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Efficacy of Pentoxifylline and Alpha Lipoic Acid in PCOS Resistant to Clomiphene Citrate

Polycystic Ovary Syndrome Clinical Trial

Official title:
Evaluation of the Effect of Pentoxifylline and α-Lipoic Acid as Adjunctive Therapy in Patients With Clomiphene Citrate Resistant Polycystic Ovary Syndrome

Clinical Trial Summary

This study evaluate the addition of PTX and ALA to clomiphene citrate in the treatment of polycystic ovary.

Clinical Trial Description

Clomiphene, PTX and ALA each used in treatment of pco but they do so by different mechanisms. Clomifene is in the selective estrogen receptor modulator (SERM) family of medication. It works by causing the release of gonadotropin-releasing hormone by the hypothalamus, and subsequently gonadotropin from the anterior pituitary. PTX and ALA are used in treatment of pco due its anti-oxidant effect. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05231980
Study type Interventional
Source Ain Shams University
Contact
Status Completed
Phase Phase 2
Start date June 5, 2022
Completion date June 7, 2023
View Details
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