Chronic Thromboembolic Pulmonary Hypertension Clinical Trial
Official title:
Identification Of The Predictive Angiographic And Computed Tomographic (CT) Criteria Of The Success Of The Thromboendarterectomy In Chronic Pulmonary Hypertension
In order to improve effectiveness of the surgical operation thanks to a reduction in the rate of failure, this study will allow us to identify predictive angiographic and CT finding of surgical failure, starting from standardized reading grids, in order to have a better selection of the operable patients.
Chronic thromboembolic pulmonary hypertension(CTEPH) is caused by obstruction of the large
pulmonary arteries by acute and recurrent pulmonary emboli, and organization of these blood
clots. ANTOINE BECLERE respiratory unit, in partnership with the MARIE LANNELONGUE hospital
thoracic and vascular surgery departments was designated recently as reference national
centre for pulmonary hypertension and represents the only French structure for evaluation of
CTEPH with 150 patients addressed each year.If the disease is proximately located, CTEPH can
be cured surgically through a complex surgical procedure performed under Hypothermia and
total circulatory arrest. In spite of multidisciplinary meeting deciding the operability of
each case the rate of failure is approximately of 15% (9% of operative mortality rate and 6%
of technical failure).
The aim of this study is to identify predictive angiographic and CT findings of success, by
allowing a better selection of operable patients.
It would be possible to improve the effectiveness of the surgical treatment and reduce the
rate failure from 15% to 7 % or even 5 %.
;
Intervention Model: Single Group Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Diagnostic
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