The Effects of Progressive Muscle Relaxation Therapy in Patients With Schizophrenia

Psychotic Disorder Clinical Trial

Official title:

The Effects of Progressive Muscle Relaxation Therapy in Patients With Schizophrenia: Randomized Controlled Trials

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03667729
• Other study ID #: C20140205
• Status: Completed
• Phase: N/A
• Start date: June 30, 2014
• Est. completion date: June 29, 2015

Study information

• Verified date: June 2017
• Source: Taipei Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study applied a randomized parallel case-controlled design. The study purpose was to evaluate the effects of progressive muscle relaxation on anxiety, psychiatric symptoms and quality of life among patients with chronic schizophrenia compared with an active control.

Description:

Background: Anti-psychotic drugs are limited in their ability to improve psychiatric symptoms, quality of life, and anxiety status in patients with chronic schizophrenia. Progressive Muscle Relaxation (PMR) can potentially reduce anxiety status and improve subjective welling in acute patients. It is an ideal rehabilitation intervention for patients with chronic schizophrenia. However, no study has investigated the effects of PMR on outcomes among patients with chronic schizophrenia.

Design: This study applied a randomized parallel case-controlled design.

Methods: Hospital-based randomized control trial in Taiwan. Eighty subjects with chronic schizophrenia were recruited from a psychotic ward and randomized into PMR, or control groups. Patients in the intervention group participated in progressive muscle relaxation for 12 weeks; while patients in the control group members received supportive treatment-as-usual (TAU). All participants completed anxiety, psychotic syndromes and quality of life measures at baseline, 3-month, and 3-month follow-up.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 75
• Est. completion date: June 29, 2015
• Est. primary completion date: June 29, 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 65 Years

Eligibility

Inclusion Criteria:

• Clinical diagnosis of Schizophrenia

• Without the risk of self-injury and violence

• Patients aged from 20-65 years old

• Had no alcohol and drug abuse

• Can use Mandarin or Taiwanese to communicate

Exclusion Criteria:

• Patients with another psychiatric comorbidity

• Patients with musculoskeletal problems

• patients who cannot sit last for 50 minutes

• Had received progressive muscle relaxation training within the last year

• Diagnosis of confirmed cardiovascular disease

Related Conditions & MeSH terms

• Affective Disorders
• Disease
• Mental Disorders
• Mood Disorders
• Psychotic Disorder
• Psychotic Disorders
• Schizophrenia

Intervention

Behavioral:
• progressive muscle relaxation
intervention group: The experimental group received muscle relaxation training once a week for 3 consecutive months. The results were measured and followed up after 3 months.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Taipei Medical University

References & Publications (42)

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* Note: There are 42 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Quality of life simplified Chinese versions of the WHOQOL-BREF questionnaire were used	a 28-item questionnaire rated on a five-point Likert scale with four domains measuring: psychological health, physical health, social relationships and environment.so that higher scores refer to high QOL.	Measuring changes in quality of life from baseline to 6 months.
Secondary	Anxiety Scale	State anxiety was assessed by the State anxiety inventory (SAI) of Spielberg (1984). The range of possible total scores is 20-80. Higher scores indicate higher levels of anxiety.	measured at baseline, 3-month, and 3-month follow-up
Secondary	Positive and Negative Syndrome Scale (PANSS)	The instrument was developed by Kay et al. (1987) to assess psychopathology of schizophrenia which includes: positive, negative, general psychopathology symptoms.	measured at baseline, 3-month, and 3-month follow-up