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NCT02682004 Clinical Trial

Serotonin, Leptin and Adiponectin Level in Patients With Postpartum Depression: Controlled Study

Postpartum Depression Clinical Trial

Official title:
Serotonin, Leptin and Adiponectin Level in Patients With Postpartum Depression: Controlled Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02682004
Other study ID # 51
Secondary ID
Status Completed
Phase
First received
Last updated
Start date February 2016
Est. completion date May 2017

Study information
Verified date March 2022
Source Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

After vaginal delivery, all of the participants will evaluate by using Edinburg depression scale and venous blood sample will obtain. Postpartum depression will consider the result of scale 13 and above according to Turkhish translate. Then leptin, adiponectin and serotonin level will compare between depressed and nondepressed women.

Recruitment information / eligibility
Status Completed
Enrollment 400
Est. completion date May 2017
Est. primary completion date April 2017
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 20 Years to 40 Years
Eligibility Inclusion Criteria: - All women who gave birth Exclusion Criteria: - women with previously diagnosed depression and any psychiatric disorders - women with previously take antidepressan and antipshycothic - women giving birth to children with anomalies - women with undertake surgery for peripartum hemorrhage

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• leptin, serotonin and adiponectin level

• leptin,serotonin, adiponectin level

Locations
Country Name City State
Turkey Zeynep Kamil Maternity and Pediatric Research and Training Hospital Istanbul

Sponsors (1)
Lead Sponsor Collaborator
Zeynep Kamil Maternity and Pediatric Research and Training Hospital

Country where clinical trial is conducted

Turkey, 

References & Publications (3)

Hu Y, Dong X, Chen J. Adiponectin and depression: A meta-analysis. Biomed Rep. 2015 Jan;3(1):38-42. Epub 2014 Oct 16. — View Citation

Mansur RB, Rizzo LB, Santos CM, Asevedo E, Cunha GR, Noto MN, Pedrini M, Zeni M, Cordeiro Q, McIntyre RS, Brietzke E. Adipokines, metabolic dysfunction and illness course in bipolar disorder. J Psychiatr Res. 2016 Mar;74:63-9. doi: 10.1016/j.jpsychires.20 — View Citation

Skalkidou A, Sylvén SM, Papadopoulos FC, Olovsson M, Larsson A, Sundström-Poromaa I. Risk of postpartum depression in association with serum leptin and interleukin-6 levels at delivery: a nested case-control study within the UPPSAT cohort. Psychoneuroendo — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Blood level (ng/ml) ELISA 1 month
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