Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD

Comorbidities and Coexisting Conditions Clinical Trial

Official title:

Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05504993
• Other study ID #: 05-305-18
• Status: Completed
• Start date: January 1, 2018
• Est. completion date: January 1, 2022

Study information

• Verified date: August 2022
• Source: Ankara University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

INTRODUCTION: Relationship between comorbidities and COPD is two-sided. While the number of comorbidities increasing, the frequency of acute exacerbations of COPD (AECOPD) is increasing, too. Comorbidity indexes can be used for recognition of comorbidities while managing COPD patients. In the present study, it is aimed to compare comorbidity indexes such as Charlson Comorbidity Index, COMCOLD and COTE in the matter of exacerbation frequency. METHOD: Subjects hospitalized for AECOPD, admitted to the study. Exacerbation severity, frequency, further exacerbations for a 1-year period in the follow-up period and CCI, COMCOLD and COTE scores were recorded. High and low comorbidity groups were compared for AECOPD frequency, severity, and further exacerbations.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 92
• Est. completion date: January 1, 2022
• Est. primary completion date: July 1, 2018
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• COPD patients
• Admitted to the ward for AECOPD

Exclusion Criteria:

• Not giving informed consent
• Unable to perform PFT
• Lost to follow-up

Related Conditions & MeSH terms

• Acute Exacerbation of COPD
• Chronic Obstructive Lung Disease
• Comorbidities and Coexisting Conditions
• Lung Diseases
• Lung Diseases, Obstructive
• Pulmonary Disease, Chronic Obstructive

Intervention

Other:
• Frequency of AECOPD
No intervention has been applied. 92 COPD patients divided into 2 groups according to their comorbidity level. Than these groups were compared for their AECOPD frequency

Locations

Country	Name	City	State
Turkey	Ankara University Faculty of Medicine	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Ankara University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Frequency of AECOPD	Frequency of AECOPD in the last one year	1 year
Secondary	Having at least one severe AECOPD	having at least one severe AECOPD in the last year	1 year
Secondary	Frequency of AECOPD for the next one year	the number of AECOPD for 1 year period from the preceding admission, regardless of severity	1 year