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Pregnancy clinical trials

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NCT ID: NCT06369272 Completed - Pregnancy Clinical Trials

Study to Assess Maternal and Infant Outcomes Following Exposure to SPIKEVAX During Pregnancy

Start date: March 1, 2023
Phase:
Study type: Observational

The primary objectives of this study are: In infants of women exposed to SPIKEVAX during pregnancy, to assess: - If exposure to SPIKEVAX during pregnancy is associated with an increased birth prevalence of major congenital malformations (MCMs). - If exposure to SPIKEVAX during pregnancy is associated with an increased birth prevalence of adverse neonatal and infant outcomes, specifically neonatal encephalopathy, small for gestational age, respiratory distress in the newborn, and incidence of hospitalization due to infections including coronavirus disease 2019 (COVID-19). - In women exposed to SPIKEVAX during pregnancy, to assess whether exposure to SPIKEVAX is associated with an increased prevalence of hypertensive disorders [e.g., pre-eclampsia, eclampsia, and gestational hypertension] gestational diabetes, and post-partum hemorrhage; and - To assess whether exposure to SPIKEVAX during pregnancy is associated with an increased incidence of stillbirth, preterm birth, and medically attended spontaneous abortion.

NCT ID: NCT06119971 Completed - Pregnancy Clinical Trials

Effect of Acupressure on the "Yin-Tang" and "Shen-Men" Points on Pre and Postoperative Anxiety in Elective Caesarean Section: a Prospective, Single-blind, Randomised, Controlled Trial

ACUCESAR
Start date: June 9, 2022
Phase: N/A
Study type: Interventional

Preoperative anxiety occurs commonly in elective caesarean section and is associated with increased perioperative morbidity. Some groups have used non-pharmacological techniques such as acupressure for its treatment since drugs cross the placenta.

NCT ID: NCT06076941 Completed - Pregnancy Clinical Trials

Effect Of Oral And Dental Health Education In Pregnant Women

Start date: April 15, 2017
Phase: N/A
Study type: Interventional

The study was conducted as a randomized controlled experimental study to determine the effect of the education given to pregnant women on their oral and dental health behaviors and knowledge levels.

NCT ID: NCT05946447 Completed - Pregnancy Clinical Trials

Intra- and Interrater Reliability of Quantitative Ultrasound Assessment of Gastric Content in Term Parturients Before Elective Caesarean Delivery

Start date: July 20, 2023
Phase: N/A
Study type: Interventional

The presence of solid food or fluid residue in the stomach is always a major concern when patients require medical procedures under sedation or general anesthesia, due to the high risk of pulmonary aspiration of the stomach contents. This is especially important in emergency procedures, when a fasting period could not be observed. Pulmonary aspiration of gastric content is a serious perioperative complication of obstetric anesthesia, and it is associated with morbidity and mortality. Information from a bedside ultrasound assessment of the stomach may be a very useful resource to decide whether it's safe to proceed, cancel or delay a surgical procedure. The ultrasound assessment of the stomach content has shown to be very feasible and practical in non-pregnant patients. However, it has not been determined whether the competence reached by anesthesiologists in non-pregnant subjects can be transferred to the obstetric population, especially in term pregnant patients where it could be difficult to identify the stomach because of the presence of the gravid uterus. Although quantitative assessment of the gastric antrum cross-sectional area in terms of intra- and interrater reliability has been evaluated in non-pregnant adults, it remains to be evaluated in pregnant patients. Furthermore, it has not been determined whether the performance of novice operators is comparable to expert operators in the gastric quantitative assessment. This study aims to determine whether trained anesthesiologists can reliably assess the stomach content of pregnant patients by ultrasound, evaluating the inter- and intra-rater reliability of quantitative gastric ultrasound in term pregnant patients comparing anesthesiologists of different level of expertise. The investigators hypothesize a substantial to almost perfect agreement in the intra- and interrater reliability of the antral cross-sectional area among raters in term pregnant patients scheduled for elective cesarean delivery.

NCT ID: NCT05928117 Completed - Pregnancy Clinical Trials

Training Given in the Line of Coping With Fear of Birth on Fear of Birth Birth Experience

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

Pregnancy and childbirth are a natural life event for women, as well as a process in which physical, biological and psychosocial changes are experienced. This process causes women to perceive childbirth as an unknown and unpredictable situation, resulting in the fear of childbirth. Due to the fear of childbirth, the daily routines, professional lives, social activities and relationships of pregnant women are significantly affected. This study was planned to evaluate the effect of mobile education given in line with the "Guide to Coping with Fear of Birth" on fear of birth, birth preference and maternal satisfaction at birth. Research; It will be carried out at the T. C. Ministry of Health Gaziantep Cengiz Gökçek Gynecology and Pediatrics Hospital. Data; The first one is 28-30th of pregnancy. week, the second is 36-38. It will meet in three meetings in total, the third of which will be within 12-24 hours postpartum. Data, Personal Information Form (Annex-1), Wijma Birth Expectation/Experience Scale (W-DEQ) Version A (Annex-2), Wijma Birth Expectation/Experience Scale Version B (Annex-3) and Birth Experience Scale ( Annex-4) and Postpartum Questionnaire (Annex-5). The obtained data will be analyzed with the SPSS 22.0 program. In this study, it is thought that the training given to women with a high level of birth fear can reduce their fear of childbirth and increase maternal satisfaction at birth.

NCT ID: NCT05892913 Completed - Pregnancy Clinical Trials

The Effect of Low-dose Atropine on Sympathetic Blockade in Spinal Cesarean Section Patients

Start date: July 19, 2023
Phase: Phase 4
Study type: Interventional

The most common side effect in cesarean section surgeries performed under spinal anesthesia is hypotension, which is seen in over 80% and can cause significant morbidity for the mother and fetus. This side effect results from the sympathetic blocking effect, which also causes bradycardia. A combined approach is supported in the prevention and treatment of hypotension, which recommends adequate fluid support, low-dose spinal anesthesia, and appropriate vasopressor (such as ephedrine, and phenylephrine) and, if bradycardia develops, the use of atropine as a parasympatholytic agent. In this study, the investigators planned to investigate the possible benefits of preemptive administration of atropine, the dose of which is calculated in proportion to the patient's weight, as soon as a 10% decrease in heart rate is detected, in order to balance the sympathetic blockade due to spinal anesthesia in cesarean section operations.

NCT ID: NCT05790967 Completed - Pregnancy Clinical Trials

The Effect of Sex Education on Sexuality of Pregnant Women

Start date: March 27, 2023
Phase: N/A
Study type: Interventional

Aim: In this study, it is aimed to determine the effect of sexual education given to pregnant women on attitudes towards sexuality and sexual response during pregnancy. The study will be carried out in two different groups. After the women are evaluated in terms of eligibility criteria for the research, the eligible pregnant women will be informed about the research and written informed consent will be obtained from those who accept. Random distribution of pregnant women to study groups will be made using the Block Randomization method. The following applications will be made to the groups. Education Group: Women in the experimental group will be given education on sexual life during pregnancy. Before the training, preliminary data will be collected and then the participants will be given two hours of individual and face-to-face training. At the end of the training, homework will be given to pregnant women to practice at home, including "sharing their sexual feelings and thoughts with their spouse, sharing problems and concerns about sexuality during pregnancy, and using alternative ways other than sexual intercourse. In addition, a "Sexual Life in Pregnancy Information Booklet" will be given, and they will be asked to read the information in the booklet and share it with their spouses. After 4 weeks, the data sheets will be applied again. Control Group: Patients in the control group of the study will not be subjected to any treatment other than the routine procedure. Data collection forms will be applied to the patients in the control group at the beginning of the study and after 4 weeks.

NCT ID: NCT05780112 Completed - Pregnancy Clinical Trials

The Effectiveness of The Breathing Exercise On The Nausea, Vomiting And Breathing Exercise In Pregnancy

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

Aim: This study aimed to investigate the effectiveness of the breathing exercise on pregnancy-related nausea and vomiting and the quality of life in the early pregnancy period. Background: Nausea and vomiting during pregnancy is a condition that can negatively affect the quality of life and the course of pregnancy in pregnant women. Nausea and vomiting during pregnancy with breathing exercises and can positively affect the quality of life women. Methods: This study is a single-blind randomised controlled trial. The sample consisted of 104 pregnant women. The Personal Information Form, the Nausea and Vomiting in Pregnancy Instrument and the 36-Item Short-Form Health Survey were used to collected the data.

NCT ID: NCT05736341 Completed - Pregnancy Clinical Trials

Comparison of Remimazolam and Midazolam for Preventing Intraoperative Nausea and Vomiting During Cesarean Section Under Spinal Anesthesia

Start date: May 17, 2023
Phase: N/A
Study type: Interventional

Spinal anesthesia is widely accepted as the anesthetic method of choice for Cesarean section. However, high-level blockage or hypotension induced by this technique may induce intraoperative nausea and vomiting (IONV), which is associated with patient discomfort and protrusion of abdominal viscera which may adversely affect patient safety. To prevent IONV, midazolam is frequently administered after delivery, but risk of hypotension and prolonged sedation due to its active metabolite also increases. On the other hand, remimazolam is known to have relatively shorter half-life and less likely induce hypotension when compared to midazolam, yet its effect on IONV has not been thoroughly evaluated. Hence, this study aimed to compare the effects of remimazolam and midazolam in preventing IONV in patients scheduled for elective Cesarean section.

NCT ID: NCT05681130 Completed - Pregnancy Clinical Trials

Effect of Depression, Anxiety and Stress Scores on Embryo Transfer Success

Start date: March 1, 2022
Phase:
Study type: Observational [Patient Registry]

Psychological status of couples attending to IVF programmes is important due to possible effect on final result. Observers aim to investigate the depression, anxiety and stress scores of couples before and after the procedure.