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Prostatic Neoplasms clinical trials

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NCT ID: NCT00392938 Completed - Prostate Cancer Clinical Trials

Carbon-11 Acetate and Fludeoxyglucose F 18 PET Scan of the Bone in Patients With Metastatic Prostate Cancer That Has Spread to the Bone

Start date: December 2005
Phase: N/A
Study type: Observational

RATIONALE: Imaging procedures, such as PET scan, may help doctors predict a patient's response to treatment and help plan the best treatment. PURPOSE: This clinical trial is studying carbon-11 acetate and fludeoxyglucose F 18 PET scan of the bone in patients with metastatic prostate cancer that has spread to the bone.

NCT ID: NCT00391690 Completed - Prostate Cancer Clinical Trials

Evaluation of Bone Markers as Diagnostic Tools for Early Detection of Bone Metastases in Patients With High Risk Prostate Cancer

Start date: February 2006
Phase: Phase 4
Study type: Interventional

It is the aim of this prospective, single-group, clinical study to assess whether bone parameters can be used as diagnostic tools for early detection of bone metastases in patients with high risk prostate cancer. The usefulness in monitoring zoledronic acid therapy in patients who have developed bone metastases will also be assessed.

NCT ID: NCT00390468 Completed - Prostate Cancer Clinical Trials

Tandutinib in Treating Patients With Progressive Prostate Cancer and Bone Metastases

Start date: October 2006
Phase: Phase 2
Study type: Interventional

RATIONALE: Tandutinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase II trial is studying how well tandutinib works in treating patients with progressive prostate cancer and bone metastases.

NCT ID: NCT00385580 Completed - Prostate Cancer Clinical Trials

Phase II Study of Dasatinib (BMS-354825) for Androgen-deprived Progressive Prostate Cancer

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to learn if men with metastatic prostate cancer and rising Prostate Specific Antigen (PSA), who have been surgically castrated or are undergoing androgen deprivation with Luteinizing Hormone Releasing Hormone (LHRH) treatment, respond to dasatinib. The safety of this treatment will also be studied.

NCT ID: NCT00384839 Completed - Prostate Cancer Clinical Trials

Vidaza to Restore Hormone Thx Prostate

Start date: April 2006
Phase: Phase 2
Study type: Interventional

The purpose of this research study is to find out what effects (good and bad) Vidaza has on patients with prostate cancer. This investigational drug is not approved by the Food and Drug Administration (FDA) for the treatment of prostate cancer; however, it is approved in myelodysplastic syndrome - a bone marrow disease. The pharmaceutical company involved in this study, Pharmion Corporation, is the manufacturer of Vidaza.

NCT ID: NCT00381966 Completed - Prostate Cancer Clinical Trials

Study of Robotic Template Guidance for Needle Placement in Transperineal Prostate Brachytherapy

J0511
Start date: June 2006
Phase: N/A
Study type: Interventional

This is a study that will try see if a device can help to better guide the needle that places prostate cancer treatment.

NCT ID: NCT00381173 Completed - Breast Cancer Clinical Trials

A Study of ZYC300 Administered With Cyclophosphamide Pre-Dosing

Start date: November 2006
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the feasibility, safety, and tolerability of administering ZYC300 with Cyclophosphamide (Cytoxan).

NCT ID: NCT00379561 Completed - Prostate Cancer Clinical Trials

PSA-Activated PSA-PAH1 for Locally Recurrent Prostate Cancer

Start date: March 2006
Phase: Phase 1
Study type: Interventional

This Phase 1 trial will evaluate the safety and tolerability of PSA-Activated PSA-PAH1 in subjects who have shown biochemical failure and have either completed at least one primary radiation therapy for prostate cancer and have evidence of recurrent local prostate cancer without metastases.

NCT ID: NCT00379132 Completed - Breast Cancer Clinical Trials

131-I-TM-601 Study in Adults With Solid Tumors

Start date: August 2006
Phase: Phase 1
Study type: Interventional

This study is designed to evaluate the ability of intravenously (IV)administered 131-I-labeled TM-601 (chlorotoxin) to provide tumor-specific localization(via radiographic imaging) in patients with recurrent or refractory primary solid tumors with evidence of metastatic involvement. (Refractory tumors are non-responsive to standard treatment.) The safety and tolerability of IV administered 131-I-TM-601 in this patient population will be evaluated as part of this study.

NCT ID: NCT00378690 Completed - Prostate Cancer Clinical Trials

A Phase IIIb Study of Intermittent Versus Continuous Hormone Deprivation Treatment With ELIGARD

ICELAND
Start date: March 2006
Phase: Phase 3
Study type: Interventional

Phase IIIb, Open-label, randomized, controlled multi-centre study. Induction therapy phase for 6 months where all subjects receive 2 ELIGARD depot injections. Those subjects with hormone responsive prostate cancer will be randomized and will receive either intermittent or continuous ELIGARD treatment for 36 months. Following this treatment period, subjects will enter a long-term follow-up period for 48 months.