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Parkinson Disease clinical trials

View clinical trials related to Parkinson Disease.

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NCT ID: NCT06328296 Not yet recruiting - Parkinson Disease Clinical Trials

Impact of Myofascial Release on Dysphagia in Parkinson's Disease Patients

Start date: April 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to explore Clinical Effect of Myofascial Release Therapy in Dysphagic Parkinson's Patients. The main question it aims to answer is: • Can Myofascial Release Therapy improve swallowing function in Parkinson's Patients? Patients will be randomly allocated into the control group or the experimental group, all under rehabilitation treatment, the experimental group will be given Myofascial Release Therapy. The study lasts 21 days for each patient. Researchers will compare the Functional Oral Intake Scale, Penetration-Aspiration Scale, Swallowing Quality of Life to see if the Myofascial Release Therapy can help improve the situation.

NCT ID: NCT06328218 Not yet recruiting - Parkinson Disease Clinical Trials

The Effect of Simple Gymnastics Training for Parkinson's Patients in the Community

Start date: March 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to explore the impact of Simple Gymnastics Training on Limb motor function and mental health in Parkinson's Patients in the Community (≥60 year old) with swallowing disorders. It primarily aims to address two key aspects: 1) the prevalence of Parkinson's Diseases among community-dwelling elderly individuals, and 2) the effects of Simple Gymnastics Training on Limb motor function and mental health in community-dwelling Parkinson's Patients. All patients are required to undergo a continuous three-week (21 days) Simple Gymnastics Training, with weekends off and training conducted only on weekdays. The training will be conducted two sessions per day, lasting 30 minutes each.

NCT ID: NCT06324422 Not yet recruiting - Parkinson's Disease Clinical Trials

Exercise as Treatment of Fatigue in Parkinson´s Disease

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The primary goal of this study is to test whether 12 weeks of high-intensity aerobic exercise can treat fatigue in Parkinsons disease (PD). The study will be a randomized multi-site controlled trial with follow up. Clinically fatigued persons with PD will be allocated to either 12 weeks of high-intensity aerobic exercise or to a waitlist control group receiving high-intensity resistance exercise after 24 weeks of habitual lifestyle (control period). It is hypothesized that persons with PD receiving 12 weeks of high-intensity aerobic exercise will show superior effects on perceived fatigue (i.e., clinical relevant reductions) when compared to the PD control group (primary hypothesis), and that these effects are sustained after 12-weeks of follow up (secondary hypothesis).

NCT ID: NCT06319625 Not yet recruiting - Parkinson Disease Clinical Trials

Effectiveness of Stellate Ganglion Block in Patients Diagnosed With Parkinson's Disease

Start date: March 2024
Phase: N/A
Study type: Interventional

The goal of this or clinical trial is to explore efficacy of stellate ganglion block on dysphagia and activities of daily living in patients with Parkinson's disease. The main question it aims to answer are: • Can stellate ganglion block improve the dysphagia and activities of daily living in patients with Parkinson's disease. Participants will be divided into the the control group and observation group evenly. All the patients were provided with routine therapy, while the patients in the observation group were given stellate ganglion block. The swallowing function, and activities of daily living of the two groups of patients before and after treatment were evaluated.

NCT ID: NCT06317792 Not yet recruiting - Clinical trials for Parkinsonism in Diseases Classified Elsewhere

The Efficacy of Online Exergaming-Integrated Physiotherapy for Parkinson's Disease

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

To validate the efficiency of online exergaming-based physiotherapy. We will enroll patients with Parkinson's disease in postural instability and gait disturbance motor phenotype in the study and divide them into two groups in a randomized controlled study.

NCT ID: NCT06303947 Not yet recruiting - Parkinson Disease Clinical Trials

Effect of Oral Enteral Nutrition Feeding in Parkinson Disease

Start date: March 2024
Phase: N/A
Study type: Interventional

The goal of this or clinical trial is to explore Intermittent Oro-esophageal Tube Feeding vs. Nasogastric Tube Feeding on nutritional status, dysphagia, and activities of daily living in patients with Parkinson's disease. The main question it aims to answer are: • Can stellate ganglion block improve the nutritional status, dysphagia, and activities of daily living in patients with Parkinson's disease, better than Nasogastric Tube Feeding. Participants will be divided into the control group and observation group evenly. All the patients were provided with routine therapy and given nutritional support by Intermittent Oro-esophageal Tube Feeding and Nasogastric Tube Feeding respectively. The nutritional status, swallowing function, and activities of daily living of the two groups of patients before and after treatment were evaluated.

NCT ID: NCT06303908 Not yet recruiting - Parkinson Disease Clinical Trials

How Traditional Chinese Medicine Exercise Improves Parkinson Disease

Start date: November 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to explore the impact of Simple Gymnastics Training on Limb motor function and mental health in Parkinson's Patients in the Community (≥60 year old) with swallowing disorders. It primarily aims to address two key aspects: 1) the prevalence of Parkinson's Diseases among community-dwelling elderly individuals, and 2) the effects of Simple Gymnastics Training on Limb motor function and mental health in community-dwelling Parkinson's Patients. All patients are required to undergo a continuous three-week (21 days) Simple Gymnastics Training, with weekends off and training conducted only on weekdays. The training will be conducted two sessions per day, lasting 30 minutes each.

NCT ID: NCT06302309 Not yet recruiting - Freezing of Gait Clinical Trials

Tackling Anxiety-related Freezing of Gait in People With Parkinson's Disease

TACKLING-FOG
Start date: March 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether personalized strategies that target anxiety and stress surrounding freezing of gait can alleviate freezing of gait in people with Parkinson's Disease.

NCT ID: NCT06301724 Not yet recruiting - Parkinson Disease Clinical Trials

Effectiveness of Stellate Ganglion Block in Individuals With Parkinson's Disease

Start date: March 2024
Phase: N/A
Study type: Interventional

The goal of this or clinical trial is to explore efficacy of stellate ganglion block on dysphagia and activities of daily living in patients with Parkinson's disease. The main question it aims to answer are: • Can stellate ganglion block improve the dysphagia and activities of daily living in patients with Parkinson's disease. Participants will be divided into the the control group and observation group evenly. All the patients were provided with routine therapy, while the patients in the observation group were given stellate ganglion block. The swallowing function, and activities of daily living of the two groups of patients before and after treatment were evaluated.

NCT ID: NCT06296810 Not yet recruiting - Parkinson Disease Clinical Trials

Adaptive DBS to Offset STN Dysregulation During Exercise in PD

Start date: March 2024
Phase:
Study type: Observational

The investigators conduct a prospective study to evaluate the effects of exercise on Parkinson's Disease brain biomarkers detected with the PerceptTM PC neurostimulator.