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The Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression

Postpartum Depression Clinical Trial

Official title:
A Pilot Study on the Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression

Clinical Trial Summary

Postpartum depression is a serious disorder that affects approximately 14% of women who have recently given birth. Postpartum depression is either an episode of major depressive disorder (only low periods) or bipolar disorder (periods of lows and highs). Untreated postpartum depression can negatively affect the mother, the infant and the family. Antidepressants are the most used treatments; however, for many women these drugs are not useful, resulting in a pressing need for effective treatments for postpartum depression. Lack of sleep is common after delivery and can trigger depression in some women. Quetiapine, a drug used for bipolar disorder, major depressive disorder and occasionally sleeplessness has not been well studied in postpartum depression. This study aims to find out how mothers tolerate the drug and whether it is effective for postpartum depression. Results of this study may help investigators carry out a larger study comparing quetiapine and placebo (a sugar pill) in postpartum depression.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04950868
Study type Interventional
Source Lawson Health Research Institute
Contact Verinder Sharma, MB
Phone 519-455-5110
Email vsharma@uwo.ca
Status Recruiting
Phase Phase 1
Start date March 18, 2022
Completion date December 31, 2024
View Details
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