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Prostatic Neoplasms clinical trials

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NCT ID: NCT00833248 Completed - Prostate Cancer Clinical Trials

Neoadjuvant Study Investigating Degarelix in Patients Suffering From Prostate Cancer

Start date: April 2009
Phase: Phase 3
Study type: Interventional

The purpose of this phase 3B trial was to see how well a new trial drug (degarelix) works in terms of reducing the size of the prostate volume in prostate cancer patients who were scheduled to undergo subsequent radiotherapy for treatment of their prostate cancer. Prior to receiving radiotherapy, it is recommended that patients with intermediate to high risk prostate cancer are pre-treated with hormone therapy (so-called neoadjuvant therapy) which is known to reduce the size of the prostate and thereby decrease the required radiation field and enable a more safe and effective treatment. In this trial, participants were randomly selected (like flipping a coin) to receive either degarelix given alone or a standard hormone therapy (combination of goserelin and bicalutamide. The treatment was given for three months and the prostate size was measured by ultra sound at the beginning and at the end of the trial. The participants were required to come to the clinic for 5 or 6 visits during the three months.

NCT ID: NCT00831792 Completed - Prostate Cancer Clinical Trials

TKI258 in Castrate Resistant Prostate Cancer

Start date: April 7, 2010
Phase: Phase 2
Study type: Interventional

The goal of this clinical research study is to learn if a decrease in the levels of prostate specific antigen (PSA) may be linked with the status of prostate cancer that has spread to the bones. Researchers also want to learn how changes in your blood PSA level might affect the rebuilding of healthy bones while you are being treated with TKI258 for prostate cancer.

NCT ID: NCT00831623 Completed - Prostate Cancer Clinical Trials

Study of Hypofractionated Proton Beam Radiation Therapy for Prostate Cancer

Start date: February 17, 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine hypofractionated conformal proton beam radiation therapy of prostate cancer can achieve similar treatment benefits as our current institutional standard with conventional fractionation.

NCT ID: NCT00831467 Completed - Clinical trials for Hormonal Refractory Prostate Cancer

Safety and Efficacy Trial of a RNActive®-Derived Prostate Cancer Vaccine in Hormone Refractory Disease

Start date: January 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of a new vaccine in hormone refractory prostate cancer

NCT ID: NCT00830635 Completed - Breast Cancer Clinical Trials

Multimedia Educational Program for Patients With Early-Stage Prostate Cancer or Breast Cancer

Start date: September 2008
Phase: N/A
Study type: Interventional

RATIONALE: A multimedia educational program may help patients with newly diagnosed prostate cancer and breast cancer reduce distress, make informed treatment decisions, and improve quality of life. PURPOSE: This randomized clinical trial is studying how well a multimedia educational program works in patients with early-stage prostate cancer or breast cancer.

NCT ID: NCT00828633 Completed - Prostate Cancer Clinical Trials

Health-Related Quality of Life in Gay Men With Localized Prostate Cancer

Start date: August 2008
Phase: N/A
Study type: Observational

RATIONALE: Gathering information about prostate cancer, treatment, and quality of life from gay men with prostate cancer may help doctors plan the best treatment. PURPOSE: This clinical trial is collecting information about health-related quality of life from gay men with localized prostate cancer.

NCT ID: NCT00828308 Completed - Prostate Cancer Clinical Trials

Neoadjuvant Weekly Ixabepilone for High Risk, Clinically Localized Prostate Cancer

Start date: February 2009
Phase: Phase 2
Study type: Interventional

Ixabepilone, 16 mg/m2 or 20mg/m2, weekly x 3, in 4 week cycles, x 4 cycles. Prostatectomy 2-8 weeks after completion(standard of care and not a part of study)

NCT ID: NCT00822952 Completed - Prostatic Neoplasms Clinical Trials

Prostate Mechanical Imager (PMI) Clinical Bridging Study

PMI
Start date: October 2008
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate an imaging capability Prostate Mechanical Imager (PMI), a PC-based device utilizing a transrectal probe with pressure sensor arrays and motion tracking system, aimed at providing composite elasticity images of the prostate.

NCT ID: NCT00822510 Completed - Prostate Cancer Clinical Trials

Telephone Counseling: Men With Prostate Cancer & Partners

Start date: September 2006
Phase: Phase 1
Study type: Interventional

The purpose of this project is to test a telephone delivered educational support program versus an education only program for improving symptom management and quality of life in men with prostate cancer and their partners.

NCT ID: NCT00819247 Completed - Prostate Cancer Clinical Trials

The Efficacy and Safety of FE 200486 in Treatment of Patients Suffering From Prostate Cancer

Start date: March 2001
Phase: Phase 2
Study type: Interventional

The purpose of this trial was to select a dose of degarelix (FE 200486). Three groups of patients were treated for six months on different doses. The patients had blood samples taken and measured for Testosterone in order to determine the most efficient dose to provide fast and sustained castration. The patients came to the clinic for 16 visits and dependent on the blood sample results they were invited to return for additional blood samples on a two weekly basis.