Patients With Asthma-COPD Overlap Syndrome (ACOS) Clinical Trial
Official title:
A Cross-sectional Study to Determine the Proportion and Clinical Characteristics of COPD Patients With Asthma Symptoms in Asia (ACOS) and Describe Current Practices in Diagnosis and Management
The purpose of this study to determine the proportion and clinical characteristics of COPD patients with asthma symptoms (ACOS) and describe current practices in diagnosis and management in Viet Nam and Taiwan.
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of chronic morbidity and
mortality. Around 15% to 20% of COPD patients would present with features of asthma and are
considered to have the overlap syndrome of COPD and asthma, commonly called asthma-COPD
overlap syndrome (ACOS). In Asia, specifically Taiwan, the overall prevalence of ACOS in
patients with COPD is approximately 17.4%. COPD patients with asthma symptoms represent a
relevant clinical population because they have worse health-related quality of life.
Given the increased morbidity among COPD patients with asthma overlap, it is critical that
these patients are properly characterized to aid the appropriate diagnosis and treatment. The
Global Initiative for Asthma (GINA) and Global Initiative for Chronic Obstructive Lung
Disease (GOLD) guidelines have given joint recommendations on the identification, diagnosis
and treatment of these patients. These recommendations have been adapted for use in the Asia
Area countries. The primary objective of this study is to determine the proportion and
clinical characteristics of patients with ACOS as defined by the joint GINA and GOLD
recommendation amongst diagnosed COPD patients seen at the out-patient clinics.
This study is planned to determine the proportion of patients with ACOS as defined by the
joint GINA and GOLD recommendation amongst diagnosed COPD patients seen at the out-patient
clinics
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