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Clinical Trial Summary

Inspiratory muscle training for 8 weeks in patients with chronic thromboembolic pulmonary hypertension.


Clinical Trial Description

32 patients with CTEPH (confirmed by right cardiac catheterization and imaging) will perform: 1) pulmonary function tests; 2) measurement of maximal inspiratory pressure (MIP) and endurance; 3) evaluation of peripheral muscle strength by isokinetic dynamometry; 4) six-minute walk test and 5) incremental and constant load cardiopulmonary exercise test (~ 75% of maximal work-rate) with non-invasive evaluation of central hemodynamics and peripheral muscle oxygenation. Inspiratory muscle training will consist of twice daily sessions of 30 breaths (~ 50% PiMAX, 4-5 minutes per session) for 8 weeks. The SHAM group will perform sessions of 30 breaths with no inspiratory load. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03102294
Study type Interventional
Source Federal University of São Paulo
Contact Roberta P Ramos, MD, PhD
Phone 551150824420
Email robertapulcheri@gmail.com
Status Not yet recruiting
Phase N/A
Start date September 1, 2017
Completion date April 30, 2019

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