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Overweight clinical trials

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NCT ID: NCT01532375 Completed - Overweight Clinical Trials

Kochujang, a Fermented Soybean-based Red Pepper Paste, Decreases Visceral Fat and Improves Blood Lipid Profiles in Overweight Adults

Start date: October 2009
Phase: Phase 2
Study type: Interventional

With the epidemic of obesity and diabetes growing around the world, Kochujang (KCJ) may be potentially effective in preventing and treating obesity and cardiovascular risks if proven in humans. However, human trial still have not been reported with KCJ supplementation. In the present study, we investigated the hypothesis that KCJ supplementation can be decrease the body fat and improve blood lipid profiles in overweight adults.

NCT ID: NCT01530646 Completed - Obesity Clinical Trials

Impact of Whey and Soy Protein Ingestion in Conjunction With Energy Restriction in Overweight/Obese Individuals

Start date: February 2012
Phase: N/A
Study type: Interventional

It is known that dieting (restricted energy intake) without resistance training leads to a reduced metabolic rate, and the loss of both fat and muscle mass. When exercise is not included in a period of restricted energy intake, the degree to which muscle mass is lost is highly dependent upon protein consumption. Whey protein is a high quality protein isolated from milk and is known to stimulate new protein synthesis for all proteins in your body. Previous research has established that the consumption of whey protein has been correlated with retaining muscle mass while stimulating fat loss. However, the mechanisms behind these findings is still unknown. The purpose of this study is to establish a mechanistic underpinning to the efficacy of whey protein versus soy protein and a carbohydrate control (maltodextrin), in promoting fat mass loss and lean mass retention during a period of short-term controlled dietary energy deficit (-750 kcalories/day).

NCT ID: NCT01519583 Completed - Blood Pressure Clinical Trials

WalkMore Walking Interventions for Overweight/Obese Postmenopausal Women

Start date: May 2012
Phase: N/A
Study type: Interventional

The WalkMore study will help find out how walking interventions can help overweight/obese postmenopausal women with increased risk of cardiovascular disease lower their blood pressure.

NCT ID: NCT01514279 Completed - Overweight Clinical Trials

Ideas Moving Parents and Adolescents to Change Together (IMPACT)

IMPACT
Start date: February 1, 2011
Phase: N/A
Study type: Interventional

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institute of Health (NIH) has sponsored a consortium of four sites across the United States, entitled Childhood Obesity Prevention and Treatment Research (COPTR). Each site has its own protocol. Case Western Reserve/Cleveland's project is entitled "Targeting Obesity and Blood Pressure in Urban Youth". The site name is IMPACT (Ideas Moving Parents and Adolescents to Change Together). The project assesses the effects of three interventions on Body Mass Index(BMI) in overweight and obese urban 5th-8th grade youth: a cognitive-behavioral intervention (HealthyChange), a systems improvement intervention (SystemsChange), and an education-only intervention (Tools4Change). In addition the study assesses the potential additional impact of a school-community based intervention on outcomes. The project has two phases: a formative phase (including focus groups and a pilot) and the main trial. The main trial will take place over approximately four years.

NCT ID: NCT01509469 Completed - Obesity Clinical Trials

The Effect of Different Macronutrients on Ileal Brake Activation

Start date: March 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether ileal infusion of casein and sucrose can activate the ileal brake.

NCT ID: NCT01509365 Completed - Overweight Clinical Trials

Effect of Platelet Inhibition According to Clopidogrel Dose in Patients With Body Mass Index ≥ 27

PLATO-dose
Start date: December 2011
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine whether administration of 150 mg clopidogrel is effective in reducing the one-year incidence of thromboischemic events in patients with high on-clopidogrel platelet reactivity compared to 75 mg clopidogrel in the patient population overweight or obese with a body mass index (BMI) ≥ 27 kg.m-2.

NCT ID: NCT01509066 Completed - Obesity Clinical Trials

Healthy Eating for Reproductive Health (HERHealth)

HERHealth
Start date: January 2012
Phase: N/A
Study type: Interventional

This study will be a 6-month intervention that is examining how different dietary approached may be useful for women with Polycystic Ovarian Syndrome (PCOS) who are attempting pregnancy, particularly by measuring changes in weight. Participants will be randomly assigned to following one of two dietary approaches for weight loss: 1) a low-calorie approach to weight loss (reducing caloric intake by approximately 500 calories per day) or 2) a low-fat, low-glycemic index vegan diet. A vegan diet is one that does not contain any animal products (no meat, fish, poultry, eggs, or dairy) but emphasizes plant-based foods, such as fruits, vegetables, whole grains, and legumes/beans. In addition, this diet will be low-glycemic index, which means you will be asked to favor foods that don't cause a quick rise in blood sugar (for example, favoring oatmeal over cornflakes for breakfast). Participants will receive counseling and supporting materials on the dietary approach you are assigned to follow. Both diets are safe and have shown to be effective ways to assist with achieving a healthy weight. The investigators hypothesize that both groups will see improvements in weight and fertility with possible greater improvements seen among participants in the vegan group.

NCT ID: NCT01505387 Completed - Overweight Clinical Trials

Litramine in Weight Maintenance

Start date: January 2012
Phase: Phase 4
Study type: Interventional

The effect of Litramine on weight loss has previously been studied during a 12-week intervention period with promising results. The present study looks into the effect of weight maintenance using Litramine following initial weight loss, for a longer period of 24 weeks.

NCT ID: NCT01503047 Completed - Obesity Clinical Trials

Conjugated Linoleic Acid (1:1 Isomer Mixture) Intake in Overweight People

CLA
Start date: March 2008
Phase: Phase 4
Study type: Interventional

The aim of the study was to examine the effects and safety of 3 g of a 1:1 mix of c9-t11 and t10-c12 (Tonalin®) on weight control and body composition in healthy overweight individuals who maintained their normal dietary and exercise patterns.

NCT ID: NCT01502007 Completed - Obesity Clinical Trials

Activity Monitoring and Counseling in a Geriatric Population

Start date: April 2011
Phase: N/A
Study type: Interventional

The goal of the study is to determine if a Fitbit, a kind of accelerometer, provides feedback to subjects combined with an activity counseling program will result in an increase in physical activity of at least 20%.