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Quality of Life clinical trials

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NCT ID: NCT03549039 Completed - Quality of Life Clinical Trials

Effect of Alveolar Bone Grafting

Start date: June 30, 2018
Phase:
Study type: Observational

This study included patients who underwent secondary alveolar bone grafting by harvesting graft from the anterior iliac crest, in Oral and Maxillofacial Department, Faculty of Dentistry, Ankara University, Turkey, during the period from January 2012 to March 2016. All patients were operated using the same technique and by the same surgical team. Patients will be interviewed to fill Short-Form Health Survey (SF-12) and Postsurgical Patient Satisfaction Questionnaire (PSPSQ) 6 months postoperatively. The questionnaires will be used to assess the relationship between health quality and patient satisfaction. Also, grafted sites will be evaluated with respect to fistula, the presence of cleft palate, and infection.The descriptive statistics and Pearson correlation analyses will be made using PSPSQ scores and SF-12 PCS and MCS scores.

NCT ID: NCT03538249 Completed - Heart Failure Clinical Trials

Effects of Rehabilitation in Patients With Stable Chronic Heart Failure

Start date: January 2015
Phase: N/A
Study type: Interventional

Heart failure (HF) is a major public health problem. This is the first cause of hospitalization and mortality of about 65 years old. This syndrome is characterized by a poor prognosis and a high cost of care. Thus, new strategies for treatment and prevention of the HF are among the major challenges facing health sciences today. The management of HF requires multimodal approach it involves a combination of non-pharmacological and pharmacological treatment, Besides improvements in pharmacological treatment, supervised exercise programs are recommended for all patients with HF as part of a non-pharmacological management but many questions regarding exercise training in HF patients remain unanswered. Even simple questions such as the best mode of training for these patients are unclear. The aim of this study 1. First, to characterize the physiological functions involved in the genesis of exercise intolerance and dyspnea especially muscle function (respiratory and skeletal), and cardiopulmonary patients suffering from chronic HF. 2. Second, to study and compare the effects of different rehabilitation programs and prove the superiority of the combination of three training modalities program: aerobic training (AT), resistance training (RT) and inspiratory muscle training (IMT). These modalities are: Aerobic Training: It has been proven effective in improving muscle abnormalities on changing the ventricular remodeling, dyspnea, functional capacity, increasing the maximum performance and reducing hospitalization in subjects suffering HF. Resistance Training: It has been proven effective in improving skeletal muscle metabolism and angiogenesis; increasing capillary density and blood flow to the active skeletal muscles, promoting the synthesis and release of nitric oxide, and decreasing oxidative stress. Selective Inspiratory Muscle Training: It has been proven effective in improving the strength and endurance of the respiratory muscles and reduction of dyspnea during daily activities.

NCT ID: NCT03533062 Completed - Quality of Life Clinical Trials

Trigonal vs Non Trigonal Botox Injection in OAB.

Start date: June 14, 2015
Phase: N/A
Study type: Interventional

The investigators attend to conduct a prospective randomized study to assess safety and efficacy of trigonal-involved vs. trigonal-sparing botox injection technique, quality of life measurement and post-injection anticholinergics use efficacy. Assessing safety by identification of side effects like constipation, urine retention....etc. efficacy is measured using Over Active Bladder Symptoms Score(OABSS) and urodynamics measures after 6 months follow up.

NCT ID: NCT03529864 Completed - Quality of Life Clinical Trials

Effects of Therapeutic Exercise on Quality of Life

Start date: October 3, 2014
Phase: N/A
Study type: Interventional

The main objective was to determine the efficacy and safety of a therapeutic exercise program for students. Secondary objectives, determine the prevalence and intensity of musculoskeletal pain (MSP), disability, Health-Related Quality of Life (HRQOL), and satisfaction and perceived improvement with program.

NCT ID: NCT03525327 Completed - Quality of Life Clinical Trials

University of Southern California Choreographic Institute Line Dance Study

USCCILDS
Start date: September 25, 2017
Phase:
Study type: Observational

This study will include dance protocols for targeted therapeutic interventions measuring the effect of line dancing on cognitive, emotional and social well-being. The hypothesis is that participating in a one-hour line dance class once a week for twelve weeks will decrease stress levels and enhance participants' quality of life, as measured by interview survey questionnaires. Questionnaires will be administered at the beginning, mid-point, and end of the study. The objectives of the study are threefold: to quantify the beneficial effects of line dancing on quality of life including cognitive, emotional and social well-being; to identify how non-lifetime, amateur dance practitioners can benefit from dancing; and to demystify dance class and make it accessible to people who are not interested in learning a specific dance technique or concert/art dance. Line dancing is a cross-cultural, intergenerational activity that could fill this role.

NCT ID: NCT03514147 Completed - Quality of Life Clinical Trials

Pelvic Floor Muscle Training on the Quality of Life in Women With Urinary Incontinence

Start date: October 2015
Phase: N/A
Study type: Interventional

Aim: To assess the influence of pelvic floor muscles group training in the quality of life and functionality of these muscles in women with UI. Study design: This is a randomized controlled trial.

NCT ID: NCT03505866 Completed - Depression Clinical Trials

Community Home-based Care Intervention and Its Health Outcome in HIV-positive People

HIV
Start date: March 1, 2015
Phase: N/A
Study type: Interventional

An intervention study was designed to examine the impact of impact of community home-based care intervention on mental health and treatment outcome in HIV-positive people. The intervention comprised a home-based counseling on anti-retroviral therapy (ART) adherence, psycho social support, basic health care services at the home of HIV-positive people. The intervention started in March, 2018 and completed in August 2018. The major measurements of the interventions were ART adherence, status of depression, anxiety, and stress levels.

NCT ID: NCT03503838 Completed - Cancer Clinical Trials

A Pilot Study of Online Yoga for MPN Patients

Start date: September 23, 2016
Phase: N/A
Study type: Interventional

Polycythemia vera (PV), essential thrombocytosis (ET), and myelofibrosis (MF) are chronic Philadelphia negative myeloproliferative neoplasms (MPNs) that are characterized by clonal proliferation of hematopoietic stem cells, intramedullary fibrosis, and splenomegaly. While disease manifestations may vary amongst the spectrum of MPNs, quality of life considerations including fatigue, concentration difficulties, pain, sleep disturbance, and depression are negatively affected in most MPN patients. Inflammation has been suggested to be involved in the development of disease-related symptoms. Specific pro-inflammatory cytokines (e.g., IL-1, IL-6, IL-8, and TNF-α) have been associated with particular patient-reported symptoms, including fatigue, abdominal complaints, microvascular symptoms, and constitutional symptoms. Pharmacologic therapy can positively impact MPN related symptoms, specifically with JAK inhibition, however, these treatments often come with negative side effects (e.g., anemia, thrombocytopenia). Much opportunity remains for improving MPN symptoms (i.e., fatigue, insomnia, loss of muscle mass, and debilitation) and quality of life. Yoga, a gentle form of meditative exercise, has been shown to improve symptom management and quality of life parameters in cancer patients and may be effective in improving MPN-related symptoms. Here we propose a study evaluating the efficacy of an online yoga intervention comparing a yoga group to a wait-list control group for improving symptom burden and quality of life in MPN patients. Secondarily, we plan to evaluate the feasibility of collecting potential biomarkers that are related to MPN disease-related activity, such as fatigue (i.e., cortisol and serum cytokines).

NCT ID: NCT03495518 Completed - Quality of Life Clinical Trials

Enabling Symptom Identification and Tracking in Children Receiving Cancer Treatment

Start date: July 2, 2018
Phase: N/A
Study type: Interventional

Children with cancer and hematopoietic stem cell transplant (HSCT) recipients suffer from severe and bothersome symptoms because treatments are intense. So, the investigators developed SPARK (Supportive care Prioritization, Assessment and Recommendations for Kids), a website devoted to helping children track symptoms and providing a way to let doctors and nurses know which symptoms are bothersome. This study will examine the likelihood that children will complete SPARK once daily, help the investigators figure out how to improve the website so that children will use it, and help the investigators plan the large scale trial to test its efficacy in improving quality of life (QoL). Participants will be children with cancer or HSCT recipients who are 8-18 years of age and who are expected to be in hospital or in clinic daily for 5 days.To determine the feasibility of a randomized controlled trial (RCT) of symptom feedback to healthcare providers

NCT ID: NCT03488264 Completed - Quality of Life Clinical Trials

Stigma, Self-management, & Quality of Life in SCD

SSQ
Start date: February 13, 2018
Phase:
Study type: Observational

Many individuals with sickle cell disease experience both a poor quality of life and stigma. Individuals with SCD often experience high levels of stigma which can be a barrier to good self-management and hinder quality of life. The purpose of this research is to improve understanding of the relationships between stigma, self-management, and quality of life in SCD in the United States and Jamaica. The findings from this project will contribute to the development of a tool to measure self-management strategies and will also guide the development of interventions to improve SCD self-management.