Pediatric Obesity Clinical Trial
Official title:
Translating Habituation Research to Interventions for Pediatric Obesity
The purpose of this center grant is to translate basic behavioral science on habituation theory into clinical intervention using a vertical hierarchical approach from laboratory studies to field studies to the clinical intervention to improve weight loss outcomes in pediatric obesity treatment.
Habituation is one factor that may be related to excess energy intake. Research has shown that the rate of habituation is inversely related to the amount of food consumed and slower habituation may be a factor that is relevant to obesity, as overweight youth and adults habituate slower and consume more energy than their peers. Habituation is a basic form of learning that is observed in many response systems. We believe that habituation is an important process that mediates food regulation during a meal and across meals. However, there has been no research in children that translates basic research on habituation to food into clinical interventions for pediatric obesity. In the first phase, we will implement a series of laboratory studies to assess the effects of stimulus specificity and variety and the simultaneous reduction of variety for high energy density foods on short (within meal) and long-term (across meal) habituation. The second phase is designed to implement a series of field studies that will extend basic research from the first phase as well as define the optimal interval for reducing variety to facilitate long-term habituation to high energy density foods in the natural environment. The third phase is designed to develop and pilot test a family-based behavioral intervention for children that incorporates findings from phase2 into a clinical intervention. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT03994419 -
PErioperAtive CHildhood ObesitY
|
||
| Recruiting |
NCT06111040 -
Nurturing Needs Study: Parenting Food Motivated Children
|
N/A | |
| Completed |
NCT03036696 -
The BEACH Interview Study- Pregnant and Breastfeeding Mothers
|
||
| Completed |
NCT02959034 -
Pediatric Metabolism and Microbiome Repository
|
||
| Not yet recruiting |
NCT02484612 -
Exercise Intensity and Appetite in Adolescents
|
N/A | |
| Completed |
NCT02545764 -
Training Induced Reduction of Lower-limb Joint Loads During Locomotion in Obese Children
|
N/A | |
| Recruiting |
NCT02426346 -
A Scalable Weight Control Intervention for Adolescents
|
Phase 2 | |
| Completed |
NCT01989065 -
Healthy Lifestyles Program for You (HLP4U): Augmenting Childhood Obesity Treatment.
|
N/A | |
| Completed |
NCT02160847 -
Development of the DRIVE Curriculum to Address Childhood Obesity Risk Factors
|
N/A | |
| Completed |
NCT02343588 -
A National School-based Health Lifestyles Interventions Among Chinese Children and Adolescents Against Obesity
|
N/A | |
| Completed |
NCT01908153 -
Taste Reward Processing in Pediatric Obesity
|
||
| Completed |
NCT02375490 -
Healthy Start to Increase Physical Activity and Improve Healthy Eating in Early Childcare Centres
|
N/A | |
| Completed |
NCT02074332 -
Study on Obesity Intervention With Physical Exercise Among Students in Changping District, Beijing
|
N/A | |
| Completed |
NCT02086851 -
Study of a Structured Parent Intervention on Adolescent Weight Loss Modification Program.
|
N/A | |
| Terminated |
NCT00846521 -
Study of Post-meal Blood Sugar Peaks in Association With Vascular Disease in Childhood Obesity
|
Phase 4 | |
| Completed |
NCT01146314 -
A Family Based Intervention to Reduce the Risk of Type 2 Diabetes in Children
|
N/A | |
| Completed |
NCT04164277 -
FirstStep2Health Intervention
|
N/A | |
| Withdrawn |
NCT04600648 -
Sweet Taste Responsiveness in Relation to Insulin, Leptin and Adiposity Among Obese Treatment Seeking Children
|
N/A | |
| Completed |
NCT04395430 -
A Novel School-clinic-community Online Model of Child Obesity Treatment in Singapore During COVID-19
|
N/A | |
| Completed |
NCT03139877 -
Pediatric Obesity Observational Prospective Trial
|