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Prostatic Neoplasms clinical trials

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NCT ID: NCT00541281 Completed - Clinical trials for Metastatic Prostate Cancer

Safety and Efficacy Study of of Docetaxel vs Docetaxel Estramustine in Hormone Refractory Prostatic Cancer

Start date: December 2003
Phase: Phase 2
Study type: Interventional

we propose to randomize patients with hormone resistant prostate cancer between docetaxel/estramustine/prednisone and docetaxel/prednisone in a phase II study. The principal endpoint will be the efficacy in term of PSA response.

NCT ID: NCT00541047 Completed - Prostate Cancer Clinical Trials

RADICALS - Radiotherapy and Androgen Deprivation In Combination After Local Surgery

Start date: November 2007
Phase: Phase 3
Study type: Interventional

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Androgens can cause the growth of prostate cancer cells. Androgen deprivation therapy, such as goserelin, leuprolide, or bicalutamide, may lessen the amount of androgens made by the body. Giving radiation therapy together with androgen deprivation therapy may kill more prostate cancer cells. PURPOSE: This randomized phase III trial is studying how well giving radiation therapy together with androgen deprivation therapy works in treating patients who have undergone surgery for prostate cancer.

NCT ID: NCT00540059 Completed - Prostate Carcinoma Clinical Trials

Evaluation of QoL, Tolerability and Use of Zoladex 10,8 SafeSystem for Advanced PCa - German IPEP Trial

Start date: June 2005
Phase: N/A
Study type: Observational

Purpose of this study is the evaluation of QoL, tolerability and use of Zoladex 10,8 SafeSystem for advanced PCa under naturalistic conditions

NCT ID: NCT00538668 Completed - Prostate Cancer Clinical Trials

Radioimmunotherapy in Prostate Cancer Using 177Lu-J591 Antibody

Start date: August 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to test the safety of the experimental drug, 177Lu-J591 and see what effects (good and bad) it has on your prostate cancer. Another purpose is to find the highest dose of the drug that can be given without causing severe side effects.

NCT ID: NCT00537381 Completed - Prostatic Neoplasms Clinical Trials

An Efficacy and Safety Study of Intetumumab (CNTO 95) in Participants With Metastatic Hormone Refractory Prostate Cancer

Start date: May 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the effects of intetumumab when given in combination with docetaxel and prednisone to participants with metastatic (spread of cancer cells from one part of the body to another) hormone-refractory (not responding to treatment) prostate cancer (abnormal tissue that grows and spreads in the body until it kills).

NCT ID: NCT00536653 Completed - Osteoporosis Clinical Trials

Changes in Bone Mineral Density and Fracture Risk in Patients Receiving Androgen Deprivation Therapy for Prostate Cancer

Start date: October 1999
Phase: N/A
Study type: Interventional

The aim of this study is to determine the long term effects of two types of hormonal treatment for advanced prostate cancer (LHRH agonists and the antiandrogen bicalutamide)on the bone mineral density of patients.

NCT ID: NCT00535834 Completed - Prostate Cancer Clinical Trials

Studying Stored Samples From Patients With Localized Prostate Cancer Treated on Clinical Trial NCI-00-C-0154

Start date: n/a
Phase: N/A
Study type: Observational

RATIONALE: Studying samples of blood in the laboratory from patients before and after treatment may help doctors learn more about the effects of the treatment on cells. PURPOSE: This clinical trial is studying samples collected from patients with localized prostate cancer who received treatment on clinical trial NCI-00-C-0154.

NCT ID: NCT00534196 Completed - Prostate Cancer Clinical Trials

Implant Radiation Therapy Using Radioactive Iodine in Treating Patients With Localized Prostate Cancer

J-POPS
Start date: July 2005
Phase:
Study type: Observational

RATIONALE: Implant radiation therapy delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. PURPOSE: This clinical trial is studying the side effects and how well implant radiation therapy using radioactive iodine works in treating patients with localized prostate cancer.

NCT ID: NCT00528866 Completed - Prostate Cancer Clinical Trials

Radiation Therapy, Androgen Suppression, and Docetaxel in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy

Start date: April 2008
Phase: Phase 2
Study type: Interventional

RATIONALE: Specialized radiation therapy that delivers a high-dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as leuprolide, goserelin, flutamide, or bicalutamide, may lessen the amount of androgens made by the body. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving radiation therapy together with androgen suppression and docetaxel after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase II trial is studying how well giving radiation therapy together with androgen suppression and docetaxel works in treating patients with high risk prostate cancer who have undergone radical prostatectomy.

NCT ID: NCT00524680 Completed - Prostate Cancer Clinical Trials

Vitamin D in Treating Patients With Prostate Cancer

Start date: June 2007
Phase: Phase 2
Study type: Interventional

RATIONALE: Vitamin D may be effective in treating patients with prostate cancer. PURPOSE: This randomized phase II trial is studying how well 4 different doses of vitamin D works in treating patients with prostate cancer.