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Prostatic Neoplasms clinical trials

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NCT ID: NCT05960669 Completed - Prostate Cancer Clinical Trials

Nerve-sparing, Robot-assisted Radical Prostatectomy Using a Personalized, 3D-printed Prostate Model for Selective Resection of Positive Surgical Margins

AURORA
Start date: August 1, 2018
Phase: N/A
Study type: Interventional

To optimize precision for secondary resection (SR) in frozen section (FS) controlled nerve-sparing robot-assisted radical prostatectomy (NS-RARP) by using a personalized 3D-printed prostate model.

NCT ID: NCT05886751 Completed - Prostate Cancer Clinical Trials

Randomized Trial of Trust in Online Videos About Prostate Cancer

Start date: August 18, 2021
Phase: N/A
Study type: Interventional

The study team will evaluate the impact of video characteristics on health consumers' trust in online videos. Participants will be randomized to watch a video by one of four speakers about prostate cancer screening or clinical trials and complete a questionnaire (approximately 15 minutes total).

NCT ID: NCT05880446 Completed - Prostate Cancer Clinical Trials

PROstate CAncer Radiotherapy - Bowel Quality of Life (PROCAR-BQ)

PROCAR-BQ
Start date: October 6, 2023
Phase: N/A
Study type: Interventional

This is a prospective pilot study to evaluate the mean increase of bowel symptoms after pelvic radiotherapy (RT) in prostate cancer (PCa) patient using the validated & newly translated EORTC-QLQ PRT20 module.

NCT ID: NCT05834270 Completed - Prostatic Neoplasms Clinical Trials

Single Dose Versus Double Dose Tamsulosin in Management of Moderate and Severe LUTS Due to BPH

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Single dose versus double dose tamsulosin in Management of Moderate and severe lower urinary tract symptoms due to benign prostatic hyperplasia

NCT ID: NCT05820113 Completed - Prostate Cancer Clinical Trials

Deep Learning Super Resolution Reconstruction for Fast and Motion Robust T2-weighted Prostate MRI

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study was therefore to investigate a new unrolled DL super resolution reconstruction of an initially low-resolution Cartesian T2 turbo spin echo sequence (T2 TSE) and compare it qualitatively and quantitatively to standard high-resolution Cartesian and non-Cartesian T2 TSE sequences in the setting of prostate mpMRI with particular interest in image sharpness, conspicuity of lesions and acquisition time. Furthermore, the investigators assessed the agreement of assigned PI-RADS scores between deep learning super resolution and standard sequences.

NCT ID: NCT05806853 Completed - Prostate Cancer Clinical Trials

PET/MR for Prostate Cancer Restaging: a Phase II Prospective Monocentric Study

Start date: June 3, 2020
Phase: Phase 2
Study type: Interventional

The overall goal is to provide an innovative approach to restage patients with biochemical recurrence of prostate cancer by using hybrid PET/MR with innovative radiotracers (68Ga-PSMA and 68Ga-RM2)

NCT ID: NCT05803096 Completed - Prostate Cancer Clinical Trials

Self-Administered Nitrous Oxide (SANO) During Transrectal Prostate Biopsy to Reduce Patient Anxiety and Pain

Start date: December 12, 2021
Phase: Phase 4
Study type: Interventional

Transrectal prostate biopsy is a commonly performed ambulatory procedure for diagnosing prostate cancer. Prostate biopsy are associated with pain or anxiety. Nitrous oxide (or laughing gas) is a well-known inhaled anesthetic which is frequently used in dental offices and for pediatric procedures to alleviate a patient's anxiety and pain. This study seeks to determine whether administration of nitrous oxide at the time of prostate biopsy will improve a patient's experience of care.

NCT ID: NCT05800483 Completed - Prostate Cancer Clinical Trials

Improving Decision-Making for Low Health Literate Prostate CA Patients

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

This study used a randomized controlled trial to evaluate whether Healium (designed to target preference elicitation) is as efficacious as Healing Choices (a comprehensive education and decision tool) in improving outcomes for decision-making and emotional quality of life.

NCT ID: NCT05797727 Completed - Breast Cancer Clinical Trials

Real-Life Pilot Feasibility Study (LC_RLP)

LC_RLP
Start date: January 15, 2023
Phase: N/A
Study type: Interventional

The LifeChamps Real-Life pilot's objective is to ascertain the feasibility of the use of the LifeChamps solution, previously developed in another clinical trial, in a real-world environment. This solution integrates a health advisory system, and technical intelligence, based on behavioural science, to provide personalized recommendations to follow a healthier lifestyle, to act as a nutrition and physical activity coach, and to guide on social inclusion, among other issues, with the aim of increasing the quality of life. This study is conducted to investigate the feasibility of such an undertaking, assess the clinical impact it may have, as well as evaluate the applicability, usability, and effectiveness of the solution.

NCT ID: NCT05773703 Completed - Prostate Cancer Clinical Trials

Exploratory PK and Imaging Study of PSMA-Targeted Trillium Compounds and PTI-122 in Metastatic Prostate Cancer

Start date: December 8, 2022
Phase: Early Phase 1
Study type: Interventional

Exploratory study in adult males with metastatic prostate cancer intended to characterize the pharmacokinetics and biodistribution of PSMA-Targeted [In-111]-Labeled Trillium Compounds with and without the cytoprotective agent PTI-122. Up to 36 eligible subjects will be enrolled. Additional subjects may be enrolled if there is insufficient data for evaluation, for example if the original study subjects do not complete required imaging studies for reasons unrelated to adverse events. Up to four PSMA-Targeted [In-111]-Labeled Trillium Compounds will be evaluated. Each compound will be evaluated first without the cytoprotective agent, PTI-122, then the [In-111]-labeled Trillium Compound may be co-administered with PTI-122.