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Polycystic Ovary Syndrome clinical trials

View clinical trials related to Polycystic Ovary Syndrome.

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NCT ID: NCT05348265 Completed - Clinical trials for Polycystic Ovary Syndrome

High Intensity Interval Training in PCOS

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Study objective is to determine the effect of High intensity interval training on psychological wellbeing, Anthropometrics and Quality of life in females with Polycystic Ovarian Syndrome

NCT ID: NCT05344547 Completed - Cardiac Disease Clinical Trials

Women With Polycystic Ovary Syndrome Are at High Risk for Cardiac Insults

Start date: March 21, 2020
Phase:
Study type: Observational

Objectives: Evaluation of the cardiovascular (CV) risk in a sample of CV asymptomatic infertile women with polycystic ovary syndrome (PCOS). Patients & Methods: 100 infertile PCOS women older than 30 years (PCOS group) and 50 fertile non-PCOS women (Non-PCOS group) underwent gynecological and laboratory diagnosis and then underwent a diagnostic protocol consisting of determination of body mass index (BMI), Homeostasis model assessment of insulin resistance (HOMA-IR) scoring and cardiologic evaluation using echocardiography, estimation of carotid artery intima-media thickness (CIMT), coronary artery calcium (CAC) score using multi-slice non-contrast cardiac CT and cardiac risk ratio (CRR). Study outcomes included the incidence of abnormal cardiac risk parameters and the determination of the best minimally invasive modality to be used as a screening test for these women.

NCT ID: NCT05340634 Completed - Clinical trials for Polycystic Ovary Syndrome

Evaluation of Metionac for the Modulation of Metabolic and Endocrine Parameters in Patients With PCOS.

Start date: April 20, 2020
Phase: Phase 4
Study type: Interventional

Evaluate the efficacy of the combination of antioxidants ALA, NAC, Vit. B6 and SAMe as a dietary supplement, in the improvement of metabolic and endocrine parameters and clinical manifestations of PCOS.

NCT ID: NCT05320289 Completed - Clinical trials for Polycystic Ovary Syndrome

Feasibility Study of the AblaCare System in Transvaginal Ablation of Ovarian Tissue Under ULTRAsound Visualization in Women With Infertility Due to Polycystic Ovary Syndrome

ULTRA-US
Start date: May 12, 2022
Phase: N/A
Study type: Interventional

The objective of the study is to provide preliminary evidence for the safety and effectiveness of the AblaCare System in transvaginal ablation of ovarian tissue under ultrasound visualization in women with infertility due to polycystic ovary syndrome (PCOS) who have not responded to first-line ovulation induction treatment or are contraindicated for or decline such treatment.

NCT ID: NCT05311059 Completed - Clinical trials for Polycystic Ovary Syndrome

Impact of Laparoscopic Ovarian Drilling on Ovarian Reserve in Patients With Anovulatory Polycystic Ovarian Syndrome

Start date: May 30, 2018
Phase: N/A
Study type: Interventional

Pneumoperitoneum is done by insertion of the verress needle at the inferior edge of the umbilicus putting into consideration the following tests: 1. Needle test: Verress needle patency check. 2. Hissing phenomenon: Needle introduced by open valve mechanism. 3. Aspiration test: Placing a drop of water on the opening of the needle and examine its disappearance into the abdomen. 4. Volume test: Changes occurred in the intra abdominal pressure during gas insufflations. Intra abdominal pressure 12-16 mmHg usually suitable for this pelvic surgery. Introduction of the laparoscopic instruments all in its place - Laparoscopic telescope : From the inferior edge of umbilicus through trocar and sleeve which inserted by corkscrew technique then removed to allow the telescope insertion which connected to light source , camera head and color monitor. - 2nd and 3rd punctures were done allowing another two graspers to be inserted usually at a point represent outer 1/3 of the lateral abdominal wall in an imaginary line from umbilicus to iliac bone Puncturing technique : Fixation of one ovary away from intestine by grasping the ovarian ligament with the traumatic grasper which allow good exposure of the ovary and allow drilling . Drilling needle was introduced and connected by monopolar current, held against ovarian surface for 4 seconds using a power of 40 watt, 4 puncture was done in each ovary with putting into consideration that the puncture must be not superficial and it must go deep through the main substance of the ovary. Cooling of the ovary by lactated ringer's solution, finally removal of all instruments under vision after exclusion of any complication .

NCT ID: NCT05246306 Completed - Clinical trials for Polycystic Ovary Syndrome

Aerobic Capacity and Physical Fitness Level of Adolescents With PCOS

Start date: September 22, 2021
Phase:
Study type: Observational

Polycystic Ovary Syndrome (PCOS) is associated with hyperandrogenism, hyperinsulinemia and insulin resistance starting in the perimenarchal period. Insulin resistance also increases the risk of developing glucose intolerance, type 2 diabetes, hypertension, dyslipidemia and cardiovascular disorders. Studies on adult women with PCOS show that their aerobic capacity is affected. Therefore, in this study; it was aimed to compare the physical and cardiovascular fitness levels of adolescent PCOS patients with healthy adolescents.

NCT ID: NCT05233514 Completed - Clinical trials for Polycystic Ovary Syndrome

Effect of Aerobic Exercise on Polycystic Ovary Syndrome

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

The development of Polycystic Ovary Syndrome has been linked to chronic low-grade inflammation (PCOS). In this context, the current study looked into the effects of aerobic exercise on IL6, TNF, and C-reactive protein (CRP) in PCOS women. This was a randomized clinical trial including 40 females diagnosed with PCOS who were between the ages of 25 and 35. The participants were divided into two groups, each with an equal number of individuals: aerobic exercise (AEM) and Metformin (M). At baseline and after 12 weeks of intervention, participants' levels of IL6, TNF, and CRP were measured.

NCT ID: NCT05231980 Completed - Clinical trials for Polycystic Ovary Syndrome

Efficacy of Pentoxifylline and Alpha Lipoic Acid in PCOS Resistant to Clomiphene Citrate

Start date: June 5, 2022
Phase: Phase 2
Study type: Interventional

This study evaluate the addition of PTX and ALA to clomiphene citrate in the treatment of polycystic ovary.

NCT ID: NCT05215223 Completed - Insulin Resistance Clinical Trials

Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome

WBV
Start date: March 30, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of whole body vibration on insulin resistance in females with polycystic ovarian syndrome

NCT ID: NCT05189873 Completed - Clinical trials for Polycystic Ovary Syndrome

GnRH Agonist Plus Hormone Replacement Therapy vs Hormone Replacement Therapy on IVF Outcomes

Start date: June 10, 2021
Phase: Phase 3
Study type: Interventional

The study is conducted at Arash Women's Hospital on all women undergoing the frozen embryo transfer cycle. Patients who signed informed consent will be randomly divided into two groups. The first group will receive GnRH agonist plus hormone replacement therapy for endometrial preparation. Group 2 will receive hormone replacement therapy. The random allocation and final outcome of the study will be assessed by a person who is unaware of the study process. Also, the statistician will be unaware of the study process