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Prostatectomy clinical trials

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NCT ID: NCT02924974 Completed - Clinical trials for Patient Satisfaction

Spinal Morphine in Robotic Assisted Radical Prostatectomy

SALMON-RARP
Start date: September 2016
Phase: Phase 4
Study type: Interventional

This study will investigate if a single shot of spinal morphine will increase patient satisfaction when compared to intravenous morphine in Robot-Assisted Radical Prostatectomy

NCT ID: NCT02369211 Completed - Pain Clinical Trials

Pharmacoeconomics and Related Patient Outcomes of Multi-dose Intravenous Acetaminophen (OFIRMEV)

Start date: September 2015
Phase: Phase 4
Study type: Interventional

To examine pharmacoeconomics of IV acetaminophen (Ofirmev). Specifically, to examine its potential to improve hospital efficiency and patient outcomes. The investigators compare the addition of IV acetaminophen versus placebo on postoperative anesthesia care unit recovery times, inpatient hospital length of stay (LOS), postoperative pain scores, consumption of opiates as rescue agents and side effects among patients undergoing robotic-assisted laparoscopic prostatectomy (RALP).

NCT ID: NCT01625572 Completed - Pain Clinical Trials

Ultrasound-assisted Bilateral Transversus Abdominis Plane Block for Open Prostatectomy

TAPPro
Start date: July 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the quality of a transversus abdominis plane blockade with an intravenous pain therapy with opioids. Due to the relatively low side effect profile and comparably few contraindications, this method offers a good option, to be a standard procedure or better alternative in the treatment of pain in surgery of the prostate.

NCT ID: NCT01582477 Completed - Analgesia Clinical Trials

TAP-patients With Robotic Assisted Lap Prostatectomy

TAP
Start date: March 2012
Phase: Phase 4
Study type: Interventional

The purpose of the study is to assess the safety and efficacy of EXPAREL when administered via infiltration into the transversus abdominis plane (TAP) to prolonged postsurgical analgesia in men undergoing robot-assisted laparoscopic prostatectomy.

NCT ID: NCT00672594 Completed - Prostate Cancer Clinical Trials

Study of Sunitinib Malate in Patients With Newly Diagnosed Prostate Cancer Prior to Prostatectomy

Start date: July 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to look at blood and tissue samples for changes following the use of Sunitinib malate. Additionally, we would like to find out if the drug, Sunitinib malate, is safe and works in men with prostate cancer. Sunitinib malate , also known as Sutent, is approved by the U.S. Food and Drug Administration (FDA), for treatment of tumors of intestines and kidney but it is being tested in research studies for use in men with prostate cancer.

NCT ID: NCT00670345 Completed - Bleeding Clinical Trials

Tranexamic Acid in Urologic Surgery

TRANEX-URO
Start date: April 2008
Phase: Phase 4
Study type: Interventional

This prospective randomized double-blind placebo vs control study aims at verifying the efficacy of tranexamic acid administration in reducing perioperative bleeding in patients undergoing open radical prostatectomy. Two recent meta-analysis confirmed that tranexamic acid administration does not increase mortality, myocardial infarction, deep venous thrombosis, pulmonary embolism, stroke and renal failure. 200 patients undergoing open radical prostatectomy will be enrolled. Patients will receive a slow endovenous infusion of 500 mg of tranexamic acid before surgical incision, followed by 250 mg/h of tranexamic acid by continuous infusion. Patients belonging to the control group will receive the same volume of saline infusions.

NCT ID: NCT00288899 Completed - Surgery Clinical Trials

Benefits of 'Repeat Back' Protocols Within A Computer-Based Informed Consent Program

Start date: August 7, 2006
Phase: Phase 1
Study type: Interventional

This is a VA Merit Review Study involving 7 VA medical centers participating in a parallel group randomized trial comparing "repeat back" versus standard electronic consent for 4 common elective surgical procedures (total hip arthroplasty, carotid endarterectomy, laparoscopic cholecystectomy, and radical prostatectomy). Baseline covariates include health status (SF-12), reading ability (REALM), and demographics. Primary outcomes are patient comprehension of the informed consent, patient satisfaction with the informed consent and decision making processes, patient satisfaction with care, anxiety (STAI), and provider assessment of the "repeat back" process. In addition, we are electronically capturing data detailing time spent in each phase of the consent process including "repeat back".

NCT ID: NCT00177125 Completed - Prostatic Neoplasms Clinical Trials

Evaluating the Effect of the VCD on Erectile Function and Penile Length Post RRP

Start date: January 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to perform a randomized prospective study to evaluate whether the vacuum erection device facilitates an earlier return of erectile function post radical prostatectomy. A secondary measure will be to evaluate if the vacuum erection device can help prevent penile shortening.