 and Yolk Sac Morphology in Prediction of Pregnancy Outcome in Threatened Miscarriage

Start date: October 1, 2016
Phase: N/A
Study type: Observational

evaluation of serum CA125 level and yolk sac morphology in women with threatened miscarriage is very important to predict pregnancy outcome

NCT ID: NCT03309735 Recruiting - Clinical trials for Threatened Miscarriage

Non-interventional Study of Therapy for Threatened Miscarriage

Start date: October 16, 2017
Phase: N/A
Study type: Observational

Study the efficacy and safety of therapy for threatened miscarriage with medicinal products Utrogestan (micronized progesterone), 200 mg capsules (Besins Healthcare SA, Belgium), and Duphaston (Dydrogesterone), 10 mg coated tablets (Abbott Healthcare Products B.V., the Netherlands)

NCT ID: NCT03305263 Not yet recruiting - Clinical trials for Recurrent Pregnancy Loss

Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss

Start date: October 2017
Phase: Phase 3
Study type: Interventional

Recurrent pregnancy loss (RPL) defined as 3 or more pregnancy losses affects approximately 3% of couples trying to achieve parenthood. Most cases of RPL are unexplained and have no effective treatment to improve the chance of a live birth. Exciting indications for using Hydroxychloroquine (HCQ) include: Malaria profylaxis and treatment, systemic and discoid lupus erythematosus (SLE) and rheumatoid athritis. HCQ has been reported to have the following properties (anti-thrombotic, vascular-protective, immunomodulatory, improving glucose tolerance, lipid-lowering, and anti-infectious). There is no data concerning the benefit of HCQ in RPL. Administration for other indications provides extensive safety data during pregnancy. This study has the potential to establish support for a new treatment option for unexplained RPL.

NCT ID: NCT03220750 Recruiting - Clinical trials for Abortion, Spontaneous

University Hospital Advanced Age Pregnant Cohort

UNIHOPE
Start date: March 28, 2017
Phase: N/A
Study type: Observational

The University Hospital Advanced Age Pregnant (UNIHOPE) Cohort is the major part of the National Key Research and Development Program on Reproductive Health & Major Birth Defects Control and Prevention Project, which is funded by the Ministry of Science and Technology of China. The Project is led by Prof. Zhao Yangyu, from the Department of Gynecology & Obstetrics, Peking University Third Hospital, and the UNIHOPE cohort is led by Prof. Jian-meng Liu, the Co-PI of the Project.

NCT ID: NCT03218878 Recruiting - Infertility Clinical Trials

Pregnancy Outcomes After Uterine Cavity Expansion

Start date: July 21, 2017
Phase: N/A
Study type: Observational

This study seeks to evaluate pregnancy outcomes following hysteroscopic uterine cavity expansion surgery for patients with dysmorphic uterine cavities and poor reproductive histories. Patients already planning to undergo surgery at the recommendation of their physicians will be recruited for participation.