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Post-operative Pain clinical trials

View clinical trials related to Post-operative Pain.

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NCT ID: NCT06082479 Completed - Inflammation Clinical Trials

The Effect of Intra Oral Cryotherapy in Patients With Symptomatic Apical Periodontitis

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

The participants were divided into two groups: Group I (cryotherapy) (n =10) after the completion of the mechanical preparation intra oral cryotherapy was applied. Group II (control) (n =10) received standard root canal treatment without the application of any type of cryotherapy.

NCT ID: NCT06065683 Completed - Post Operative Pain Clinical Trials

Acute Postoperative Pain Prevalence and Intensity in the First 72 Hours

Start date: September 1, 2022
Phase:
Study type: Observational

Postoperative pain is poorly studied in developing countries. Severe pain after surgery remains a major problem, occurring in 50% to 70% of the patients. Differences exist across countries. Despite numerous published studies, the degree of pain following many types of surgery in everyday clinical practice is unknown. To improve postoperative pain treatment and develop procedure-specific, optimized pain-treatment protocols, the prevalence and severity of postoperative pain must first be identified. This study aimed to determine the incidence and intensity of acute postoperative pain, to identify populations associated with a higher risk in order to guide resource allocation, and to investigate whether inexpensive analgesic modalities are currently utilized maximally.

NCT ID: NCT06062134 Completed - Post Operative Pain Clinical Trials

Pericapsular Nerve Group Block: An Imaging Study for Determination of the Spread of the Injectate Using 3-D CT Scan

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

Over the last 20 years, different interventional regional analgesia techniques have been proposed to treat pain after hip surgeries. The most commonly used techniques are the fascia iliaca and femoral nerve blocks, resulting in reduced pain scores, opioid-sparing effects, and opioid-related adverse effects. However, these interventional analgesia techniques result in a motor block and muscle weakness of the quadriceps muscle, impeding early ambulation and rehabilitation. Recently, the pericapsular nerve group (PENG) block has been proposed as an effective choice for analgesia after hip surgeries while sparing the motor function of the lower extremities. The aim of this technique is to inject local anesthetic to target the more distal sensory branches innervating the anterior aspect of the hip joint.

NCT ID: NCT06048744 Completed - Post Operative Pain Clinical Trials

Ultrasound Guided Erector Spinae Plane Block vs External Oblique Intercostal Plane Block for Nephrectomy

EOINBvsESB
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The patients will be randomly allocated into two equal groups using a computer program. Group A: will receive U S guided external oblique intercostal block after induction. Group B: Patients will receive US guided erector spine block after induction.

NCT ID: NCT06045078 Completed - Depression Clinical Trials

Aromatherapy in Total Knee Replacement

Start date: October 3, 2023
Phase: N/A
Study type: Interventional

The purpose of this pilot randomized controlled trial is to investigate the effects of aromatherapy on postoperative anxiety and pain in total knee replacement patients. The main questions to answer are: Does Lavender-Peppermint Aromatherapy reduce post operative anxiety in patients after primary total knee replacement when compared to placebo? Does Lavender-Peppermint Aromatherapy reduce post operative pain in patient after primary total knee replacement when compared to placebo? Does Lavender-Peppermint Aromatherapy reduce postoperative opioid consumption after primary total knee replacement when compared to placebo? Does Lavender-Peppermint Aromatherapy reduce postoperative nausea and vomiting after primary total knee replacement when compared to placebo? Participants will be assigned to one of the following groups at random: - Intervention: Aromatherapy with the lavender-peppermint scent - Control: Aromatherapy with the almond oil scent Participants will also be asked to complete pre- and post-operative questionnaires. Researchers will compare both groups (intervention vs control) to see if aromatherapy reduces post-operative anxiety, pain, opioid intake, and nausea/vomiting.

NCT ID: NCT06007066 Completed - Post-operative Pain Clinical Trials

HSK16149 for Perioperative Analgesia in Orthopedic Surgery

Start date: March 8, 2023
Phase: Phase 2
Study type: Interventional

This study will compare the effect and safety of HSK16149 with placebo on perioperative analgesia in orthopedic surgery, and explore the dosage of HSK16149 capsules for orthopedic analgesia during perioperative period.

NCT ID: NCT06003933 Completed - Post Operative Pain Clinical Trials

Inter-semispinal Plane Block and Cervical Spine Surgery

ISPB
Start date: March 3, 2023
Phase: N/A
Study type: Interventional

The inter-semispinal plane (ISP) block is a novel ultrasound-guided technique that involves local anesthetic injection into the fascial plane between the semispinalis cervicis and semispinalis capitis muscles with subsequent block of the dorsal rami of the cervical spinal nerves and hence can get adequate postoperative analgesia. The authors hypothesized that ISP block can reduce the postoperative analgesic consumption in patients undergoing posterior cervical spine surgeries. The aim of this study is to evaluate the analgesic efficacy of ISP block in patients undergoing posterior cervical spine surgery.

NCT ID: NCT05993975 Completed - Post Operative Pain Clinical Trials

Effects of Intrathecal Dexmedetomidine as an Adjuvant to Low Dose Hyperbaric 0.5% Bupivacaine

Start date: July 20, 2021
Phase: Phase 4
Study type: Interventional

Patients will be enrolled in one of the two groups using a computer-generated random number table: Group I will receive 1.5 ml of 0.5% hyperbaric bupivacaine (7.5 mg). Group II will receive 1.2 mL of 0.5% hyperbaric bupivacaine (6 mg) along with 0.3 mL (3 μg )of dexmedetomidine (total 1.5 mL).

NCT ID: NCT05983393 Completed - Pain Clinical Trials

Erector Spina Plane Block for Multilevel Major Spinal Surgery

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles. This study aims to examine the postoperative analgesic efficacy of ESP block in patients undergoing posterior spinal instrumentation

NCT ID: NCT05982392 Completed - Post Operative Pain Clinical Trials

Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain

Start date: March 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to compare in Tramadol, Naproxen sodium and Placebo in participants presenting with irreversible pulpitis in their mandibular posterior teeth. The main question[s] it aims to answer are: - Local anesthetic efficacy and . - Postoperative pain. Participants will receive premedication treatments 60 minutes prior to the local anesthesia administration. Researchers will compare Tramadol, Naproxen sodium and Placebo to evaluate their effects on Inferior alveolar nerve block efficacy and Postoperative pain.