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Post-operative Pain clinical trials

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NCT ID: NCT04540848 Withdrawn - Post Operative Pain Clinical Trials

Post Operative Pain Control for Distal Radius Surgery: Does Exparel Injected at the Surgery Site Improve Postoperative Pain Scores at 24 and 48 Hours ?

Start date: March 1, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to see if Exparel, used intraoperatively by injecting at the surgical site, followed by a Supraclavicular nerve block with bupivacaine in the recovery room, will provide better pain scores for patients at 24 and 48 hours post operatively than, 1)Bupivacaine Hydrochloride (HCL) injection at the surgical site, with a supraclavicular block in Post-anesthesia care unit(PACU), or 2)a supraclavicular block in PACU without any kind of injection at the surgical site.

NCT ID: NCT04360135 Withdrawn - Post Operative Pain Clinical Trials

Preemptive Acetaminophen for Postoperative Pain Control Following Minimally Invasive Hysterectomy

Start date: May 6, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

This study is investigating whether administration of acetaminophen the day before surgery improves post operative pain following minimally invasive hysterectomy. Patients will receive either acetaminophen or placebo to take twice per day the day prior to their scheduled surgery. The morning of surgery all participants will receive oral acetaminophen at least 30 minutes prior to surgery. The investigators will examine whether there is a difference in post operative pain between the two groups.

NCT ID: NCT03877549 Withdrawn - Post Operative Pain Clinical Trials

Dexamethasone Administered Via the Epidural Catheter as an Adjunct in Patients Undergoing Cesarean Delivery

Start date: May 24, 2019
Phase: Phase 4
Study type: Interventional

This study will evaluate the ability of dexamethasone to enhance labor epidurals when administered as an adjunct to local anesthetics via an epidural catheter. Patients undergoing elective cesarean sections will be randomized into three groups, each receiving the same combined spinal epidural (CSE). At surgical closure, Group 1 will receive 10cc bupivacaine 0.0625%, Group 2 will receive 10cc bupivacaine 0.0625% +4mg dexamethasone, and Group 3 will receive 10cc bupivacaine 0.0625% + 8mg dexamethasone (4mg). VAS, sedation, nausea, and satisfaction scoring will be measured on patient follow-up to compare the outcomes of the different treatment groups.

NCT ID: NCT03484650 Withdrawn - Post Operative Pain Clinical Trials

Systemic Lidocaine Infusion for Pain Control in Ventral Hernia

Start date: January 14, 2020
Phase: Phase 3
Study type: Interventional

Ventral hernia repair leads to more than expected pain. This is thought to be secondary to nerve pain at the lateral transfixion sutures. Systemic lidocaine given pre-op has in other situations decreased neurogenic pain. This study will examine its effects on pain experienced after ventral hernia repair.

NCT ID: NCT03359798 Withdrawn - Opioid Use Clinical Trials

RCT of Counseling Intervention on Post-op Opiate Use

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial to investigate the effect of a simple counseling intervention on post-operative narcotic requirements, with the hypothesis that women receiving this intervention will use fewer narcotics for pain management following cesarean section.

NCT ID: NCT03197311 Withdrawn - Post Operative Pain Clinical Trials

A Mobile Application for Post-op Analgesic Consumption

Start date: October 2019
Phase: N/A
Study type: Interventional

Surgical extraction of third molars is one of the most common outpatient procedures performed by oral surgeons. The prescription of postoperative narcotic and NSAID analgesics is the standard of care practice to relieve symptoms of pain, swelling, and trismus after these procedures. The majority of these patients do not return for follow up unless they experience a problem. There is limited data on whether the patients use the narcotics as directed and what is their practice of disposal of the remaining medications that were not consumed. In this research the effectiveness of postop analgesic consumption, analgesic disposal practice, pain control, and patient satisfaction will be compared between patients who are randomized to the intervention group who will use a developed mobile application and a control group who will not use the mobile app.

NCT ID: NCT02822196 Withdrawn - Breast Cancer Clinical Trials

Serratus Anterior Muscle Plane Block vsThoracic Paravertebral Block For Unilateral Mastectomies

Start date: December 2018
Phase: Phase 4
Study type: Interventional

HYPOTHESIS Serratus Anterior Muscle Plane Block (SPB) is as effective as thoracic paravertebral block (PVB) for acute pain control after unilateral mastectomies. SPECIFIC AIMS Primary aim: To evaluate the efficacy of SPB block vs thoracic PVB for acute pain control in patients undergoing unilateral mastectomy Secondary aim To compare the onset and duration of block and dermatomes blocked in both groups To compare the need of post-operative rescue analgesia in both groups. To compare the development of chronic incisional pain in both groups Functional outcome with respect to daily activities.

NCT ID: NCT02752230 Withdrawn - Post Operative Pain Clinical Trials

Comparison of Exparel to Marcaine in Post-Surgical Analgesia in Bariatrics

Start date: November 29, 2016
Phase: Phase 4
Study type: Interventional

This study is designed to evaluate the use of bupivacaine liposome 1.3% compared bupivacaine 0.5% in pain control in post-operative laparoscopic bariatric surgery patient The purpose of this study is to evaluate two local anesthetics and determine if there is an advantage of administering one medication compared over the other. The intent is show that one local anesthetic.allows for improved pain control as per the pain scale ratings of the test subjects.

NCT ID: NCT02737124 Withdrawn - Post Operative Pain Clinical Trials

Acetaminophen Randomized Controlled Trial

Start date: February 16, 2017
Phase: Phase 3
Study type: Interventional

Patients that are to undergo isolated meniscectomy will be randomized to 2 cohorts: one will take the FDA recommended dose of acetominophen (1000mg) 24hrs before surgery, one will be given a similarly looking placebo pill. A multitude of post-op variables will be included, mainly pain scores and morphine equivalent doses at different time points.

NCT ID: NCT02438852 Withdrawn - Post-operative Pain Clinical Trials

Continuous Infusion of Ropivacaine Hydrochloride in Reducing Pain After Surgery in Patients With Bladder Cancer

Start date: February 25, 2019
Phase: Phase 3
Study type: Interventional

This randomized phase IV trial studies how well the continuous infusion of ropivacaine hydrochloride works in reducing pain after surgery in patients with bladder cancer. Ropivacaine hydrochloride is an anesthetic drug used to decrease pain by numbing an area of the body without putting the patient to sleep. Continuous infusion of ropivacaine hydrochloride may reduce pain and improve the quality of life for patients after bladder surgery.