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Periodontal Diseases clinical trials

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NCT ID: NCT05646498 Active, not recruiting - Clinical trials for Partial Edentulism Class 2 Due to Periodontal Disease

Management of Distally Extension Maxillary Atrophied Ridge With Two Different Minimal Invasive Treatment Modalities

Start date: March 21, 2021
Phase: N/A
Study type: Interventional

This study will compare clinical and radio graphic outcomes of two minimally invasive different treatment modalities for atrophied unilateral distal extension maxillary ridges these modalities include 1. Medially placed implant and Implant retained distal extension removable partial denture 2. Sinus lift and long implant to support fixed screw-retained prosthesis

NCT ID: NCT05639582 Completed - Clinical trials for Periodontal Diseases

Fractal Analysis Method in Periodontal Disease

Start date: November 5, 2020
Phase: N/A
Study type: Interventional

In this study, the effects of periodontal disease on alveolar bone were investigated using fractal analysis method.

NCT ID: NCT05636683 Enrolling by invitation - Clinical trials for Periodontal Diseases

Bone Remodeling and Non-surgical Periodontal Therapy

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Previous studied have investigated the pathophysiological role and expression of Cathepsin K (Ctsk) , receptor activator of the NF-κB ligand (RANKL) and periostin in active periodontitis and peri-implantitis lesions. However, the potential influence of non-surgical periodontal therapy including scaling and root planning on the bone remodeling markers level over different trial times have not well determined. Thus, the current research is conducted to address this influence. Thus, the research question will be: In patients with periodontitis, does the level of bone remodeling markers altered after successful NSPT during different healing time periods?

NCT ID: NCT05631600 Completed - Clinical trials for Periodontal Diseases

Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study

Start date: September 11, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this split-mouth clinical trial is to evaluate the effects of Manuka honey applied into periodontal pockets after initial periodontal therapy (NSPT) in the treatment of stage 3 periodontitis. The main question it aims to answer is: • does the adjunct of Manuka honey improve the outcome of the non-surgical periodontal treatment. The intervention in this study was conducted in a split-mouth design, meaning that after completing the NSPT for each subject, Manuka honey was administered as an adjunct to the periodontal treatment in two randomly selected quadrants of the oral cavity around the teeth with a specially designed cannula. This was followed by oral hygiene instructions and training. The home-performed oral hygiene procedures were focused on interdental cleaning using dental floss and toothbrushing with regular fluoride-containing toothpaste. The subjects were also instructed not to use any form of oral antiseptic (e.g., chlorhexidine) or antibiotic during the follow-up period.

NCT ID: NCT05631197 Completed - Dental Caries Clinical Trials

Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis

Start date: March 2, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to compare the incidence of dental caries and the level of demineralization in pediatric patients with asthma and/or allergic rhinitis. Patients will conduct professional oral hygiene at the baseline. The following clinical indexes will be assessed: BEWE Index, Plaque Index, Bleeding Score, Schiff Air Index. Then, patients will be randomly divided into two groups: - Trial group: domiciliary use of Biorepair Total Protection Plus + desensitizing enamel-repair shock treatment twice a day - Control group: domiciliary use of Elmex Caries Protection twice a day The clinical indexes will be assessed again after 1 month (T1), after 3 (T2) and 6 months (T3).

NCT ID: NCT05622019 Completed - Healthy Clinical Trials

Periodontitis, Sleep Quality and Fatigue

Start date: March 1, 2022
Phase:
Study type: Observational

The goal of this observational study is to investigate the association of stage-grade of periodontitis with sleep quality and fatigue and the effect of periodontitis on QoL (Quality of life) in individuals with periodontitis and gingivally healthy individuals. The main questions it aims to answer are: 1. Have poor sleep quality, inadequate sleep and fatigue got an effect on periodontal status? 2. Has periodontal status got an effect on sleep quality and fatigue? 3. What is the effect of periodontal status on quality of life? Routine clinical and radiographic periodontal examinations of the participants were performed. Groups were designed according to periodontal status and periodontitis-stages of participants. Group 1- Healthy; Group 2- Stage I periodontitis; Group 3- Stage II periodontitis; Group 4- Stage III periodontitis; Group 5- Stage IV periodontitis. The participants were only asked to fill out the questionnaires (socio-demographic survey, tooth cleaning habit survey, The Pittsburgh Sleep Quality Index(PSQI), The Jenkins Sleep Scale(JSS), Multidimensional Assessment of Fatigue scale (MAF) and Oral Health Impact Profile-14 (OHIP-14)) included in the study and were informed about them. Then, if necessary, the participants' routine periodontal treatments were performed. In line with the findings of the study; 1. Sleep quality was found higher in gingival healthy individuals. 3. The severity of periodontitis increases, the sleep duration becomes shorter, 4. It has been observed that the sleep quality in terms of gender is lower in female individuals compared to male individuals.

NCT ID: NCT05604703 Completed - Clinical trials for Periodontal Diseases

Comparison of Two Different Periodontal Classification

Start date: April 1, 2021
Phase:
Study type: Observational

Due to some deficiencies in the classification defined by Armitage in 1999, a new periodontal classification was published in 2018. New periodontitis A staging and grading system was used for classification. Staging depends largely on the severity of the disease, while grading is based on the rate of disease progression to the past. It provides additional information on a risk-based analysis and assessment of risk.The aim of this study is to reveal the differences between the old periodontal classification and the new periodontal disease classification published in 2018. Periodontitis in the literature review. The two classifications were compared in patients. However, a study on gingival recession not done. Anamnesis, routine periodontal indices, routine radiographs of 300 patients, first of all According to the 1999 Periodontal Disease Classification, after it will be classified according to the New Periodontal Disease Classification developed in 2018. Thus, two different Periodontal Disease Classifications, old and new, comparison will be made.

NCT ID: NCT05602545 Completed - Clinical trials for Periodontal Diseases

Periodontal Status in Fermented Food and Food Consumption

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

Lack of certain nutrients and foods may negatively affect oral health. Therefore, nutrition plays an important role in maintaining oral health. This study aimed to evaluate and compare the nutrient intakes, consumption of food groups and some fermented foods of individuals with periodontal disease and health. Ninety-three patients who applied to Periodontology Clinic were divided into three groups: periodontal health, gingivitis and periodontitis. In addition, plaque, gingival indices, bleeding on probing, periodontal pocket depth, and clinical attachment level were evaluated. To determine individuals' daily energy and nutrient intakes and the consumption amounts of food groups, food consumption records were kept by the nutritionist for three consecutive days, with one of them was weekend, using the 24-hour recall method. Data on individuals' frequency and amount of consumption of some fermented products were recorded, considering the foods available in our culture and the market.

NCT ID: NCT05590780 Completed - Clinical trials for Cardiovascular Diseases

Analysis of Cell-free DNA (cfDNA) During Periodontitis

Start date: November 1, 2019
Phase:
Study type: Observational

The purpose of this study was to examine the association between circulating cfDNA concentration and CVD risk in patients with periodontitis, CVD, and periodontitis plus CVD. In addition, the secondary objective was to identify, among other confounders, the impact of periodontitis and cardiovascular disease as potential significant predictors of circulating cfDNA levels in the enrolled population.

NCT ID: NCT05588544 Completed - Clinical trials for Periodontal Diseases

YSGG Application in Periodontal Treatment

Start date: May 26, 2020
Phase: N/A
Study type: Interventional

Adjunctive use of Er,Cr:YSGG (erbium-chromium-yttrium-scandium-gallium-garnet) laser in combination with conventional, mechanical periodontal treatment may benefit in complete decontamination of the periodontal pocket leading to improved early healing and better long term clinical result. Radial firing periodontal tip (RFPT) offered by the Er,Cr:YSGG system is devised to let irradiation primarily in radial pattern (85%) with lesser portion in straight manner (15%), meaning laser beams are effectively emitted to affected root surface and inner epithelium of periodontal pocket with simple tip management. Therefore, using Er,Cr:YSGG laser with RFPT could be the best option for periodontal laser therapy. The aim of this study is to investigate adjunctive treatment effect using Er,Cr:YSGG laser and RFPT in moderate to severe periodontitis patients. Study subjects are randomly allocated to either 'scaling and root planing (SRP) only' or 'SRP + laser therapy' group. Periodontal parameters including probing pocket depth (PPD), clinical attachment level (CAL), modified gingival index (MGI), and plaque index (PI) are recorded at baseline and 8 weeks after treatment. Gingival crevicular fluid (GCF) samples are obtained using paper strips at baseline, 1w, 2w, 4w, and 8w post op. to determine laser-induced effect in early wound healing. Cytokine levels are evaluated from the GCF samples taken.