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Peripheral Arterial Disease clinical trials

View clinical trials related to Peripheral Arterial Disease.

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NCT ID: NCT03378024 Enrolling by invitation - Diabetes Clinical Trials

Evaluate the Correlation of NIRS, ABI, Exercise, baPWV and Albuminuria With Peripheral Artery Occlusion Disease (PAD) and Other Atherosclerosis Outcomes

Start date: December 1, 2016
Phase: N/A
Study type: Observational

By utilizing Near infrared spectroscopy (NIRS), the local blood flow, tissue oxygenation (StO2), and recovery time of ischemic leg; can be determined. It is reasonable to standardize an easy, simple and safe Active Pedal Plantarflexion (APP) exercise test working load which can achieve the lowest StO2 and other parameters in ischemic leg through observation of NIRS. After standardized of an effective APP test, a determination of a new cutoff value of resting ABI in diagnosing PAD can probably be searched. Analysing the correlation of baPWV with ABI, atherosclerosis risk factors and parameters with atherosclerosis outcome. Observation the Sequential changes of baPWV, ABI and microalbuminuria after managing the atherosclerosis risks, and analyze their influence on the outcome of PAD, coronary artery disease(CAD) and cerebral vascular disease(CVA) outcomes.

NCT ID: NCT02864654 Enrolling by invitation - Clinical trials for Peripheral Arterial Disease

Effectiveness and Safety of Adipose-Derived Regenerative Cells for the Treatment of Critical Lower Limb Ischemia

Start date: July 2016
Phase: Phase 1/Phase 2
Study type: Interventional

Adipose-derived regenerative cells (ADRC) will be extracted from lipoaspirate by enzymatic digestion. 10 mL of autologous ADRC suspension injected intramuscularly, close to the site of muscle injury. All patients will receive cell therapy. This is a single arm study with no control.

NCT ID: NCT02762864 Enrolling by invitation - Clinical trials for Peripheral Artery Disease

Post-operative Treatment of Diabetic Peripheral Arterial Disease Guided by Platelet Reactivity Unit

Start date: May 2016
Phase: N/A
Study type: Interventional

To compare the effect of PRU(platelet (P2Y12) reaction units)-guided treatment on the change in 1. time of initial leg pain and time of termination of exercise test by pain, evaluated on the graded stationary bicycle test, 2. the lower limb perfusion by using MRI blood oxygenation-level dependent (BOLD) and dynamic contrast enhancement sequences and measures the extracellular volume fraction (ECV) as an indicator of fibrosis severity in calf muscles, from one to 52 weeks post-revascularization in patients with peripheral artery disease who have undergone endovascular revascularization -/+ bypass surgery for moderate to severe claudication or ischemic rest pain.

NCT ID: NCT02581904 Enrolling by invitation - Clinical trials for Peripheral Arterial Disease

Prevena Vascular Groin Wound Study

Start date: January 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if the application of a negative pressure dressing intraoperatively (Prevena; KCI, Inc) to vascular groin incisions decreases the wound complication rate in high risk patients.

NCT ID: NCT01983215 Enrolling by invitation - Obesity Clinical Trials

Effects of Prevena Therapy on Obese and or Diabetic Patients With Surgical Groin Sites

Start date: April 2013
Phase: N/A
Study type: Interventional

The purpose of the study is to determine the effects of Prevena therapy on decreasing groin surgical site infections in patients who are obese and /or diabetic having vascular surgery.

NCT ID: NCT01932671 Enrolling by invitation - Stroke Clinical Trials

The SMART-ORACLE Study

SMART-ORACLE
Start date: August 2012
Phase: N/A
Study type: Observational

After having had a first cardiovascular event, there is a considerable risk of developing a subsequent event. Only recently, a risk prediction model was developed for this group of patients. Imaging techniques such as the coronary artery calcium score and contrast-enhanced computed tomography (CT) of the coronary and carotid arteries could be able to add improve this model. Imaging may further improve the prediction of future manifestations of arterial disease and personalize disease monitoring and treatment.

NCT ID: NCT01759225 Enrolling by invitation - Atrial Fibrillation Clinical Trials

Registry of Cardiovascular Disease Patients

CVD Registry
Start date: January 1998
Phase: N/A
Study type: Observational [Patient Registry]

A computerized registry of cardiovascular disease patients in a large health maintenance organization in Israel. The registry is aimed to be used by health professionals to identify cardiovascular disease patients and to follow the courses of their illnesses and risk factors.