Multivessel Coronary Artery Disease Clinical Trial
Official title:
Influence of Total Atherosclerotic Burden Assessed by 3-vessel Fractional Flow Reserve (FFR) on the Clinical Outcomes of the Patients With Multi-vessel Disease
This study will evaluate the influence of total atherosclerotic burden assessed by 3-vessel fractional flow reserve (FFR) on the clinical outcomes of the patients with multi-vessel disease. For this purpose, the clinical data of the patients with 3-vessel intermediate coronary artery disease, whose FFR was measured at all 3-vessels due to their own clinical needs, will be analyzed.
Primary Analysis The Primary Analysis will be performed after 2-year follow-up data will be
completed.
Pre-specified Subgroup Analysis
The pre-specified subgroup analysis will perform after 1-year follow-up data will be
completed according to the following subjects:
- Concordant and discordant results between FFR and angiographic stenosis severity
(patients and lesions with pre-PCI FFR will be analyzed.).
- Association between total atherosclerotic burden and total ischemic burden,
coronary CT angiography substudy (after 2-year follow-up will be completed).
- Validation of total ischemic burden (sum of 3 vessel FFR) with Duke score,
measured by treadmill test.
- Comparison of clinical outcomes of deferred lesions according to pre-PCI
FFR levels (Pre-PCI FFR <0.75, 0.75-0.80, and >0.80).
- Comparison of clinical outcomes of deferred lesions according to iFR
and FFR values ⑥ Prognosis of functional complete revascularization
versus incomplete revascularization
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT05669222 -
The FAVOR V AMI Trial
|
N/A | |
| Not yet recruiting |
NCT06025071 -
Residual Inflammatory Risk-Guided colcHicine in Elderly Trial
|
Phase 4 | |
| Recruiting |
NCT05786131 -
Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI
|
N/A | |
| Recruiting |
NCT06168305 -
Safety and Effectiveness of GENOSS DES in Patients With Multivessel Coronary Artery Disease
|
||
| Not yet recruiting |
NCT05835167 -
Complete Revascularization Via Inferior Part-sternotomy
|
N/A | |
| Completed |
NCT01881555 -
Functional Testing Underlying Coronary Revascularisation
|
N/A | |
| Not yet recruiting |
NCT06378775 -
Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery
|
N/A | |
| Completed |
NCT05125367 -
Ten-Year Outcomes of Randomized Comparison of Coronary Artery Bypass Surgery and Everolimus-Eluting Stent Implantation in the Treatment of Patients With Multivessel Coronary Artery Disease
|
||
| Completed |
NCT01947439 -
Comparison of the Biolimus A9-eluting Stent With the Zotarolimus -Eluting Stent in Multi-vessel PCI
|
N/A | |
| Recruiting |
NCT05333068 -
COMBINE-INTERVENE: COMBINEd Ischemia and Vulnerable Plaque Percutaneous INTERVENtion to Reduce Cardiovascular Events
|
N/A | |
| Withdrawn |
NCT03851276 -
A Multicentre, Pilot Study to Evaluate the Safety and the Feasibility of Planning and Execution of Surgical Revascularization in Patients With Complex Coronary Artery Disease, Based Solely on MSCT Imaging Utilizing GE Healthcare Revolution CT and HeartFlow FFRCT.
|
Phase 4 | |
| Completed |
NCT02813473 -
SYNTAX III REVOLUTION Trial: A Randomized Study Investigating the Use of CT Scan and Angiography of the Heart to Help the Doctors Decide Which Method is the Best to Improve Blood Supply to the Heart in Patients With Complex Coronary Artery Disease
|
||
| Recruiting |
NCT05698719 -
Validation of vFFR as Compared to FFR to Guide Revascularization of Non-culprit Lesions in STEMI Patients
|
||
| Completed |
NCT01399736 -
Comparison Between FFR Guided Revascularization Versus Conventional Strategy in Acute STEMI Patients With MVD.
|
N/A | |
| Not yet recruiting |
NCT01311323 -
Revascularization Strategies in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome (NSTE-ACS) and Severe Coronary Artery Disease
|
N/A | |
| Completed |
NCT00818792 -
Randomized Comparison of xiEnce and visioN Coronary Stents in the sAme muLtivessel Patient With Chronic kiDnEy diSease
|
Phase 2 | |
| Completed |
NCT01199419 -
Cost-effectiveness of PCI With Taxus vs CABG - 5 Years FUP
|
N/A | |
| Completed |
NCT04743154 -
In-hospital Versus After-discharge Complete Revascularization
|
N/A | |
| Terminated |
NCT02334826 -
Revascularization With BVS or CABG in Patients With Advanced CAD
|
Phase 4 | |
| Recruiting |
NCT04811586 -
Efficacy and Safety of One-Stage Hybrid Coronary Revascularization
|
N/A |