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Pregnancy clinical trials

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NCT ID: NCT05929963 Enrolling by invitation - Pregnancy Clinical Trials

Observational Study of the Interaction Between Hepatitis C Virus Infection and Pregnancy

Start date: May 9, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about he effects of hepatitis C virus on pregnancy. The main question[s] it aims to answer are: Effect of hepatitis C virus on liver function in pregnant women Mother-to-child transmission rate in pregnant women with hepatitis C

NCT ID: NCT05872022 Enrolling by invitation - Obesity Clinical Trials

A Study to Evaluate Safety of Exposure to Wegovy During Pregnancy

Start date: July 5, 2023
Phase:
Study type: Observational

This is an observational, prospective Wegovy (semaglutide 2.4 milligram [mg]) Pregnancy Registry Study. The aim of this study is to compare the maternal, foetal, and infant outcomes of pregnant women who are exposed to Wegovy during pregnancy for the treatment of obesity or overweight with at least one weight-related comorbid condition with outcomes in an internal comparison cohort of pregnant women with obesity or overweight with at least one weight related comorbid condition at conception and who are not exposed to Wegovy or other glucagon-like peptide-1 receptor agonists (GLP-1 RAs) during pregnancy. Infant outcomes will be assessed throughout the infant's first year of life, with active data collection by the registry occurring at 4 and 12 months after delivery.

NCT ID: NCT05503927 Enrolling by invitation - Obesity Clinical Trials

A Study to Evaluate the Safety of Exposure to Wegovy During Pregnancy

Start date: January 2, 2023
Phase:
Study type: Observational

This is an observational, retrospective, cohort study using administrative insurance claims data. The aim of this non-interventional study (NIS) is to compare maternal, fetal and infant outcomes of women exposed to Wegovy during pregnancy to a reference population not exposed to Wegovy, so that participants and healthcare providers can make informed treatment decisions.

NCT ID: NCT05481983 Enrolling by invitation - Pregnancy Clinical Trials

Exercise Training on Gait Pattern in Pregnancy

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

The research will be conducted with healthy pregnant women who applied to the Ege University Gynecology and Obstetrics Department Polyclinic, and were referred to the Sports Medicine Department.The study will consist of two groups as the control group and the exercise group.Voluntary pregnant women who are not found to be inconvenient to do moderate-intensity exercise by the doctor will participate in the study.The study was planned as a randomized controlled and single-blind study.The participant's demographic information, obstetric assessment, physical activity level, fall history and pain assessment will be recorded.Foot plantar pressure, static and dynamic balance, center of pressure (COP), subtalar joint evaluation and gait evaluation will be measured by pedobarography at Ege University Orthopedics and Traumatology Department Gait Laboratory.The control group will be offered walking as recommended by ACOG for pregnant women.Clinical exercise training will be given to pregnant women in the study group by a specialist physiotherapist.

NCT ID: NCT05452174 Enrolling by invitation - Pregnancy Clinical Trials

Endeavor to Stop Nausea/Vomiting Associated With Pregnancy (E-SNAP)

ESNAP
Start date: June 13, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

The primary objective of this proposal is to conduct an early Phase 2 clinical trial to determine the acceptability, dosing, tolerability and safety of mirtazapine for severe nausea and vomiting of pregnancy (sNVP) that is not adequately responsive to current standard treatments. This plan mirrors clinical practice since commonly prescribed antiemetic/ antinauseant drugs will be tested for efficacy before treating with mirtazapine.

NCT ID: NCT05415371 Enrolling by invitation - Pregnancy Clinical Trials

Persistent Poverty Counties Pregnant Women With Medicaid

Start date: September 30, 2022
Phase: N/A
Study type: Interventional

Although many women initially quit smoking during pregnancy, most will return to smoking by the end of pregnancy or during the first 6 months postpartum. The proposed pilot project is designed to evaluate the feasibility and potential efficacy of offering small financial incentives for the completion of smoking cessation coaching and biochemically-verified smoking abstinence at follow-up among pregnant women with Medicaid insurance who contact the Oklahoma Tobacco Helpline (OTH). The study will enroll 100 pregnant women who will be randomly assigned to OTH care or OTH plus escalating incentives (OTH+I) for completing up to 5 coaching calls over the first 8 weeks after enrolling (prepartum) and for biochemically-verified smoking abstinence at 9 weeks post-enrollment (assessed remotely via smartphone). In addition, participants will be incentivized for completing a postpartum coaching call by 8 weeks postpartum. Feasibility outcomes for the incentives based intervention will focus on coaching call completion, rates of prepartum and postpartum follow-up, biochemically-verified smoking cessation, and perceptions of the intervention. Potential effectiveness will be evaluated by comparing biochemically-verified smoking abstinence rates in OTH+I relative to OTH alone at 12 weeks post-enrollment (prepartum) and 12 weeks postpartum.

NCT ID: NCT04942197 Enrolling by invitation - Pregnancy Clinical Trials

Fetal 3D Avatar Creation for Pregnant Women

Start date: June 2, 2021
Phase: N/A
Study type: Interventional

- Pregnant women can intuitively check the shape and development of the fetus through the 3D avatar that reflects the characteristics of the fetus. Through a survey on VR fetal experience content and 3D fetal avatar service, the satisfaction of pregnant women/guardians, the bond between the fetus and the mother, and Assess the degree of maternal anxiety. - Evaluate whether it can be helpful in prenatal monitoring of pregnant women through the use of maternity health management applications, and improve understanding of fetal growth and development.

NCT ID: NCT04885959 Enrolling by invitation - Healthy Clinical Trials

The Effects of Traditional Asian Diet on Gut Microbiome and Metabolome in Healthy Volunteers and Pregnancy on Subsequent Infant's Allergy Development

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The research aims to elucidate a specially-designed personalized diet based on Traditional Asian Diet and its efficacy in increasing the gut colonization of Prevotella sp. and butyrate levels in pregnant mothers and the benefits in reducing infant's food allergy development.

NCT ID: NCT04090307 Enrolling by invitation - Pregnancy Clinical Trials

Targeted Lifestyle Change Group Prenatal Care

TLC
Start date: November 26, 2019
Phase: N/A
Study type: Interventional

To conduct a randomized trial to determine the effect of Targeted Lifestyle Change Group Prenatal Care (TLC) on maternal and neonatal outcomes in women at high risk for developing gestational diabetes mellitus (GDM).

NCT ID: NCT03802734 Enrolling by invitation - Pregnancy Clinical Trials

Perinatal Effects of Mindfulness Phone App Use in Pregnancy (PaMPPr Study)

PaMPPr
Start date: August 15, 2019
Phase: N/A
Study type: Interventional

There is evidence to show that mindful meditation has a positive impact on health. To date, all the studies done to investigate the effect of mindfulness on pregnancy outcomes have been done through a traditional 8-10 weeks mindfulness classroom program with some home practice. This time-intensive classroom training may be expensive and not convenient for many busy pregnant women. This study will investigate the use of a smartphone app-based intervention to determine if it has the potential to make mindfulness training more accessible, acceptable, and convenient to a larger number of pregnant women. The use of an app as opposed to traditional structured classes may increase a woman's ability and willingness to practice mindfulness because the app can be used almost anywhere and at any time. This pilot study aims to explore the feasibility and acceptability of a smartphone mindfulness meditation application for pregnant women. As well, this study will compare the pregnancy outcomes of women who use the app to those women who do not use the app.