Studies of Mothers With Postnatal Depression

Status Completed

Clinical Trial Summary

This study investigates the effects of a single dose of oxytocin (OT) delivered via a nasal spray in women with and without traits of postnatal depression (PND).

Clinical Trial Description

A double-blind, placebo-controlled, case-controlled, randomised controlled-trial, within-subjects, cross-over design will be conducted. Participants will include mothers and their infant in the postnatal period. All participants will be screened for symptoms of low mood on the Edinburgh Postnatal Depression Scale (EPDS) and then assigned into 2 groups comprising probable PND cases and controls. All participants will take part in 3 conditions at Baseline (before nasal spray administration), Condition 1 (after first OT/Placebo administration) and Condition 2 (after second OT/Placebo administration), and will complete the same order of tasks. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04745494
Study type	Interventional
Source	University College, London
Contact
Status	Completed
Phase	N/A
Start date	May 12, 2017
Completion date	January 30, 2021

View Details

See also
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